(data stored in SCRATCH zone)

SWISSPROT: Q8X698_ECO57

ID   Q8X698_ECO57            Unreviewed;       528 AA.
AC   Q8X698; Q7AH68;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   05-JUL-2017, entry version 134.
DE   SubName: Full=Regulator for prp operon {ECO:0000313|EMBL:AAG54679.1};
GN   Name=prpR {ECO:0000313|EMBL:AAG54679.1};
GN   OrderedLocusNames=ECs0384 {ECO:0000313|EMBL:BAB33807.1}, Z0426
GN   {ECO:0000313|EMBL:AAG54679.1};
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334 {ECO:0000313|Proteomes:UP000002519};
RN   [1] {ECO:0000313|EMBL:BAB33807.1, ECO:0000313|Proteomes:UP000000558}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC
RC   {ECO:0000313|Proteomes:UP000000558}, and Sakai
RC   {ECO:0000313|EMBL:BAB33807.1};
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
RN   [2] {ECO:0000313|EMBL:AAG54679.1, ECO:0000313|Proteomes:UP000002519}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EDL933 {ECO:0000313|EMBL:AAG54679.1}, and O157:H7 / EDL933 /
RC   ATCC 700927 / EHEC {ECO:0000313|Proteomes:UP000002519};
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G.III., Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AE005174; AAG54679.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33807.1; -; Genomic_DNA.
DR   PIR; C85527; C85527.
DR   PIR; H90676; H90676.
DR   RefSeq; NP_308411.1; NC_002695.1.
DR   RefSeq; WP_000941052.1; NZ_MWVM01000022.1.
DR   STRING; 155864.Z0426; -.
DR   EnsemblBacteria; AAG54679; AAG54679; Z0426.
DR   EnsemblBacteria; BAB33807; BAB33807; BAB33807.
DR   GeneID; 914486; -.
DR   KEGG; ece:Z0426; -.
DR   KEGG; ecs:ECs0384; -.
DR   PATRIC; fig|386585.9.peg.478; -.
DR   eggNOG; ENOG4108ET5; Bacteria.
DR   eggNOG; COG1221; LUCA.
DR   HOGENOM; HOG000058487; -.
DR   KO; K02688; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   GO; GO:0019629; P:propionate catabolic process, 2-methylcitrate cycle; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR009057; Homeobox-like.
DR   InterPro; IPR002197; HTH_Fis.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR012704; Sig_transdc_resp-reg_PrpR.
DR   InterPro; IPR010524; Sig_transdc_resp-reg_PrpR_N.
DR   InterPro; IPR002078; Sigma_54_int.
DR   InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR   InterPro; IPR025944; Sigma_54_int_dom_CS.
DR   Pfam; PF02954; HTH_8; 1.
DR   Pfam; PF06506; PrpR_N; 1.
DR   Pfam; PF00158; Sigma54_activat; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02329; propionate_PrpR; 1.
DR   PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR   PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR   PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE   4: Predicted;
DR   PRODOM; Q8X698.
DR   SWISS-2DPAGE; Q8X698.
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00193,
KW   ECO:0000256|SAAS:SAAS00110192};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000558,
KW   ECO:0000313|Proteomes:UP000002519};
KW   DNA-binding {ECO:0000256|SAAS:SAAS00814512};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00193,
KW   ECO:0000256|SAAS:SAAS00110083};
KW   Transcription {ECO:0000256|PROSITE-ProRule:PRU00193,
KW   ECO:0000256|SAAS:SAAS00814760};
KW   Transcription regulation {ECO:0000256|PROSITE-ProRule:PRU00193,
KW   ECO:0000256|SAAS:SAAS00814754}.
FT   DOMAIN      218    460       Sigma-54 factor interaction.
FT                                {ECO:0000259|PROSITE:PS50045}.
FT   NP_BIND     246    253       ATP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00193}.
FT   NP_BIND     318    327       ATP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00193}.
SQ   SEQUENCE   528 AA;  58629 MW;  30126CB7E4BECAA5 CRC64;
     MAHPPRLNDD KPVIWTVSVT RLFELFRDIS LEFDHLANIT PIQLGFEKAV TYIRKKLANE
     RCDAIIAAGS NGAYLKSRLS VPVILIKPSG YDVLQALAKA GKLTSSIGVV TYQETIPALV
     AFQKTFNLRL DQRSYITEED ARGQINELKA NGTEAVVGAG LITDLAEEAG MTGIFIYSAA
     TVRQAFSDAL DMTRMSLRHN THDATRNALR TRYVLGDMLG QSPQMEQVRQ TILLYARSSA
     AVLIEGETGT GKELAAQAIH REYFARHDAR QGKKSHPFVA VNCGAIAESL LEAELFGYEE
     GAFTGSRRGG RAGLFEIAHG GTLFLDEIGE MPLPLQTRLL RVLEEKEVTR VGGHQPVPVD
     VRVISATHCN LEEDMRQGQF RRDLFYRLSI LRLQLPPLRE RVADILPLAE SFLKVSLAAL
     SAPFSAALRQ GLQASETVLV HYDWPGNIRE LRNMMERLAL FLSVEPTPDL TPQFLQLLLP
     ELARESAKIP APRLLTPQQA LEKFNGDKTA AANYLGISRT TFWRRLKS
//

If you have problems or comments...

PBIL Back to PBIL home page