(data stored in ACNUC10043 zone)

SWISSPROT: IF2B_AERPE

ID   IF2B_AERPE              Reviewed;         148 AA.
AC   Q9YBR6;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   26-JUN-2007, sequence version 3.
DT   11-DEC-2019, entry version 91.
DE   RecName: Full=Translation initiation factor 2 subunit beta;
DE   AltName: Full=aIF2-beta;
DE   AltName: Full=eIF-2-beta;
GN   Name=eif2b; OrderedLocusNames=APE_1533.1;
OS   Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 /
OS   K1).
OC   Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales;
OC   Desulfurococcaceae; Aeropyrum.
OX   NCBI_TaxID=272557;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1;
RX   PubMed=10382966; DOI=10.1093/dnares/6.2.83;
RA   Kawarabayasi Y., Hino Y., Horikawa H., Yamazaki S., Haikawa Y., Jin-no K.,
RA   Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A.,
RA   Fukui S., Nagai Y., Nishijima K., Nakazawa H., Takamiya M., Masuda S.,
RA   Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A.,
RA   Aoki K., Kubota K., Nakamura Y., Nomura N., Sako Y., Kikuchi H.;
RT   "Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon,
RT   Aeropyrum pernix K1.";
RL   DNA Res. 6:83-101(1999).
CC   -!- FUNCTION: eIF-2 functions in the early steps of protein synthesis by
CC       forming a ternary complex with GTP and initiator tRNA. {ECO:0000250}.
CC   -!- SUBUNIT: Heterotrimer composed of an alpha, a beta and a gamma chain.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the eIF-2-beta/eIF-5 family. {ECO:0000305}.
DR   EMBL; BA000002; BAA80532.2; -; Genomic_DNA.
DR   PIR; F72634; F72634.
DR   SMR; Q9YBR6; -.
DR   STRING; 272557.APE_1533.1; -.
DR   PRIDE; Q9YBR6; -.
DR   EnsemblBacteria; BAA80532; BAA80532; APE_1533.1.
DR   KEGG; ape:APE_1533.1; -.
DR   eggNOG; arCOG01640; Archaea.
DR   eggNOG; COG1601; LUCA.
DR   HOGENOM; HOG000107197; -.
DR   KO; K03238; -.
DR   Proteomes; UP000002518; Chromosome.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00232; eIF_2_beta; 1.
DR   InterPro; IPR004458; TIF2_bsu_arc.
DR   InterPro; IPR002735; Transl_init_fac_IF2/IF5.
DR   InterPro; IPR016189; Transl_init_fac_IF2/IF5_N.
DR   InterPro; IPR016190; Transl_init_fac_IF2/IF5_Zn-bd.
DR   Pfam; PF01873; eIF-5_eIF-2B; 1.
DR   SMART; SM00653; eIF2B_5; 1.
DR   SUPFAM; SSF100966; SSF100966; 1.
DR   SUPFAM; SSF75689; SSF75689; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q9YBR6.
DR   SWISS-2DPAGE; Q9YBR6.
KW   Initiation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..148
FT                   /note="Translation initiation factor 2 subunit beta"
FT                   /id="PRO_0000137416"
SQ   SEQUENCE   148 AA;  16978 MW;  D5A9E73BA8AD36E6 CRC64;
     MSGSVLDEEA EKLMDYDYLL EKLYKKVPPK SGTSEYRIPE PQIIRIGSQT VIRNFREIAQ
     ALKRDPKLVA RYLQKELATA ASYEEESGQL ILNVKVSRKV VNQFLQLFMK TYVRCPTCGS
     IDTKLLRQER AYMLKCEACG AEQPVKPI
//

If you have problems or comments...

PBIL Back to PBIL home page