(data stored in SCRATCH zone)

SWISSPROT: Q8IAX3_PLAF7

ID   Q8IAX3_PLAF7            Unreviewed;      1419 AA.
AC   Q8IAX3;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   11-DEC-2019, entry version 115.
DE   SubName: Full=ABC transporter F family member 1 {ECO:0000313|EMBL:CAD51237.1};
GN   ORFNames=PF3D7_0813700 {ECO:0000313|EMBL:CAD51237.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAD51237.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA   Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA   Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA   Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA   Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA   Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA   Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT   "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA   Christodoulou Z., Clark L., Clark R., Corton C., Cronin A., Davies R.M.,
RA   Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA   Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA   Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D.,
RA   Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N.,
RA   Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P.,
RA   Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA   Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M.,
RA   Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA   Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
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DR   EMBL; AL844507; CAD51237.1; -; Genomic_DNA.
DR   RefSeq; XP_001349388.1; XM_001349352.1.
DR   IntAct; Q8IAX3; 2.
DR   EnsemblProtists; CAD51237; CAD51237; PF3D7_0813700.
DR   GeneDB; PF3D7_0813700.1:pep; -.
DR   GeneID; 2655277; -.
DR   KEGG; pfa:PF3D7_0813700; -.
DR   EuPathDB; PlasmoDB:PF3D7_0813700; -.
DR   HOGENOM; HOG000280939; -.
DR   InParanoid; Q8IAX3; -.
DR   KO; K15073; -.
DR   OMA; SECVGLI; -.
DR   BioCyc; PLASMO:PF08_0078-MONOMER; -.
DR   Proteomes; UP000001450; Chromosome 8.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IBA:GO_Central.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 3.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE   4: Predicted;
DR   PRODOM; Q8IAX3.
DR   SWISS-2DPAGE; Q8IAX3.
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00434};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00434};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..1419
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004308150"
FT   DOMAIN          267..696
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000259|PROSITE:PS50893"
FT   DOMAIN          971..1277
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000259|PROSITE:PS50893"
FT   NP_BIND         299..306
FT                   /note="ATP"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00434"
FT   NP_BIND         1008..1015
FT                   /note="ATP"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00434"
FT   REGION          134..210
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          813..920
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          732..763
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1145..1165
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1327..1347
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1363..1383
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        138..209
FT                   /note="Acidic"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        813..829
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        841..879
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        880..912
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1419 AA;  170108 MW;  7E481EDAA8E3A0A8 CRC64;
     MFLELYFYLI LCCYISFNSS LQVKKNNQYF LNSSYNRKGT SRPSRRKKNS FINKLFLAEH
     VNTKKSTFRC YQQCKHKKNV ESGNDYMCDG VKKKRKKSGN NKKSDICHYD EDEEGIIAKP
     YYDDYHRENR NDIQYDINED NNYEESDEDE LEEDEYEEEL EEDEYDEESD QDEYDEESDQ
     DEYDEESDQD EYDEESDQDG YDEESNEDDL DEHLKERLMK RKSFYSKLFN IDDNEDKFNV
     LSPKYNMNIY NILEKNYDQN EENQIVLTIK NLNYEINNRK LITNLNLQLN KTECIGLIGN
     NGCGKTTLLN LIYENSDNKL KSFTLNNNIK KKEDAVSLNK FNLNTLSSSV KKNDFTLLYK
     ILSYMKNNGI ELSNLPTLIQ NKTIHNILQE DNKDENNHNN NNNNNNNNKN NELFYKNEVF
     YFKQNIHLLE NNNLTIFEKV LKFYDNTLEK YEILNYIEDN FGKYEKYDTI KIYGLKDNKR
     NDEIEKRNHD ITKEDIKNDS SDIFITELNK NDQKLLKKSC MSSNQFNNVD TYGASNVLKN
     NEEDFLKSEY FKLILKLYMH EKENIYKEIN NIKMNFNKYV NILNLKNFLN VKLCHLSNGY
     IIRVYLLLLL LSKSKLLLID EINNNLDIFN IFFIMNIFKY SLKYKKLAII LATHDFFLVS
     KLCNRILDFN KISGYDVDLS NMALLKKINK NNNHDDQDYG IYMDDMTNNR TNERKSNLTY
     FKGNYTDYLN NMKILFENRK KKKEELKKIL DQINSVISKS KKKKKNEFIQ PFVKKKEEEL
     KLYQNINSIL FDTKLDYQYL YYNLIYSNKK NTDTKARGKE KEKEKEKTMV TNLTFTNTQK
     KNMDTEREDE INEKVDYESY SSDTNENVEE KEKNEKQKQQ QQQQKQQQQQ KQQQQKQTEQ
     NVPEQNVPEQ KEQVDNNYDD DEDIKKFVYN KFNDVEGNMN KNILIDMSKK IKNNELIETG
     EKYGTNNMPL YEFENFSFYF LNKNNKKKYI FKNMNLNINS GENVLLLGKN GIGKSTLFKI
     LTNKYNFVLK EKENKLKEKK SIYVYGDNDD IMDTNFSNII NETNIENIKK NYNFEGTINC
     NFKNVLLTYF EQNMIKKLNA EINDYFKNLV EKVNYEPISF YNSYNKNDDM ISNENFCFYI
     LNKTKLLYNE KIDNIEEKIN KLLKIFFIDS NTSIKDKSGG EKVRILFLSL FLKKSNLLLL
     DEINNNLDIY LKNLLLNFLN YIYQGSYILT THDFYIIKNL NNIHKIIYIF DYQNIFTFYN
     VQDFIENFYN FILNSFNLCN AELKDHEYIQ KKRDKARLHN YSNYLNSQNI LQSNHLVQNN
     IHLSSPYDTK KNDLINSEEN IDQLNNSANY QKYLYDNYDY EILQFLKKQF EKDNNERKNY
     EQINIQEEIF QKKKINKKNF GGKGTSGKIK IKNWKRWKK
//

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