(data stored in SCRATCH zone)

SWISSPROT: Q8X4M4_ECO57

ID   Q8X4M4_ECO57            Unreviewed;       417 AA.
AC   Q8X4M4; Q7AH59;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   05-JUL-2017, entry version 117.
DE   SubName: Full=Galactoside permease {ECO:0000313|EMBL:BAB33819.1};
DE   SubName: Full=Galactoside permease (M protein) {ECO:0000313|EMBL:AAG54692.1};
GN   Name=lacY {ECO:0000313|EMBL:AAG54692.1};
GN   OrderedLocusNames=ECs0396 {ECO:0000313|EMBL:BAB33819.1}, Z0439
GN   {ECO:0000313|EMBL:AAG54692.1};
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334 {ECO:0000313|Proteomes:UP000002519};
RN   [1] {ECO:0000313|EMBL:BAB33819.1, ECO:0000313|Proteomes:UP000000558}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC
RC   {ECO:0000313|Proteomes:UP000000558}, and Sakai
RC   {ECO:0000313|EMBL:BAB33819.1};
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
RN   [2] {ECO:0000313|EMBL:AAG54692.1, ECO:0000313|Proteomes:UP000002519}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EDL933 {ECO:0000313|EMBL:AAG54692.1}, and O157:H7 / EDL933 /
RC   ATCC 700927 / EHEC {ECO:0000313|Proteomes:UP000002519};
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G.III., Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
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DR   EMBL; AE005174; AAG54692.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33819.1; -; Genomic_DNA.
DR   PIR; D90678; D90678.
DR   PIR; H85528; H85528.
DR   RefSeq; NP_308423.1; NC_002695.1.
DR   RefSeq; WP_000291541.1; NZ_MWVM01000022.1.
DR   STRING; 155864.Z0439; -.
DR   EnsemblBacteria; AAG54692; AAG54692; Z0439.
DR   EnsemblBacteria; BAB33819; BAB33819; BAB33819.
DR   GeneID; 914498; -.
DR   KEGG; ece:Z0439; -.
DR   KEGG; ecs:ECs0396; -.
DR   PATRIC; fig|386585.9.peg.491; -.
DR   eggNOG; ENOG4105U0F; Bacteria.
DR   eggNOG; ENOG410XQTD; LUCA.
DR   HOGENOM; HOG000114363; -.
DR   KO; K02532; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006810; P:transport; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR000576; LacY/RafB_perm_fam.
DR   InterPro; IPR018457; LacY/RafB_perm_fam_CS.
DR   InterPro; IPR020846; MFS_dom.
DR   Pfam; PF01306; LacY_symp; 1.
DR   PRINTS; PR00174; LACYSMPORT.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00882; 2A0105; 1.
DR   PROSITE; PS00896; LACY_1; 1.
DR   PROSITE; PS00897; LACY_2; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   4: Predicted;
DR   PRODOM; Q8X4M4.
DR   SWISS-2DPAGE; Q8X4M4.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000558,
KW   ECO:0000313|Proteomes:UP000002519};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     12     34       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     46     66       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     75     95       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    101    122       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    143    162       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    168    187       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    222    239       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    259    279       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    349    369       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    381    401       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        8    404       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   417 AA;  46517 MW;  791EDD44E5C4AEBB CRC64;
     MYYLKNTNFW MFGLFFFFYF FIMGAYFPFF PIWLHDINHI SKSDTGIIFA AISLFSLLFQ
     PLFGLLSDKL GLRKYLLWII TGMLVMFAPF FIFIFGPLLQ YNILVGSIVG GIYLGFCFNA
     GAPAVEAFIE KVSRRSNFEF GRARMFGCVG WALCASIVGI MFTINNQFVF WLGSGCALIL
     AILLFFAKTD APSSATVANA VGANHSAFSL KLALELFRQP KLWFLSLYVI GVSCTYDVFD
     QQFANFFTSF FATGEQGTRV FGYVTTMGEL LNASIMFFAP LIINRIGGKN ALLLAGTIMS
     VRIIGSSFAT SALEVVILKT LHMFEVPFLL VGCFKYITSQ FEVRFSATIY LVCFCFFKQL
     AMIFMSVLAG NMYESIGFQG AYLVLGLVAL GFTLISVFTL SGPGPLSLLR RQVNEVA
//

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