(data stored in ACNUC22857 zone)

SWISSPROT: Q8CC13_MOUSE

ID   Q8CC13_MOUSE            Unreviewed;       953 AA.
AC   Q8CC13;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   30-AUG-2017, entry version 109.
DE   RecName: Full=AP complex subunit beta {ECO:0000256|PIRNR:PIRNR002291};
GN   Name=Ap1b1 {ECO:0000313|MGI:MGI:1096368};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1] {ECO:0000313|EMBL:BAC28603.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=C57BL/6J {ECO:0000313|EMBL:BAC28603.1};
RC   TISSUE=Diencephalon {ECO:0000313|EMBL:BAC28603.1};
RX   PubMed=10349636; DOI=10.1016/S0076-6879(99)03004-9;
RA   Carninci P., Hayashizaki Y.;
RT   "High-efficiency full-length cDNA cloning.";
RL   Methods Enzymol. 303:19-44(1999).
RN   [2] {ECO:0000313|EMBL:BAC28603.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=C57BL/6J {ECO:0000313|EMBL:BAC28603.1};
RC   TISSUE=Diencephalon {ECO:0000313|EMBL:BAC28603.1};
RX   PubMed=11042159; DOI=10.1101/gr.145100;
RA   Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M.,
RA   Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.;
RT   "Normalization and subtraction of cap-trapper-selected cDNAs to
RT   prepare full-length cDNA libraries for rapid discovery of new genes.";
RL   Genome Res. 10:1617-1630(2000).
RN   [3] {ECO:0000313|EMBL:BAC28603.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=C57BL/6J {ECO:0000313|EMBL:BAC28603.1};
RC   TISSUE=Diencephalon {ECO:0000313|EMBL:BAC28603.1};
RX   PubMed=11076861; DOI=10.1101/gr.152600;
RA   Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P.,
RA   Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M.,
RA   Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A.,
RA   Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K.,
RA   Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M.,
RA   Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J.,
RA   Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.;
RT   "RIKEN integrated sequence analysis (RISA) system--384-format
RT   sequencing pipeline with 384 multicapillary sequencer.";
RL   Genome Res. 10:1757-1771(2000).
RN   [4] {ECO:0000313|EMBL:BAC28603.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=C57BL/6J {ECO:0000313|EMBL:BAC28603.1};
RC   TISSUE=Diencephalon {ECO:0000313|EMBL:BAC28603.1};
RX   PubMed=11217851; DOI=10.1038/35055500;
RG   The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium;
RT   "Functional annotation of a full-length mouse cDNA collection.";
RL   Nature 409:685-690(2001).
RN   [5] {ECO:0000313|EMBL:BAC28603.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=C57BL/6J {ECO:0000313|EMBL:BAC28603.1};
RC   TISSUE=Diencephalon {ECO:0000313|EMBL:BAC28603.1};
RA   Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P.,
RA   Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W.,
RA   Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T.,
RA   Hori F., Imotani K., Ishii Y., Itoh M., Kagawa I., Kasukawa T.,
RA   Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S.,
RA   Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M.,
RA   Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y.,
RA   Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H.,
RA   Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M.,
RA   Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T.,
RA   Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.;
RL   Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
RN   [6] {ECO:0000313|EMBL:BAC28603.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=C57BL/6J {ECO:0000313|EMBL:BAC28603.1};
RC   TISSUE=Diencephalon {ECO:0000313|EMBL:BAC28603.1};
RX   PubMed=12466851; DOI=10.1038/nature01266;
RG   The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team;
RT   "Analysis of the mouse transcriptome based on functional annotation of
RT   60,770 full-length cDNAs.";
RL   Nature 420:563-573(2002).
RN   [7] {ECO:0000313|EMBL:BAC28603.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=C57BL/6J {ECO:0000313|EMBL:BAC28603.1};
RC   TISSUE=Diencephalon {ECO:0000313|EMBL:BAC28603.1};
RG   The FANTOM Consortium;
RG   Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group);
RT   "The Transcriptional Landscape of the Mammalian Genome.";
RL   Science 309:1559-1563(2005).
