(data stored in SCRATCH zone)

SWISSPROT: Q8XE63_ECO57

ID   Q8XE63_ECO57            Unreviewed;       315 AA.
AC   Q8XE63; Q7AH04;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   05-JUL-2017, entry version 122.
DE   RecName: Full=Ubiquinol oxidase subunit 2 {ECO:0000256|PIRNR:PIRNR000292};
GN   Name=cyoA {ECO:0000313|EMBL:AAG54782.1};
GN   OrderedLocusNames=ECs0486 {ECO:0000313|EMBL:BAB33909.1}, Z0535
GN   {ECO:0000313|EMBL:AAG54782.1};
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334 {ECO:0000313|Proteomes:UP000002519};
RN   [1] {ECO:0000313|EMBL:BAB33909.1, ECO:0000313|Proteomes:UP000000558}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC
RC   {ECO:0000313|Proteomes:UP000000558}, and Sakai
RC   {ECO:0000313|EMBL:BAB33909.1};
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
RN   [2] {ECO:0000313|EMBL:AAG54782.1, ECO:0000313|Proteomes:UP000002519}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EDL933 {ECO:0000313|EMBL:AAG54782.1}, and O157:H7 / EDL933 /
RC   ATCC 700927 / EHEC {ECO:0000313|Proteomes:UP000002519};
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G.III., Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|PIRNR:PIRNR000292}.
CC   -!- SIMILARITY: Belongs to the cytochrome c oxidase subunit 2 family.
CC       {ECO:0000256|PIRNR:PIRNR000292}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AE005174; AAG54782.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33909.1; -; Genomic_DNA.
DR   PIR; B85540; B85540.
DR   PIR; F90689; F90689.
DR   RefSeq; NP_308513.1; NC_002695.1.
DR   RefSeq; WP_001239429.1; NZ_MWVM01000009.1.
DR   ProteinModelPortal; Q8XE63; -.
DR   STRING; 155864.Z0535; -.
DR   EnsemblBacteria; AAG54782; AAG54782; Z0535.
DR   EnsemblBacteria; BAB33909; BAB33909; BAB33909.
DR   GeneID; 914588; -.
DR   KEGG; ece:Z0535; -.
DR   KEGG; ecs:ECs0486; -.
DR   PATRIC; fig|386585.9.peg.587; -.
DR   eggNOG; ENOG4105E2S; Bacteria.
DR   eggNOG; COG1622; LUCA.
DR   HOGENOM; HOG000084157; -.
DR   KO; K02297; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-UniRule.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0008827; F:cytochrome o ubiquinol oxidase activity; IEA:InterPro.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0022900; P:electron transport chain; IEA:InterPro.
DR   CDD; cd04212; CuRO_UO_II; 1.
DR   Gene3D; 2.60.40.420; -; 1.
DR   InterPro; IPR002429; CcO_II-like_C.
DR   InterPro; IPR010514; COX_ARM.
DR   InterPro; IPR008972; Cupredoxin.
DR   InterPro; IPR034227; CuRO_UO_II.
DR   InterPro; IPR011759; Cyt_c_oxidase_su2_TM_dom.
DR   InterPro; IPR006333; Cyt_o_ubiquinol_oxidase_su2.
DR   Pfam; PF00116; COX2; 1.
DR   Pfam; PF06481; COX_ARM; 1.
DR   PIRSF; PIRSF000292; Ubi_od_II; 1.
DR   SUPFAM; SSF49503; SSF49503; 1.
DR   SUPFAM; SSF81464; SSF81464; 1.
DR   TIGRFAMs; TIGR01433; CyoA; 1.
DR   PROSITE; PS50857; COX2_CUA; 1.
DR   PROSITE; PS50999; COX2_TM; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q8XE63.
DR   SWISS-2DPAGE; Q8XE63.
KW   Cell membrane {ECO:0000256|PIRNR:PIRNR000292};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000558,
KW   ECO:0000313|Proteomes:UP000002519};
KW   Electron transport {ECO:0000256|PIRNR:PIRNR000292};
KW   Membrane {ECO:0000256|PIRNR:PIRNR000292, ECO:0000256|SAM:Phobius};
KW   Oxidoreductase {ECO:0000256|PIRNR:PIRNR000292};
KW   Respiratory chain {ECO:0000256|PIRNR:PIRNR000292};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|PIRNR:PIRNR000292}.
FT   TRANSMEM     43     67       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     88    108       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       21    118       COX2_TM. {ECO:0000259|PROSITE:PS50999}.
FT   DOMAIN      124    237       COX2_CUA. {ECO:0000259|PROSITE:PS50857}.
SQ   SEQUENCE   315 AA;  34930 MW;  E30B675D53D7D91C CRC64;
     MRLRKYNKSL GWLSLFAGTV LLSGCNSALL DPKGQIGLEQ RSLILTAFGL MLIVVIPAIL
     MAVGFAWKYR ASNKDAKYSP NWSHSNKVEA VVWTVPILII IFLAVLTWKT THALEPSKPL
     AHDEKPITIE VVSMDWKWFF IYPEQGFATV NEIAFPANTP VYFKVTSNSV MNSFFIPRLG
     SQIYAMAGMQ TRLHLIANEP GTYDGISASY SGPGFSGMKF KAIATPDRAA FDQWVAKAKQ
     SPNSMSDMAA FEKLAAPSEY NQVEYFSNVK PNLFADVINK FMAHGKSMDM TQPEGEHSAH
     EGMEGMDMSH AESAH
//

If you have problems or comments...

PBIL Back to PBIL home page