(data stored in SCRATCH zone)

SWISSPROT: Q8IAY9_PLAF7

ID   Q8IAY9_PLAF7            Unreviewed;       877 AA.
AC   Q8IAY9;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   08-MAY-2019, entry version 101.
DE   SubName: Full=Importin beta, putative {ECO:0000313|EMBL:CAD51221.1};
GN   ORFNames=PF3D7_0815200 {ECO:0000313|EMBL:CAD51221.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAD51221.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.,
RA   Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S.,
RA   Chan M.S., Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S.,
RA   Pertea M., Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B.,
RA   Martin D.M., Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A.,
RA   McFadden G.I., Cummings L.M., Subramanian G.M., Mungall C.,
RA   Venter J.C., Carucci D.J., Hoffman S.L., Newbold C., Davis R.W.,
RA   Fraser C.M., Barrell B.;
RT   "Genome sequence of the human malaria parasite Plasmodium
RT   falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C.,
RA   Chillingworth T., Christodoulou Z., Clark L., Clark R., Corton C.,
RA   Cronin A., Davies R.M., Davis P., Dear P., Dearden F., Doggett J.,
RA   Feltwell T., Goble A., Goodhead I., Gwilliam R., Hamlin N., Hance Z.,
RA   Harper D., Hauser H., Hornsby T., Holroyd S., Horrocks P.,
RA   Humphray S., Jagels K., James K.D., Johnson D., Kerhornou A.,
RA   Knights A., Konfortov B., Kyes S., Larke N., Lawson D., Lennard N.,
RA   Line A., Maddison M., Mclean J., Mooney P., Moule S., Murphy L.,
RA   Oliver K., Ormond D., Price C., Quail M.A., Rabbinowitsch E.,
RA   Rajandream M.A., Rutter S., Rutherford K.M., Sanders M., Simmonds M.,
RA   Seeger K., Sharp S., Smith R., Squares R., Squares S., Stevens K.,
RA   Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|SAAS:SAAS00704922}.
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DR   EMBL; AL844507; CAD51221.1; -; Genomic_DNA.
DR   RefSeq; XP_001349372.1; XM_001349336.1.
DR   SMR; Q8IAY9; -.
DR   PRIDE; Q8IAY9; -.
DR   EnsemblProtists; CAD51221; CAD51221; PF3D7_0815200.
DR   GeneDB; PF3D7_0815200.1:pep; -.
DR   GeneID; 2655268; -.
DR   KEGG; pfa:PF3D7_0815200; -.
DR   EuPathDB; PlasmoDB:PF3D7_0815200; -.
DR   HOGENOM; HOG000280930; -.
DR   InParanoid; Q8IAY9; -.
DR   KO; K14293; -.
DR   OMA; KNHLTSK; -.
DR   PhylomeDB; Q8IAY9; -.
DR   BioCyc; PLASMO:PF08_0069-MONOMER; -.
DR   Reactome; R-PFA-6798695; Neutrophil degranulation.
DR   Proteomes; UP000001450; Chromosome 8.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0031965; C:nuclear membrane; IBA:GO_Central.
DR   GO; GO:0034399; C:nuclear periphery; IBA:GO_Central.
DR   GO; GO:0005643; C:nuclear pore; ISS:GeneDB.
DR   GO; GO:0008139; F:nuclear localization sequence binding; ISS:GeneDB.
DR   GO; GO:0008565; F:protein transporter activity; IBA:GO_Central.
DR   GO; GO:0008536; F:Ran GTPase binding; IEA:InterPro.
DR   GO; GO:0006607; P:NLS-bearing protein import into nucleus; ISS:GeneDB.
DR   GO; GO:0006610; P:ribosomal protein import into nucleus; IBA:GO_Central.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR040122; Importin_beta.
DR   PANTHER; PTHR10527; PTHR10527; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   4: Predicted;
DR   PRODOM; Q8IAY9.
DR   SWISS-2DPAGE; Q8IAY9.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001450};
KW   Nucleus {ECO:0000256|SAAS:SAAS00704873};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450}.
FT   DOMAIN       24    104       Importin N-terminal.
FT                                {ECO:0000259|PROSITE:PS50166}.
SQ   SEQUENCE   877 AA;  99964 MW;  FF628DD58E3A2C67 CRC64;
     MESSNIGQIL YATVDPNINI RSEAENKLKL AKESNFVQYI NQLSNEFCKS ENDPYLRQIA
     GLLIKNAFTS KDNYESEEKA RTWLNFPEDI KMELKNNLLV LLSQQSDKIV IGTACQIISI
     IAKIELSHNK SSELLHKLVN NIIEKNAYTK KSSTVCLAYL TEDIADVCNE SKSKYAFTQP
     DLDLILTAII NSLCEPAEES THCANMKVLY NLMSFIEHNF KTQVERDIIM KTVIDGCKDT
     ERQSVQIAAY ECLINIVSYF YSYLDAYMYA IGPLTWVAIE SENERIAISA IEFWNTVCEE
     ETFIDQYELQ EGKKNHNIVK QAMVFLLPKI FNAMITQESE DIDIDAWTLS MASATFLALS
     AQLLKNDIVE PVISFVEENF IHEDWRRRDA AVLAYGSIME GPDTEKLKPL VEESVGQLSE
     VLRDPSVAVR DTAAWTIGKI TTYHSEIIYN VLGSYNDSNS LYGILLERLN DYPRVAANVC
     WVFNQLAVNK RTSYNKMTNS YVTDLDDSFC VLCKKLIDVS SREDSDIRNL REAAFNALNV
     VILSVSDNCL KYMIELLSHM MYLLTNTYLN PLTEEVKSLQ GYYCGTMQFI INRLGNQCKP
     FLKPIYLSIF RLFEIRTDIC EDALLACSAI INVMAEDFRE HLKTFLNVIF KGLKNVSETS
     TCKICIEMIS DICIPWTSEY EKEMEAILEC LWEALKTFGV HDSIKISILT VLGDIATALN
     RSFSKYLNFF ANILSETSKI TITSGSPDSD DWVNYVFELR DAILLTYSNI IYALIDGNEI
     NKLKPYIPNI LDFIELILIK EINHFNAQNF QNSVSLLGDL VHAYGYELIE NSKLTDLIIS
     VYGKIDILSS QGDEKCETCV SKIKWLKRIC NARLSQK
//

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