(data stored in SCRATCH zone)

SWISSPROT: Q9EWE9_STRCO

ID   Q9EWE9_STRCO            Unreviewed;       226 AA.
AC   Q9EWE9;
DT   01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2001, sequence version 1.
DT   08-MAY-2019, entry version 119.
DE   SubName: Full=Putative regulatory protein {ECO:0000313|EMBL:CAD30929.1};
GN   OrderedLocusNames=SCO4942 {ECO:0000313|EMBL:CAD30929.1};
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226 {ECO:0000313|Proteomes:UP000001973};
RN   [1] {ECO:0000313|EMBL:CAD30929.1, ECO:0000313|Proteomes:UP000001973}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145
RC   {ECO:0000313|Proteomes:UP000001973};
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H.,
RA   Harper D., Bateman A., Brown S., Chandra G., Chen C.W., Collins M.,
RA   Cronin A., Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S.,
RA   Huang C.H., Kieser T., Larke L., Murphy L., Oliver K., O'Neil S.,
RA   Rabbinowitsch E., Rajandream M.A., Rutherford K., Rutter S.,
RA   Seeger K., Saunders D., Sharp S., Squares R., Squares S., Taylor K.,
RA   Warren T., Wietzorrek A., Woodward J., Barrell B.G., Parkhill J.,
RA   Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces
RT   coelicolor A3(2).";
RL   Nature 417:141-147(2002).
RN   [2] {ECO:0000213|PDB:2PZ9}
RP   X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS).
RX   PubMed=17982461; DOI=10.1038/nmeth1118;
RA   Dong A., Xu X., Edwards A.M., Chang C., Chruszcz M., Cuff M.,
RA   Cymborowski M., Di Leo R., Egorova O., Evdokimova E., Filippova E.,
RA   Gu J., Guthrie J., Ignatchenko A., Joachimiak A., Klostermann N.,
RA   Kim Y., Korniyenko Y., Minor W., Que Q., Savchenko A., Skarina T.,
RA   Tan K., Yakunin A., Yee A., Yim V., Zhang R., Zheng H., Akutsu M.,
RA   Arrowsmith C., Avvakumov G.V., Bochkarev A., Dahlgren L.G.,
RA   Dhe-Paganon S., Dimov S., Dombrovski L., Finerty P., Flodin S.,
RA   Flores A., Graslund S., Hammerstrom M., Herman M.D., Hong B.S.,
RA   Hui R., Johansson I., Liu Y., Nilsson M., Nedyalkova L., Nordlund P.,
RA   Nyman T., Min J., Ouyang H., Park H.W., Qi C., Rabeh W., Shen L.,
RA   Shen Y., Sukumard D., Tempel W., Tong Y., Tresagues L., Vedadi M.,
RA   Walker J.R., Weigelt J., Welin M., Wu H., Xiao T., Zeng H., Zhu H.;
RT   "In situ proteolysis for protein crystallization and structure
RT   determination.";
RL   Nat. Methods 4:1019-1021(2007).
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DR   EMBL; AL939122; CAD30929.1; -; Genomic_DNA.
DR   RefSeq; NP_629094.1; NC_003888.3.
DR   RefSeq; WP_011029965.1; NC_003888.3.
DR   PDB; 2PZ9; X-ray; 2.80 A; A=1-226.
DR   PDBsum; 2PZ9; -.
DR   SMR; Q9EWE9; -.
DR   STRING; 100226.SCO4942; -.
DR   EnsemblBacteria; CAD30929; CAD30929; CAD30929.
DR   GeneID; 1100383; -.
DR   KEGG; sco:SCO4942; -.
DR   PATRIC; fig|100226.15.peg.5022; -.
DR   eggNOG; ENOG4105KMP; Bacteria.
DR   eggNOG; ENOG4111UGD; LUCA.
DR   HOGENOM; HOG000161261; -.
DR   InParanoid; Q9EWE9; -.
DR   OMA; HFRDKET; -.
DR   PhylomeDB; Q9EWE9; -.
DR   EvolutionaryTrace; Q9EWE9; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   InterPro; IPR041467; Sco4008_C.
DR   InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR   Pfam; PF17926; TetR_C_21; 1.
DR   Pfam; PF00440; TetR_N; 1.
DR   PRINTS; PR00455; HTHTETR.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF48498; SSF48498; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   1: Evidence at protein level;
DR   PRODOM; Q9EWE9.
DR   SWISS-2DPAGE; Q9EWE9.
KW   3D-structure {ECO:0000213|PDB:2PZ9};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001973};
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335,
KW   ECO:0000256|SAAS:SAAS00132209};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001973};
KW   Transcription {ECO:0000256|SAAS:SAAS00131596};
KW   Transcription regulation {ECO:0000256|SAAS:SAAS00132066}.
FT   DOMAIN       29     89       HTH tetR-type. {ECO:0000259|PROSITE:
FT                                PS50977}.
FT   DNA_BIND     52     71       H-T-H motif. {ECO:0000256|PROSITE-
FT                                ProRule:PRU00335}.
SQ   SEQUENCE   226 AA;  24517 MW;  503F76A0AFD1A83A CRC64;
     MVAYPGPMPR SPSPGQTPDA PTSGGGSTDS TRQRIVAAAK EEFARHGIAG ARVDRIAKQA
     RTSKERVYAY FRSKEALYAH VAERETTALI EATQLDPADL PGYAGILFDH FAARPDHYRL
     ITWGRLELAE SADNTSGPLQ ATIAGKLDKL RDAQRIGLLD PAWDPVDVLA LINQIAMTWA
     GQPEIAAAAA DQAVDPSVTA RRAALVTAVE HMFPRPDRDQ RPNRLT
//

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