RN   [8] {ECO:0000313|EMBL:BAC28603.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=C57BL/6J {ECO:0000313|EMBL:BAC28603.1};
RC   TISSUE=Diencephalon {ECO:0000313|EMBL:BAC28603.1};
RX   PubMed=16141073; DOI=10.1126/science.1112009;
RG   RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium;
RT   "Antisense Transcription in the Mammalian Transcriptome.";
RL   Science 309:1564-1566(2005).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00556307}.
CC   -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC       {ECO:0000256|PIRNR:PIRNR002291}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AK034140; BAC28603.1; -; mRNA.
DR   RefSeq; NP_001229972.1; NM_001243043.1.
DR   RefSeq; NP_001229973.1; NM_001243044.1.
DR   RefSeq; NP_031480.2; NM_007454.3.
DR   RefSeq; XP_006514524.1; XM_006514461.1.
DR   RefSeq; XP_006514525.1; XM_006514462.3.
DR   UniGene; Mm.274816; -.
DR   ProteinModelPortal; Q8CC13; -.
DR   IntAct; Q8CC13; 2.
DR   MINT; MINT-4115053; -.
DR   SwissPalm; Q8CC13; -.
DR   MaxQB; Q8CC13; -.
DR   PaxDb; Q8CC13; -.
DR   PeptideAtlas; Q8CC13; -.
DR   PRIDE; Q8CC13; -.
DR   GeneID; 11764; -.
DR   KEGG; mmu:11764; -.
DR   UCSC; uc007hvn.2; mouse.
DR   CTD; 162; -.
DR   MGI; MGI:1096368; Ap1b1.
DR   eggNOG; KOG1061; Eukaryota.
DR   eggNOG; COG5096; LUCA.
DR   HOGENOM; HOG000163270; -.
DR   HOVERGEN; HBG050515; -.
DR   KO; K12392; -.
DR   PhylomeDB; Q8CC13; -.
DR   ChiTaRS; Ap1b1; mouse.
DR   Genevisible; Q8CC13; MM.
DR   GO; GO:0030131; C:clathrin adaptor complex; IEA:InterPro.
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   Gene3D; 1.25.10.10; -; 1.
DR   Gene3D; 2.60.40.1150; -; 1.
DR   InterPro; IPR026739; AP_beta.
DR   InterPro; IPR016342; AP_complex_bsu_1_2_4.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000225; Armadillo.
DR   InterPro; IPR015151; B-adaptin_app_sub_C.
DR   InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR   InterPro; IPR008152; Clathrin_a/b/g-adaptin_app_Ig.
DR   InterPro; IPR013037; Clathrin_b-adaptin_app_Ig-like.
DR   InterPro; IPR009028; Coatomer/calthrin_app_sub_C.
DR   InterPro; IPR013041; Coatomer/clathrin_app_Ig-like.
DR   PANTHER; PTHR11134; PTHR11134; 1.
DR   Pfam; PF01602; Adaptin_N; 1.
DR   Pfam; PF02883; Alpha_adaptinC2; 1.
DR   Pfam; PF09066; B2-adapt-app_C; 1.
DR   PIRSF; PIRSF002291; AP_complex_beta; 1.
DR   SMART; SM00809; Alpha_adaptinC2; 1.
DR   SMART; SM00185; ARM; 2.
DR   SMART; SM01020; B2-adapt-app_C; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   SUPFAM; SSF49348; SSF49348; 1.
DR   SUPFAM; SSF55711; SSF55711; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; Q8CC13.
DR   SWISS-2DPAGE; Q8CC13.
KW   Membrane {ECO:0000256|PIRNR:PIRNR002291,
KW   ECO:0000256|SAAS:SAAS00101884};
KW   Protein transport {ECO:0000256|PIRNR:PIRNR002291,
KW   ECO:0000256|SAAS:SAAS00468902};
KW   Transport {ECO:0000256|PIRNR:PIRNR002291,
KW   ECO:0000256|SAAS:SAAS00299740}.
FT   DOMAIN      720    830       Alpha_adaptinC2. {ECO:0000259|SMART:
FT                                SM00809}.
FT   DOMAIN      839    952       B2-adapt-app_C. {ECO:0000259|SMART:
FT                                SM01020}.
SQ   SEQUENCE   953 AA;  104998 MW;  DD97D86F52FE2910 CRC64;
     MTDSKYFTTT KKGEIFELKA ELNSDKKEKK KEAVKKVIAS MTVGKDVSAL FPDVVNCMQT
     DNLELKKLVY LYLMNYAKSQ PDMAIMAVNT FVKDCEDPNP LIRALAVRTM GCIRVDKITE
     YLCEPLRKCL KDEDPYVRKT AAVCVAKLHD INAQLVEDQG FLDTLKDLIS DSNPMVVANA
     VAALSEIAES HPSSNLLDLN PQSINKLLTA LNECTEWGQI FILDCLANYM PKDDREAQSI
     CERVTPRLSH ANSAVVLSAV KVLMKFMEML SKDLDYYATL LKKLAPPLVT LLSAEPELQY
     VALRNINLIV QKRPEILKHE MKVFFVKYND PIYVKLEKLD IMIRLASQAN IAQVLAELKE
     YATEVDVDFV RKAVRAIGRC AIKVEQSAER CVSTLLDLIQ TKVNYVVQEA IVVIKDIFRK
     YPNKYESVIA TLCENLDSLD EPEARAAMIW IVGEYAERID NADELLESFL EGFHDESTQV
     QLQLLTAIVK LFLKKPTETQ ELVQQVLSLA TQDSDNPDLR DRGYIYWRLL STDPVAAKEV
     VLAEKPLISE ETDLIEPTLL DELICYIGTL ASVYHKPPNA FVEGGRGVVH KSLPPRTASS
     ESTESPETAP AGAPAGDQPD VIPAQGDLLG DLLNLDLGPP VSGPPLAASS VQMGAVDLLG
     GGLDSLMGDE SEGIGDSNFG APSASVAAAP APARLGAPIS SGLSDLFDLT SGVGTLSGSY
     VAPKAVWLPA MKAKGLEISG TFTRQAGSIS MDLQLTNKAL QVMTDFAIQF NRNSFGLAPA
     APLQVHVPLS PNQTVEISLP LNTVGSVLKM EPLNNLQVAV KNNIDVFYFS TLYPLHVLFV
     EDGKMDRQMF LATWKDIANE NEAQFQIRDC PLNTEAASNK LQSSNIFTVA KRNVEGQDML
     YQSLKLTNGI WVLAELRIQP GNPSFTDLEL SLKCRAPEVS QHVYQAYETI LKN
//

If you have problems or comments...

PBIL Back to PBIL home page