(data stored in SCRATCH zone)

SWISSPROT: Q82R06_STRAW

ID   Q82R06_STRAW            Unreviewed;       303 AA.
AC   Q82R06;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   08-MAY-2019, entry version 117.
DE   SubName: Full=Putative lactate dehydrogenase {ECO:0000313|EMBL:BAC68048.1};
GN   Name=ldhA {ECO:0000313|EMBL:BAC68048.1};
GN   ORFNames=SAVERM_339 {ECO:0000313|EMBL:BAC68048.1};
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 /
OS   NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC68048.1, ECO:0000313|Proteomes:UP000000428};
RN   [1] {ECO:0000313|EMBL:BAC68048.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C.,
RA   Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T.,
RA   Kikuchi H., Shiba T., Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces
RT   avermitilis: deducing the ability of producing secondary
RT   metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2] {ECO:0000313|EMBL:BAC68048.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
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DR   EMBL; BA000030; BAC68048.1; -; Genomic_DNA.
DR   STRING; 227882.SAV_339; -.
DR   EnsemblBacteria; BAC68048; BAC68048; SAVERM_339.
DR   KEGG; sma:SAVERM_339; -.
DR   eggNOG; ENOG4105C80; Bacteria.
DR   eggNOG; COG0039; LUCA.
DR   KO; K00016; -.
DR   OMA; EEPINGH; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR   Gene3D; 3.90.110.10; -; 1.
DR   InterPro; IPR001557; L-lactate/malate_DH.
DR   InterPro; IPR001236; Lactate/malate_DH_N.
DR   InterPro; IPR015955; Lactate_DH/Glyco_Ohase_4_C.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00056; Ldh_1_N; 1.
DR   PIRSF; PIRSF000102; Lac_mal_DH; 1.
DR   PRINTS; PR00086; LLDHDRGNASE.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   SUPFAM; SSF56327; SSF56327; 1.
PE   4: Predicted;
DR   PRODOM; Q82R06.
DR   SWISS-2DPAGE; Q82R06.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000428};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000428}.
FT   DOMAIN        4    137       Ldh_1_N. {ECO:0000259|Pfam:PF00056}.
FT   ACT_SITE    173    173       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000102-1}.
FT   BINDING      90     90       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR000102-2}.
FT   BINDING     120    120       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR000102-2}.
FT   BINDING     149    149       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR000102-2}.
SQ   SEQUENCE   303 AA;  31147 MW;  FF7800D3885B8198 CRC64;
     MGSVGVVGAG AVGQTVAATL VASGICPRLL VVSRTVEQAR ALAADLDDMR QTTGSPVQPE
     ARRVADLIGC HAVVVAVRAA FTNTRAADVR MGGALTNAPV IRALATTLRG YQGTVLVVTN
     PVDLMTRLFA ETSGCPRVYG IGSNLDSARY RLTLAHLLDV PATTVHGHVI GEHGDGAVVC
     ASSTTVNGTP AAVPLAEVRA ELRTRPGQIS AGVGRTRSGP AGAVLSTLRK ALGLVDGTEE
     LTAEHRGDWL GIPLRFTAGQ PVACLPALNA DEDAQLAATA TKLRDAYQAL RPSGPTPNSQ
     ETT
//

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