(data stored in ACNUC7820 zone)

SWISSPROT: Q8VGT4_MOUSE

ID   Q8VGT4_MOUSE            Unreviewed;       309 AA.
AC   Q8VGT4;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   30-AUG-2017, entry version 120.
DE   RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};
GN   Name=Olfr532 {ECO:0000313|EMBL:AAP71026.1,
GN   ECO:0000313|Ensembl:ENSMUSP00000072959, ECO:0000313|MGI:MGI:3030366};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1] {ECO:0000313|EMBL:AAL60725.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=11875048; DOI=10.1093/hmg/11.5.535;
RA   Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA   Trask B.J.;
RT   "Different evolutionary processes shaped the mouse and human olfactory
RT   receptor gene families.";
RL   Hum. Mol. Genet. 11:535-546(2002).
RN   [2] {ECO:0000313|EMBL:AAL60725.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=11802173; DOI=10.1038/nn800;
RA   Zhang X., Firestein S.;
RT   "The olfactory receptor gene superfamily of the mouse.";
RL   Nat. Neurosci. 5:124-133(2002).
RN   [3] {ECO:0000313|EMBL:AAL60725.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Adams M.;
RL   Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|EMBL:AAP71026.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=14611657; DOI=10.1186/gb-2003-4-11-r71;
RA   Young J.M., Shykind B.M., Lane R.P., Tonnes-Priddy L., Ross J.A.,
RA   Walker M., Williams E.M., Trask B.J.;
RT   "Odorant receptor expressed sequence tags demonstrate olfactory
RT   expression of over 400 genes, extensive alternate splicing and unequal
RT   expression levels.";
RL   Genome Biol. 4:R71.1-R71.13(2003).
RN   [5] {ECO:0000313|EMBL:AAP71026.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Sanders K.;
RL   Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
RN   [6] {ECO:0000313|Ensembl:ENSMUSP00000072959, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000072959,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
RA   She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
RA   Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
RA   Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
RA   Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
RA   Lindblad-Toh K., Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of
RT   the mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [7] {ECO:0000313|Ensembl:ENSMUSP00000072959}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000072959};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [8] {ECO:0000313|EMBL:ALI87894.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=C57BL/6 {ECO:0000313|EMBL:ALI87894.1};
RA   Mainland J.D., Li Y.R., Zhou T., Liu W.L.L., Matsunami H.;
RT   "Human Olfactory Receptor Responses to Odorants.";
RL   Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
RN   [9] {ECO:0000313|Ensembl:ENSMUSP00000150798}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000150798};
RG   Ensembl;
RL   Submitted (DEC-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU363047, ECO:0000256|SAAS:SAAS00857205};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363047,
CC       ECO:0000256|SAAS:SAAS00857205}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000256|RuleBase:RU000688, ECO:0000256|SAAS:SAAS00857212}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AC117670; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AY073062; AAL60725.1; -; Genomic_DNA.
DR   EMBL; AY317641; AAP71026.1; -; Genomic_DNA.
DR   EMBL; KP290736; ALI87894.1; -; Genomic_DNA.
DR   RefSeq; NP_667237.1; NM_147026.1.
DR   UniGene; Mm.377796; -.
DR   DNASU; 259028; -.
DR   Ensembl; ENSMUST00000073226; ENSMUSP00000072959; ENSMUSG00000063823.
DR   Ensembl; ENSMUST00000213801; ENSMUSP00000150798; ENSMUSG00000063823.
DR   GeneID; 259028; -.
DR   KEGG; mmu:259028; -.
DR   UCSC; uc009khr.1; mouse.
DR   CTD; 259028; -.
DR   MGI; MGI:3030366; Olfr532.
DR   eggNOG; ENOG410IVB2; Eukaryota.
DR   eggNOG; ENOG41114MW; LUCA.
DR   GeneTree; ENSGT00440000034500; -.
DR   HOGENOM; HOG000041364; -.
DR   HOVERGEN; HBG017625; -.
DR   OMA; IMAANNH; -.
DR   OrthoDB; EOG091G0AZH; -.
DR   TreeFam; TF340219; -.
DR   Proteomes; UP000000589; Chromosome 7.
DR   Bgee; ENSMUSG00000063823; -.
DR   GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005549; F:odorant binding; IBA:GO_Central.
DR   GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; ISA:MGI.
DR   GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   SMART; SM01381; 7TM_GPCR_Srsx; 1.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q8VGT4.
DR   SWISS-2DPAGE; Q8VGT4.
KW   Cell membrane {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857207};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000589};
KW   G-protein coupled receptor {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857203};
KW   Membrane {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857208};
KW   Olfaction {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857209};
KW   Receptor {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857193, ECO:0000313|EMBL:AAL60725.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW   Sensory transduction {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857210};
KW   Transducer {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857213};
KW   Transmembrane {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857211};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857194}.
FT   TRANSMEM     25     47       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM     59     78       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM     98    120       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    132    154       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    204    226       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    238    260       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    272    292       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   DOMAIN       41    290       G_PROTEIN_RECEP_F1_2.
FT                                {ECO:0000259|PROSITE:PS50262}.
SQ   SEQUENCE   309 AA;  34323 MW;  936C3E4B85A4B2C0 CRC64;
     MAINNSTTVV EFVLQGLSED PGLQALFLAF FLLLYILALA GNTLIIIAIS LNPRLHTPMY
     FFLANLALLD IICTSTVVPK LLEGLVGKSS HISYKGCMTQ VFFLIWVLGA ELLLLTAMAY
     DRYVAICRPL HYNTLMSWPI CVLLAGFVWV IGIANTSVHI GLLVRLNFCG SNQIRHFLCE
     VPTLLLLSCS PTTLNNIMLV IADVYFGVLN FLLTMISYSF IISSILRIRS AEGKKRAFST
     CSAHLVVVTL YYSTIIYTYL QPGSGSSFQN SKVVTLLYTA VSPTLNPIIY SLRNKDVKVA
     LKRLFPCFH
//

If you have problems or comments...

PBIL Back to PBIL home page