(data stored in SCRATCH zone)

SWISSPROT: Q8IAT2_PLAF7

ID   Q8IAT2_PLAF7            Unreviewed;       520 AA.
AC   Q8IAT2;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   08-MAY-2019, entry version 118.
DE   RecName: Full=RuvB-like helicase {ECO:0000256|RuleBase:RU363048};
DE            EC=3.6.4.12 {ECO:0000256|RuleBase:RU363048};
GN   ORFNames=PF3D7_0809700 {ECO:0000313|EMBL:CAD51278.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAD51278.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.,
RA   Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S.,
RA   Chan M.S., Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S.,
RA   Pertea M., Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B.,
RA   Martin D.M., Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A.,
RA   McFadden G.I., Cummings L.M., Subramanian G.M., Mungall C.,
RA   Venter J.C., Carucci D.J., Hoffman S.L., Newbold C., Davis R.W.,
RA   Fraser C.M., Barrell B.;
RT   "Genome sequence of the human malaria parasite Plasmodium
RT   falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C.,
RA   Chillingworth T., Christodoulou Z., Clark L., Clark R., Corton C.,
RA   Cronin A., Davies R.M., Davis P., Dear P., Dearden F., Doggett J.,
RA   Feltwell T., Goble A., Goodhead I., Gwilliam R., Hamlin N., Hance Z.,
RA   Harper D., Hauser H., Hornsby T., Holroyd S., Horrocks P.,
RA   Humphray S., Jagels K., James K.D., Johnson D., Kerhornou A.,
RA   Knights A., Konfortov B., Kyes S., Larke N., Lawson D., Lennard N.,
RA   Line A., Maddison M., Mclean J., Mooney P., Moule S., Murphy L.,
RA   Oliver K., Ormond D., Price C., Quail M.A., Rabbinowitsch E.,
RA   Rajandream M.A., Rutter S., Rutherford K.M., Sanders M., Simmonds M.,
RA   Seeger K., Sharp S., Smith R., Squares R., Squares S., Stevens K.,
RA   Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|RuleBase:RU363048,
CC         ECO:0000256|SAAS:SAAS01117400};
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|SAAS:SAAS00005491}.
CC   -!- SIMILARITY: Belongs to the RuvB family.
CC       {ECO:0000256|RuleBase:RU363048, ECO:0000256|SAAS:SAAS00536598}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AL844507; CAD51278.1; -; Genomic_DNA.
DR   RefSeq; XP_001349429.1; XM_001349393.1.
DR   SMR; Q8IAT2; -.
DR   PRIDE; Q8IAT2; -.
DR   EnsemblProtists; CAD51278; CAD51278; PF3D7_0809700.
DR   GeneDB; PF3D7_0809700.1:pep; -.
DR   GeneID; 2655299; -.
DR   KEGG; pfa:PF3D7_0809700; -.
DR   EuPathDB; PlasmoDB:PF3D7_0809700; -.
DR   HOGENOM; HOG000190885; -.
DR   InParanoid; Q8IAT2; -.
DR   KO; K04499; -.
DR   OMA; LECFTYL; -.
DR   PhylomeDB; Q8IAT2; -.
DR   Proteomes; UP000001450; Chromosome 8.
DR   GO; GO:0031011; C:Ino80 complex; IBA:GO_Central.
DR   GO; GO:0035267; C:NuA4 histone acetyltransferase complex; IBA:GO_Central.
DR   GO; GO:0097255; C:R2TP complex; IBA:GO_Central.
DR   GO; GO:0000812; C:Swr1 complex; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043141; F:ATP-dependent 5'-3' DNA helicase activity; IDA:GeneDB.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; IBA:GO_Central.
DR   GO; GO:0016887; F:ATPase activity; IDA:GeneDB.
DR   GO; GO:0003678; F:DNA helicase activity; IDA:GeneDB.
DR   GO; GO:0000492; P:box C/D snoRNP assembly; IBA:GO_Central.
DR   GO; GO:0006338; P:chromatin remodeling; IBA:GO_Central.
DR   GO; GO:0016573; P:histone acetylation; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR027238; RuvB-like.
DR   InterPro; IPR041048; RuvB-like_C.
DR   InterPro; IPR037938; RUVBL1.
DR   InterPro; IPR010339; TIP49_P-loop.
DR   PANTHER; PTHR11093; PTHR11093; 1.
DR   PANTHER; PTHR11093:SF6; PTHR11093:SF6; 1.
DR   Pfam; PF06068; TIP49; 1.
DR   Pfam; PF17856; TIP49_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q8IAT2.
DR   SWISS-2DPAGE; Q8IAT2.
KW   ATP-binding {ECO:0000256|RuleBase:RU363048,
KW   ECO:0000256|SAAS:SAAS00005499}; Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001450};
KW   Helicase {ECO:0000256|RuleBase:RU363048,
KW   ECO:0000256|SAAS:SAAS00005493, ECO:0000313|EMBL:CAD51278.1};
KW   Hydrolase {ECO:0000256|RuleBase:RU363048,
KW   ECO:0000256|SAAS:SAAS00005492, ECO:0000313|EMBL:CAD51278.1};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU363048,
KW   ECO:0000256|SAAS:SAAS00005486};
KW   Nucleus {ECO:0000256|RuleBase:RU363048,
KW   ECO:0000256|SAAS:SAAS00005485};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450};
KW   Transcription {ECO:0000256|RuleBase:RU363048};
KW   Transcription regulation {ECO:0000256|RuleBase:RU363048}.
FT   DOMAIN      132    429       AAA. {ECO:0000259|SMART:SM00382}.
FT   COILED      323    343       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   520 AA;  59595 MW;  91E1A981171B71EB CRC64;
     MNIIESSREK ERISLHSHIS GLGLDADGYV TDFLFEENIK KRDMYSEPTN KIENNDIKNG
     TILDPDKVDN ICNSYKLENN GNYENNKICY NNISDDEDEV VKNFYKCKGM VGQKKAREAA
     GIFINLIKEK NICKCLLLAG PSGSGKTAIA IAISKEISDE SIPFCIFNAS QVYSCEVKKT
     EILTQYIRKS IGVKIKEIKE VFEGEVVQIE PFFDNTYDEQ KISYVHITLK TLKEQKKIKI
     HSSIYDNLLK EKIQEKDIIY IESHSGNVKR VGKCSLYQDM FDIETDTFVD LPKGNVHKKK
     NIIQNITLYD LDVSNVQPKD NILDFLQNNK SKKTEITDKL RNEINKIVYK YVDQGIAQII
     PGVLFIDEVH MLDIECFTYL NRTLESNLAP VVILATNRGI CNIKGTNIIS AHGIPVDLLD
     RIIIVKTMLY NKEEILQVLK LRCKFERIKI DSEALDYLSD IGIKCSLRYA IQLLTPAKIL
     SKKKGKKKID KNIIEIVSSI FFDTKRSTQL LLNDKNKYMY
//

If you have problems or comments...

PBIL Back to PBIL home page