(data stored in ACNUC9543 zone)

SWISSPROT: Q8IB47_PLAF7

ID   Q8IB47_PLAF7            Unreviewed;       867 AA.
AC   Q8IB47;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   08-MAY-2019, entry version 111.
DE   SubName: Full=ATP-dependent RNA helicase DHX36, putative {ECO:0000313|EMBL:CAD51161.1};
DE            EC=3.6.4.13 {ECO:0000313|EMBL:CAD51161.1};
GN   ORFNames=PF3D7_0821300 {ECO:0000313|EMBL:CAD51161.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAD51161.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.,
RA   Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S.,
RA   Chan M.S., Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S.,
RA   Pertea M., Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B.,
RA   Martin D.M., Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A.,
RA   McFadden G.I., Cummings L.M., Subramanian G.M., Mungall C.,
RA   Venter J.C., Carucci D.J., Hoffman S.L., Newbold C., Davis R.W.,
RA   Fraser C.M., Barrell B.;
RT   "Genome sequence of the human malaria parasite Plasmodium
RT   falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C.,
RA   Chillingworth T., Christodoulou Z., Clark L., Clark R., Corton C.,
RA   Cronin A., Davies R.M., Davis P., Dear P., Dearden F., Doggett J.,
RA   Feltwell T., Goble A., Goodhead I., Gwilliam R., Hamlin N., Hance Z.,
RA   Harper D., Hauser H., Hornsby T., Holroyd S., Horrocks P.,
RA   Humphray S., Jagels K., James K.D., Johnson D., Kerhornou A.,
RA   Knights A., Konfortov B., Kyes S., Larke N., Lawson D., Lennard N.,
RA   Line A., Maddison M., Mclean J., Mooney P., Moule S., Murphy L.,
RA   Oliver K., Ormond D., Price C., Quail M.A., Rabbinowitsch E.,
RA   Rajandream M.A., Rutter S., Rutherford K.M., Sanders M., Simmonds M.,
RA   Seeger K., Sharp S., Smith R., Squares R., Squares S., Stevens K.,
RA   Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
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DR   EMBL; AL844507; CAD51161.1; -; Genomic_DNA.
DR   RefSeq; XP_001349312.1; XM_001349276.1.
DR   SMR; Q8IB47; -.
DR   EnsemblProtists; CAD51161; CAD51161; PF3D7_0821300.
DR   GeneDB; PF3D7_0821300.1:pep; -.
DR   GeneID; 2655493; -.
DR   KEGG; pfa:PF3D7_0821300; -.
DR   EuPathDB; PlasmoDB:PF3D7_0821300; -.
DR   HOGENOM; HOG000175261; -.
DR   InParanoid; Q8IB47; -.
DR   OMA; EAIMYNE; -.
DR   PhylomeDB; Q8IB47; -.
DR   Proteomes; UP000001450; Chromosome 8.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0034459; F:ATP-dependent 3'-5' RNA helicase activity; IBA:GO_Central.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; ISS:GeneDB.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR011709; DUF1605.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF04408; HA2; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
DR   PRODOM; Q8IB47.
DR   SWISS-2DPAGE; Q8IB47.
KW   ATP-binding {ECO:0000256|SAAS:SAAS01176619};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001450};
KW   Helicase {ECO:0000313|EMBL:CAD51161.1};
KW   Hydrolase {ECO:0000256|SAAS:SAAS01176622,
KW   ECO:0000313|EMBL:CAD51161.1};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS01176608};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450}.
FT   DOMAIN       14    198       Helicase ATP-binding.
FT                                {ECO:0000259|PROSITE:PS51192}.
FT   DOMAIN      303    528       Helicase C-terminal.
FT                                {ECO:0000259|PROSITE:PS51194}.
FT   COILED       46     66       {ECO:0000256|SAM:Coils}.
FT   COILED      349    369       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   867 AA;  101800 MW;  465879B8928B4DB3 CRC64;
     MRELPILKYK HEIKKLIKKN NLIIIKGETG CGKTTQVPQI INEIFFDKKE KKYDNIKHKN
     DEKKKRKEKK KMLISLPRRV ATITVAERVS KEMKRGDIGN YVGYTIRFKN VCSDKTRIKF
     VTDGILIREI MNDPLLKKYK FLILDEIHER SIRTDVLLGY TKILLQKRKK IKIILMSATF
     DINIFNQFFN NPPIITIPHK LHKITIYYPR RNIEDYILSV VSTILQIHFG NTSYSSEFEN
     DDDHRENKPN ELNELNKSNE QNELNESNEV NKEHDSYESN KTHDINEIDE QNNLQTDNIS
     MNNINEDIKK TEDKSLGDIL VFLPGQEEIE MVNIMLKEKL KIIYKGNLLN KLMKERNNYN
     NQNDFQNKIN NKFNTDDHIL NEICFHFGKT EIMPDKIYNM KILQLYSSLP NKKQKVIFEP
     VPPNTRKVIL STNIAETSVT IPNIKYVIDS GKVKIKYFDV NRGSNVLRVT QISKDSAIQR
     SGRAGREAPG QVYRIYTKEE YENMNPFLIP EIFRSDLTQI YLELKAMNIN NPLEFNFPEN
     PRKELFVHSA KMLFKINAID MNNNLTDLGK KLCLFPLNPI YANILLCSIE FNCIDEIATI
     VALLNCDSIF LNYNFYEDLD TLNNDSLDKK KNNNEQKKIV QKNSVEDSKE NINKLENYDK
     KKGKNNNLEP YDDDHDDNDN DSNNNDDDMG EKKMNDKNKL INVARRKLIH PDGDHLTLLH
     IFYLWQEADI KEKKHFCNIY ALNNEILQQV EKIKIQLLEI MKNKMKIEIP KKLHMHKWDQ
     ILICLCKACF FNIAKSTSNT NVYINLVNKT KIRIHPSSTL FNSYIKPTFI FYSDIVQTKR
     LYARIVTKIE ADWLLKYVSA KFQVAKS
//

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