(data stored in SCRATCH zone)

EMBL: U12170

ID   U12170; SV 1; linear; mRNA; STD; HUM; 3952 BP.
XX
AC   U12170;
XX
DT   22-AUG-1994 (Rel. 40, Created)
DT   21-OCT-2008 (Rel. 97, Last updated, Version 8)
XX
DE   Human zinc finger homeodomain protein mRNA, complete cds.
XX
KW   .
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RA   Bachman N.J., Scarpulla R.C.;
RT   "A human zinc finger homeodomain protein homologous to the chicken
RT   delta-crystallin enhancer binding protein, delta EF1";
RL   Unpublished.
XX
RN   [2]
RP   22-3515
RX   PUBMED; 8138542.
RA   Watanabe Y., Kawakami K., Hirayama Y., Nagano K.;
RT   "Transcription factors positively and negatively regulating the Na,K-ATPase
RT   alpha 1 subunit gene";
RL   J. Biochem. 114(6):849-855(1993).
XX
RN   [3]
RP   1090-3605
RX   DOI; 10.1126/science.1840704.
RX   PUBMED; 1840704.
RA   Williams T.M., Moolten D., Burlein J., Romano J., Bhaerman R., Godillot A.,
RA   Mellon M., Rauscher F.J.III., Kant J.A.;
RT   "Identification of a zinc finger protein that inhibits IL-2 gene
RT   expression";
RL   Science 254(5039):1791-1794(1991).
XX
RN   [4]
RP   1-3952
RA   Bachman N.J.;
RT   ;
RL   Submitted (11-JUL-1994) to the INSDC.
RL   Nancy J. Bachman, CMS Biology, Northwestern University Medical School, 303
RL   E. Chicago Ave., Chicago, IL 60611, USA
XX
DR   Ensembl-Gn; ENSG00000148516; homo_sapiens.
DR   Ensembl-Tr; ENST00000320985; homo_sapiens.
DR   Ensembl-Tr; ENST00000361642; homo_sapiens.
DR   EuropePMC; PMC162233; 12832491.
DR   EuropePMC; PMC18613; 10841546.
DR   EuropePMC; PMC2227948; 18237449.
DR   EuropePMC; PMC3196287; 22016835.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..3952
FT                   /organism="Homo sapiens"
FT                   /mol_type="mRNA"
FT                   /clone_lib="lambda gt11 Clontech #HL1022"
FT                   /cell_line="HeLa"
FT                   /db_xref="taxon:9606"
FT   5'UTR           1..24
FT   CDS_pept        25..3399
FT                   /codon_start=1
FT                   /product="zinc finger homeodomain protein"
FT                   /note="encodes 7 zinc fingers; an amino terminal cluster
FT                   (fingers 1-4; aa 172..292) and a carboxy terminal cluster
FT                   (fingers 5-7; aa 906..981); homeodomain is also present (aa
FT                   58..640); similar to chicken delta-crystallin enhancer
FT                   binding protein deltaEF1: SwissProt Accession Number
FT                   P36197"
FT                   /db_xref="GOA:P37275"
FT                   /db_xref="H-InvDB:HIT000218075.14"
FT                   /db_xref="HGNC:HGNC:11642"
FT                   /db_xref="InterPro:IPR001356"
FT                   /db_xref="InterPro:IPR007087"
FT                   /db_xref="InterPro:IPR008598"
FT                   /db_xref="InterPro:IPR009057"
FT                   /db_xref="InterPro:IPR013087"
FT                   /db_xref="InterPro:IPR015880"
FT                   /db_xref="PDB:2E19"
FT                   /db_xref="UniProtKB/Swiss-Prot:P37275"
FT                   /citation=[2]
FT                   /protein_id="AAA20602.1"
FT                   /translation="MADGPRCKRRKQANPRRNNVTNYNTVVETNSDSDDEDKLHIVEEE
FT                   SVTDAADCEGVPEDDLPTDQTVLPGRSSEREGNAKNCWEDDRKEGQEILGPEAQADEAG
FT                   CTVKDDECESDAENEQNHDPNVEEFLQQQDTAVIFPEAPEEDQRQGTPEASGHDENGTP
FT                   DAFSQLLTCPYCDRGYKRFTSLKEHIKYRHEKNEDNFSCSLCSYTFAYRTQLERHMTSH
FT                   KSGRDQRHVTQSGCNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSG
