(data stored in SCRATCH zone)

SWISSPROT: Q82QE7_STRAW

ID   Q82QE7_STRAW            Unreviewed;       672 AA.
AC   Q82QE7;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   08-MAY-2019, entry version 88.
DE   SubName: Full=Putative acetoacetyl-CoA synthetase {ECO:0000313|EMBL:BAC68272.1};
GN   Name=acsA3 {ECO:0000313|EMBL:BAC68272.1};
GN   ORFNames=SAVERM_562 {ECO:0000313|EMBL:BAC68272.1};
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 /
OS   NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC68272.1, ECO:0000313|Proteomes:UP000000428};
RN   [1] {ECO:0000313|EMBL:BAC68272.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C.,
RA   Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T.,
RA   Kikuchi H., Shiba T., Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces
RT   avermitilis: deducing the ability of producing secondary
RT   metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2] {ECO:0000313|EMBL:BAC68272.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
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DR   EMBL; BA000030; BAC68272.1; -; Genomic_DNA.
DR   RefSeq; WP_010982000.1; NZ_JZJK01000088.1.
DR   STRING; 227882.SAV_562; -.
DR   EnsemblBacteria; BAC68272; BAC68272; SAVERM_562.
DR   KEGG; sma:SAVERM_562; -.
DR   eggNOG; ENOG4108IQF; Bacteria.
DR   eggNOG; COG0365; LUCA.
DR   HOGENOM; HOG000229992; -.
DR   KO; K01907; -.
DR   OMA; RHVPKYV; -.
DR   OrthoDB; 141801at2; -.
DR   BioCyc; SAVE227882:G1G23-633-MONOMER; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.12780; -; 1.
DR   InterPro; IPR005914; Acac_CoA_synth.
DR   InterPro; IPR032387; ACAS_N.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   InterPro; IPR042099; AMP-dep_Synthh-like_sf.
DR   Pfam; PF16177; ACAS_N; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   TIGRFAMs; TIGR01217; ac_ac_CoA_syn; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
DR   PRODOM; Q82QE7.
DR   SWISS-2DPAGE; Q82QE7.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000428};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000428}.
FT   DOMAIN       48    104       ACAS_N. {ECO:0000259|Pfam:PF16177}.
FT   DOMAIN      109    536       AMP-binding. {ECO:0000259|Pfam:PF00501}.
FT   DOMAIN      549    624       AMP-binding_C. {ECO:0000259|Pfam:
FT                                PF13193}.
SQ   SEQUENCE   672 AA;  72224 MW;  D741B526125F567A CRC64;
     MTTPHPAPYP EPFFTPDPKS AAHSRIADFA RWAARHQGAE GIQDPTDYRA LYQWSVTDLE
     GFWAAVWEYF DIDATTEYEG VLAEETMPGA RWFPGATLNY VHHALRNLQP DAPAITALDE
     TGAGYEITGR ELRARVASVA ASLRDLGVAQ GDRVVGYLPN TPHAVIAFLA TASLGAVWSV
     CGQDYVPKAA ADRFAQLEPT VLITADGYLF NGTTHDRRAA SLELAVALPT LKATVLVDHV
     GLAWPEGGDL GLTVPWEDAA TRAEYLTIAP VPFDHPLWVV FSSGTTGLPK GIVHGHGGVL
     LEHLKMLGLH TDLGIGDRLL WYTTTHWMMW NLVVSTLLTG ATTCTYDGSP APQARPDVLW
     ELAARHKVTV FGTSPQYLLA MSKLGIAPSV YDLSAIRVVG CTGSALPASA YPWVRDHVGA
     GVQLASTSGG TDIVSGFAGS AATTPVWAGE LSAPGLGVAL AAYDEEGLPV TDRVGELVVT
     RPMPSMPLYF WNDPDGSRYR DAYFGAYPGV WRHGDWITLT SHGSVIVHGR SDATLNRNGV
     RLGSADIHDV VERLPEITEA LVIGAEEPDG GYWMPLFVVL ADGVGLDDSL RAKIRDAIRA
     GASPRHVPDE ILAVPALPHT KTGKKLEVPV KRLLQGAPAE QVLNPSAVDN PDLIAYFARL
     GAERNKRSAH HT
//

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