(data stored in SCRATCH zone)

SWISSPROT: Q8VIJ7_MOUSE

ID   Q8VIJ7_MOUSE            Unreviewed;       317 AA.
AC   Q8VIJ7;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   05-JUL-2017, entry version 93.
DE   SubName: Full=Retinol dehydrogenase type 1 {ECO:0000313|EMBL:AAK30001.1};
GN   Name=Rdh1 {ECO:0000313|EMBL:AAK30001.1, ECO:0000313|MGI:MGI:1195275};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|EMBL:AAK30001.1};
RN   [1] {ECO:0000313|EMBL:AAK30001.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=11562362; DOI=10.1074/jbc.M105748200;
RA   Zhang M., Chen W., Smith S.M., Napoli J.L.;
RT   "Molecular characterization of a mouse short chain
RT   dehydrogenase/reductase active with all-trans-retinol in intact cells,
RT   mRDH1.";
RL   J. Biol. Chem. 276:44083-44090(2001).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases
CC       (SDR) family. {ECO:0000256|RuleBase:RU000363}.
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DR   EMBL; AY028928; AAK30001.1; -; mRNA.
DR   RefSeq; NP_536684.2; NM_080436.3.
DR   UniGene; Mm.484271; -.
DR   ProteinModelPortal; Q8VIJ7; -.
DR   IntAct; Q8VIJ7; 1.
DR   MINT; MINT-4120386; -.
DR   PaxDb; Q8VIJ7; -.
DR   PeptideAtlas; Q8VIJ7; -.
DR   GeneID; 107605; -.
DR   KEGG; mmu:107605; -.
DR   CTD; 107605; -.
DR   MGI; MGI:1195275; Rdh1.
DR   eggNOG; KOG1610; Eukaryota.
DR   eggNOG; ENOG410Y7FK; LUCA.
DR   HOVERGEN; HBG005482; -.
DR   BRENDA; 1.1.1.105; 3474.
DR   Genevisible; Q8VIJ7; MM.
DR   GO; GO:0004745; F:retinol dehydrogenase activity; IDA:MGI.
DR   GO; GO:0016229; F:steroid dehydrogenase activity; IDA:MGI.
DR   GO; GO:0001523; P:retinoid metabolic process; IDA:MGI.
DR   GO; GO:0008202; P:steroid metabolic process; IDA:MGI.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   InterPro; IPR002347; SDR_fam.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; Q8VIJ7.
DR   SWISS-2DPAGE; Q8VIJ7.
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     17       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        18    317       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5004316923.
SQ   SEQUENCE   317 AA;  35914 MW;  CBFFB3FAEF7CD2DA CRC64;
     MWLYLVALVG LWTLLRFFRE RQVVSHLQVK YVFITGCDSG FGNLLARQLD RRGMRVLAAC
     LTEKGAEELR NKTSDRLETV ILDVTKTESI VAATQWVKER VGNRGLWGLV NNAGISTPSG
     PNEWMKKQDF ARVLDVNLLG MIEVTLSMLP LVRKARGRVV NVSSVMGRMS FFGGGYCISK
     YGVEAFSDSL RRELSYFGVK VAIIEPGGFK TCVTSSDRLS SNTKMIWDKA SSEVKEIYGE
     KFLLFYLKNL NELDKRCNKD LSVVTDCMEH ALTARHPRTR YSAGWDAKFL FLPLSYLPTF
     LVDALLYWTS MKPEKAL
//

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