FT                   SYSSHISSKKCISLIPVNGRPRTGLKTSQCSSPSLSASPGSPTRPQIRQKIENKPLQEQ
FT                   LSVNQIKTEPVDYEFKPIVVASGINCSTPLQNGVFTGGGPLQATSSPQGMVQAVVLPTV
FT                   GLVSPISINLSDIQNVLKVAIDGNVIRQVLENNQANLASKEQETINASPIQQGGHSVIS
FT                   AISLPLVDQDGTTKIIINYSLEQPSQLQVVPQNLKKENPVATNSCKSEKLPEDLTVKSE
FT                   KDKSFEGGVNDSTCLLCDDCPGDINALPELKHYDLKQPTQPPPLPAAEAEKPESSVSSA
FT                   TGDGNLSPSQPPLKNLLSLLKAYYALNAQPSAEELSKIADSVNLPLDVVKKWFEKMQAG
FT                   QISVQSSEPSSPEPGKVNTPAKNNDQPQSANANEPQDSTVNLQSPLKMTNSPVLPVGST
FT                   TNGSRSSTPSPSPLNLSSSRNTQGYLYTAEGAQEEPQVEPLDLSLPKQQGELLERSTIT
FT                   SVYQNSVYSVQEEPLNLSCAKKEPQKDSCVTDSEPVVNVIPPSANPINIAIPTVTAQLP
FT                   TIVAIADQNSVPCLRALAANKQTILIPQVAYTYSTTVSPAVQEPPLKVIQPNGNQDERQ
FT                   DTSSEGVSNVEDQNDSDSTPPKKKMRKTENGMYACDLCDKIFQKSSSLLRHKYEHTGKR
FT                   PHECGICKKAFKHKHHLIEHMRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKRE
FT                   AEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERESLTREEDEDSEKEEEEEDKEME
FT                   ELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTEGLMKDDRAESQASSLGQ
FT                   KVGESSEQVSEEKTNEA"
FT   3'UTR           3400..>3952
FT                   /citation=[2]
FT                   /citation=[3]
FT   repeat_region   3549..3592
FT                   /rpt_family="AC"
FT                   /rpt_type=TANDEM
FT                   /citation=[3]
XX
SQ   Sequence 3952 BP; 1381 A; 806 C; 848 G; 917 T; 0 other;
     attttagaca caagcgagag gatcatggcg gatggcccca ggtgtaagcg cagaaagcag        60
     gcgaacccgc ggcgcaataa cgttacaaat tataatactg tggtagaaac aaattcagat       120
     tcagatgatg aagacaaact gcatattgtg gaagaagaaa gtgttacaga tgcagctgac       180
     tgtgaaggtg taccagagga tgacctgcca acagaccaga cagtgttacc agggaggagc       240
     agtgaaagag aagggaatgc taagaactgc tgggaggatg acagaaagga agggcaagaa       300
     atcctggggc ctgaagctca ggcagatgaa gcaggatgta cagtaaaaga tgatgaatgc       360
     gagtcagatg cagaaaatga gcaaaaccat gatcctaatg ttgaagagtt tctacaacaa       420
     caagacactg ctgtcatttt tcctgaggca cctgaagagg accagaggca gggcacacca       480
     gaagccagtg gtcatgatga aaatggaaca ccagatgcat tttcacaatt actcacctgt       540
     ccatattgtg atagaggcta taaacgcttt acctctctga aagaacacat taaatatcgt       600
     catgaaaaga atgaagataa ctttagttgc tccctgtgca gttacacctt tgcatacaga       660
     acccaacttg aacgtcacat gacatcacat aaatcaggaa gagatcaaag acatgtgacg       720
     cagtctgggt gtaatcgtaa attcaaatgc actgagtgtg gaaaagcttt caaatacaaa       780
     catcacctaa aagagcactt aagaattcac agtggagaga agccatatga atgcccaaac       840
     tgcaagaaac gcttttccca ttctggctcc tatagctcac acataagcag taagaaatgt       900
     atcagcttga tacctgtgaa tgggcgacca agaacaggac tcaagacatc tcagtgttct       960
     tcaccgtctc tttcagcatc accaggcagt cccacacgac cacagatacg gcaaaagata      1020
     gagaataaac cccttcaaga acaactttct gttaaccaaa ttaaaactga acctgtggat      1080
     tatgaattca aacccatagt ggttgcttca ggaatcaact gttcaacccc tttacaaaat      1140
     ggggttttca ctggtggtgg cccattacag gcaaccagtt ctcctcaggg catggtgcaa      1200
     gctgttgttc tgccaacagt tggtttggtg tctcccataa gtatcaattt aagtgatatt      1260
     cagaatgtac ttaaagtggc gatagatggt aatgtaataa ggcaagtgtt ggagaataat      1320
     caagccaatc ttgcatccaa agaacaagaa acaatcaatg cttcacccat acaacaaggt      1380
     ggccattctg ttatttcagc catcagtctt cctttggttg atcaagatgg aacaaccaaa      1440
