(data stored in ACNUC7820 zone)

SWISSPROT: Q8VFJ5_MOUSE

ID   Q8VFJ5_MOUSE            Unreviewed;       315 AA.
AC   Q8VFJ5;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   30-AUG-2017, entry version 126.
DE   RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};
GN   Name=Olfr830 {ECO:0000313|Ensembl:ENSMUSP00000077903,
GN   ECO:0000313|MGI:MGI:3030664};
GN   ORFNames=mCG_141850 {ECO:0000313|EMBL:EDL25058.1};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1] {ECO:0000313|EMBL:AAL61194.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=11875048; DOI=10.1093/hmg/11.5.535;
RA   Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA   Trask B.J.;
RT   "Different evolutionary processes shaped the mouse and human olfactory
RT   receptor gene families.";
RL   Hum. Mol. Genet. 11:535-546(2002).
RN   [2] {ECO:0000313|EMBL:AAL61194.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=11802173; DOI=10.1038/nn800;
RA   Zhang X., Firestein S.;
RT   "The olfactory receptor gene superfamily of the mouse.";
RL   Nat. Neurosci. 5:124-133(2002).
RN   [3] {ECO:0000313|EMBL:EDL25058.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Mixed {ECO:0000313|EMBL:EDL25058.1};
RX   PubMed=12040188; DOI=10.1126/science.1069193;
RA   Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R.,
RA   Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A.,
RA   Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.,
RA   Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K.,
RA   Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J.,
RA   Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R.,
RA   Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H.,
RA   Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A.,
RA   Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A.,
RA   Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C.,
RA   Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C.,
RA   Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B.,
RA   Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E.,
RA   Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R.,
RA   Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C.,
RA   Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L.,
RA   Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S.,
RA   Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L.,
RA   Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R.,
RA   Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R.,
RA   Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J.,
RA   Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L.,
RA   Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C.,
RA   Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A.,
RA   Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H.,
RA   Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L.,
RA   Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M.,
RA   Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K.,
RA   Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S.,
RA   Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J.,
RA   Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G.,
RA   Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.;
RT   "A comparison of whole-genome shotgun-derived mouse chromosome 16 and
RT   the human genome.";
RL   Science 296:1661-1671(2002).
RN   [4] {ECO:0000313|EMBL:AAL61194.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Adams M.;
RL   Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
RN   [5] {ECO:0000313|EMBL:EDL25058.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Mixed {ECO:0000313|EMBL:EDL25058.1};
RA   Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN   [6] {ECO:0000313|Ensembl:ENSMUSP00000077903, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000077903,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
RA   She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
RA   Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
RA   Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
RA   Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
RA   Lindblad-Toh K., Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of
RT   the mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [7] {ECO:0000313|Ensembl:ENSMUSP00000077903}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000077903};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU363047, ECO:0000256|SAAS:SAAS00857205};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363047,
CC       ECO:0000256|SAAS:SAAS00857205}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000256|RuleBase:RU000688, ECO:0000256|SAAS:SAAS00857212}.
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DR   EMBL; AC154453; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AY073531; AAL61194.1; -; Genomic_DNA.
DR   EMBL; CH466522; EDL25058.1; -; Genomic_DNA.
DR   RefSeq; NP_666777.1; NM_146566.1.
DR   RefSeq; XP_006510417.1; XM_006510354.1.
DR   UniGene; Mm.377568; -.
DR   STRING; 10090.ENSMUSP00000077903; -.
DR   Ensembl; ENSMUST00000078861; ENSMUSP00000077903; ENSMUSG00000062868.
DR   GeneID; 258559; -.
DR   KEGG; mmu:258559; -.
DR   UCSC; uc009ogz.1; mouse.
DR   CTD; 258559; -.
DR   MGI; MGI:3030664; Olfr830.
DR   GeneTree; ENSGT00840000129792; -.
DR   HOGENOM; HOG000041364; -.
DR   HOVERGEN; HBG017625; -.
DR   KO; K04257; -.
DR   OMA; VVCTIFE; -.
DR   OrthoDB; EOG091G0B53; -.
DR   TreeFam; TF337210; -.
DR   Reactome; R-MMU-381753; Olfactory Signaling Pathway.
DR   Proteomes; UP000000589; Chromosome 9.
DR   Bgee; ENSMUSG00000062868; -.
DR   GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; IBA:GO_Central.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; ISA:MGI.
DR   GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q8VFJ5.
DR   SWISS-2DPAGE; Q8VFJ5.
KW   Cell membrane {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857207};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000589};
KW   G-protein coupled receptor {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857203};
KW   Membrane {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857208};
KW   Olfaction {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857209};
KW   Receptor {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857193, ECO:0000313|EMBL:AAL61194.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW   Sensory transduction {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857210};
KW   Transducer {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857213};
KW   Transmembrane {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857211};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857194}.
FT   TRANSMEM     29     50       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM     62     81       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    101    123       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    135    161       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    200    219       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    240    262       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    274    295       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   DOMAIN       44    293       G_PROTEIN_RECEP_F1_2.
FT                                {ECO:0000259|PROSITE:PS50262}.
SQ   SEQUENCE   315 AA;  35498 MW;  4750A4441D98AD3E CRC64;
     MSNMEVENKS VVLDIFLHGL TNDPELQPFI FVLFLSIYLI TVSGNLLIML AIKCDFHLHN
     PMYFFLCHLS FNDMYLISIT VPKMLMNIQT KDQRITFAGC LSQACFVVVC TIFECFLLGV
     MAYDRYIAIC YPLRYTVLMN PSFCVILVLF SLFFSIVNGL LHSLMVLYLS FCTDLEILHF
     FCEIAQILKL ACSDSLINNI LIFVTASIFA GLPLFAIIFS YTHIVSTVLK MPSSEGKYKA
     FSTCGSHLSV VSLFYGTGFG VYITSKVIDS PKKIAVASVM YSVVPPMLNP FVYCLRNRDM
     KEALKKVIGR TASLL
//

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