     attatcatca actacagtct tgagcagcct agccaacttc aagttgttcc tcaaaattta      1500
     aaaaaagaaa atccagtcgc tacaaacagt tgtaaaagtg aaaagttacc agaagatctt      1560
     actgttaagt ctgagaagga caaaagcttt gaaggggggg tgaatgatag cacttgtctt      1620
     ctgtgtgatg attgtccagg agatattaat gcacttccag aattaaagca ctatgaccta      1680
     aagcagccta ctcagcctcc tccactccct gcagcagaag ctgagaagcc tgagtcctct      1740
     gtttcatcag ctactggaga tggcaatttg tctcctagtc agccaccttt aaagaacctc      1800
     ttgtctctcc taaaagcata ttatgctttg aatgcacaac caagtgcaga agagctctca      1860
     aaaattgctg attcagtaaa cctaccactg gatgtagtaa aaaagtggtt tgaaaagatg      1920
     caagctggac agatttcagt gcagtcttct gaaccatctt ctcctgaacc aggcaaagta      1980
     aatacccctg ccaagaacaa tgatcagcct caatctgcaa atgcaaatga accccaggac      2040
     agcacagtaa atctacaaag tcctttgaag atgactaact ccccagtttt accagtggga      2100
     tcaaccacca atggttccag aagtagtaca ccatccccat cacctctaaa cctttcctca      2160
     tccagaaata cacagggtta cttgtacaca gctgagggtg cacaagaaga gccacaagta      2220
     gaacctcttg atctttcact accaaagcaa cagggagaat tattagaaag gtcaactatc      2280
     actagtgttt accagaacag tgtttattct gtccaggaag aacccttgaa cttgtcttgc      2340
     gcaaaaaagg agccacaaaa ggacagttgt gttacagact cagaaccagt tgtaaatgta      2400
     atcccaccaa gtgccaaccc cataaatatc gctataccta cagtcactgc ccagttaccc      2460
     acaatcgtgg ccattgctga ccagaacagt gttccatgct taagagcgct agctgccaat      2520
     aagcaaacga ttctgattcc ccaggtggca tacacctact caactacggt cagccctgca      2580
     gtccaagaac cacccttgaa agtgatccag ccaaatggaa atcaggatga aagacaagat      2640
     actagctcag aaggagtatc aaatgtagag gatcagaatg actctgattc tacaccgccc      2700
     aaaaagaaaa tgcggaagac agaaaatgga atgtatgctt gtgatttgtg tgacaagata      2760
     ttccaaaaga gtagttcatt attgagacat aaatatgaac acacaggtaa aagacctcat      2820
     gagtgtggaa tctgtaaaaa ggcatttaaa cacaaacatc atttgattga acacatgcga      2880
     ttacattctg gagaaaagcc ctatcaatgt gacaaatgtg gaaagcgctt ctcacactct      2940
     gggtcttatt ctcaacacat gaatcatcgc tactcctact gtaagagaga agcggaagaa      3000
     cgtgacagca cagagcagga agaggcaggg cctgaaatcc tctcgaatga gcacgtgggt      3060
     gccagggcgt ctccctcaca gggcgactcg gacgagagag agagtttgac aagggaagag      3120
     gatgaagaca gtgaaaaaga ggaagaggag gaggataaag agatggaaga attgcaggaa      3180
     gaaaaagaat gtgaaaaacc acaaggggat gaggaagagg aggaggagga ggaagaagtg      3240
     gaagaagaag aggtagaaga ggcagagaat gagggagaag aagcaaaaac tgaaggtctg      3300
     atgaaggatg acagggctga aagtcaagca agcagcttag gacaaaaagt aggcgagagt      3360
     agtgagcaag tgtctgaaga aaagacaaat gaagcctaat cgtttttcta gaaggaaaat      3420
     aaattctaat tgataatgaa tttcgttcaa tattatcctt gcttttcatg gaaacacagt      3480
     aacctgtatg ctgtgattcc tgttcactac tgtgtaaagt aaaaactaaa aaaatacaaa      3540
     atacaaaaca cacacacaca cacacacaca cacacacaca cacacacaca caaaataaat      3600
     ccgggtgtgc ctgaacctca gacctagtaa tttttcatgc agttttcaaa gttaggaaca      3660
     agtttgtaac atgcagcaga ttagaaaacc ttaatgactc agagagcaac aatacaagag      3720
     gttaaaggaa gctgattaat tagatatgca tctggcattg ttttatctta tcagtattat      3780
     cactcttatg ttggtttatt cttaagctgt acaattggga gaaattttat aattttttat      3840
     tggtaaacat atgctaaatc cgcttcagta ttttattatg ttttttaaaa tgtgagaact      3900
     tctgcactac aaaattccct tcacagagaa gtataatgta gttccggaat tc              3952
//

If you have problems or comments...

PBIL Back to PBIL home page