(data stored in ACNUC31108 zone)

EMBL: X62654

ID   X62654; SV 1; linear; genomic DNA; STD; HUM; 4370 BP.
XX
AC   X62654; S37524;
XX
DT   24-NOV-1993 (Rel. 37, Created)
DT   14-NOV-2006 (Rel. 89, Last updated, Version 4)
XX
DE   H.sapiens gene for Me491/CD63 antigen
XX
KW   antigen; ME491/CD63 antigen.
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-4370
RA   Hotta H.;
RT   ;
RL   Submitted (17-OCT-1991) to the INSDC.
RL   H. Hotta, Kobe University School of Medicine, Dept of Microbiology, 7-5-1
RL   Kusunoki-cho Chuo-ku, Hyogo 650, JAPAN
XX
RN   [2]
RP   1-4370
RX   DOI; 10.1016/S0006-291X(05)81004-6.
RX   PUBMED; 1599482.
RA   Hotta H., Miyamoto H., Hara I., Takahashi N., Homma M.;
RT   "Genomic structure of the ME491/CD63 antigen gene and functional analysis
RT   of the 5'-flanking regulatory sequences";
RL   Biochem. Biophys. Res. Commun. 185(1):436-442(1992).
XX
DR   MD5; fb69a80ee1a0c78d09c29a6f665850cd.
DR   EPD; EP73084; HS_CD63.
DR   Ensembl-Gn; ENSG00000135404; homo_sapiens.
DR   Ensembl-Tr; ENST00000257857; homo_sapiens.
DR   Ensembl-Tr; ENST00000420846; homo_sapiens.
DR   Ensembl-Tr; ENST00000546939; homo_sapiens.
DR   Ensembl-Tr; ENST00000549117; homo_sapiens.
DR   Ensembl-Tr; ENST00000550776; homo_sapiens.
DR   Ensembl-Tr; ENST00000552692; homo_sapiens.
DR   Ensembl-Tr; ENST00000552754; homo_sapiens.
DR   EuropePMC; PMC108220; 9596698.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..4370
FT                   /organism="Homo sapiens"
FT                   /chromosome="12"
FT                   /map="q12-q13"
FT                   /mol_type="genomic DNA"
FT                   /clone_lib="LN87"
FT                   /clone="lambda2"
FT                   /cell_line="peripheral blood leukocytes"
FT                   /cell_type="peripheral blood leukocytes"
FT                   /db_xref="taxon:9606"
FT   regulatory      529..536
FT                   /note="AP-1 binding site"
FT                   /regulatory_class="enhancer"
FT   regulatory      612..621
FT                   /note="Sp1 binding site"
FT                   /regulatory_class="promoter"
FT   exon            658..715
FT                   /number=1
FT   mRNA            join(658..715,1316..1392,2328..2516,2701..2775,2870..2965,
FT                   3403..3543,3768..3851,4038..4190)
FT                   /note="ME491/CD63 antigen"
FT   intron          716..1315
FT                   /number=1
FT   exon            1316..1392
FT                   /number=2
FT   CDS_pept        join(1327..1392,2328..2516,2701..2775,2870..2965,
FT                   3403..3543,3768..3851,4038..4103)
FT                   /product="ME491 /CD63 antigen"
FT                   /db_xref="GOA:P08962"
FT                   /db_xref="HGNC:HGNC:1692"
FT                   /db_xref="InterPro:IPR000301"
FT                   /db_xref="InterPro:IPR008952"
FT                   /db_xref="InterPro:IPR018499"
FT                   /db_xref="InterPro:IPR018503"
FT                   /db_xref="InterPro:IPR042028"
FT                   /db_xref="UniProtKB/Swiss-Prot:P08962"
FT                   /protein_id="CAA44519.1"
FT                   /translation="MAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQ
FT                   GATPGSLLPVVIIAVGVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAG
FT                   YVFRDKVMSEFNNNFRQQMENYPKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKN
FT                   RVPDSCCINVTVGCGINFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIV
FT                   FACCLVKSIRSGYEVM"
FT   intron          1393..2327
FT                   /number=2
FT   exon            2328..2516
FT                   /number=3
FT   intron          2517..2700
FT                   /number=3
FT   exon            2701..2775
FT                   /number=4
FT   intron          2776..2869
FT                   /number=4
FT   exon            2870..2965
FT                   /number=5
FT   intron          2966..3402
FT                   /number=5
FT   exon            3403..3543
FT                   /number=6
FT   intron          3544..3767
FT                   /number=6
FT   exon            3768..3851
FT                   /number=7
FT   intron          3852..4037
FT                   /number=7
FT   exon            4038..4190
FT                   /number=8
FT   regulatory      4164..4170
FT                   /regulatory_class="polyA_signal_sequence"
XX
SQ   Sequence 4370 BP; 817 A; 1125 C; 1467 G; 961 T; 0 other;
     ggatccctgg aaaatggaga agctgtgcta atagaggggg gccagaaatc cccactctag        60
     aatgctgtag aatgttggga gacacccagg atgtgagcca gggactttct ggaagtgttt       120
     gttctggccc cacccgaccc caggcagtcc ccagctgtct gcacagtcgg atggggaggg       180
     ggcttgcaca gagttggagc cagaggagag agctggctca tcccctacgg taggatgggg       240
     aaacctcaca gaccacattg tcacccggcc tcagctctcc gccccggcgc tcagagggta       300
     actctcaccc acctcgtccg cttctctgaa ccagagtgac ccaggctgcc gtccgccccg       360
     ctctcctacc ccgagttggc acggaggtat agcgccagag gggggcccca ggcgccccga       420
     ggtcttgccc ttgcggcttt ccctttgcgg gggtgggcgc cttcttccgg gtaggggcca       480
     cgtggccctg gccgggcggg gggctcggcc caccccgcgc cgggcccagt gactcaggcc       540
     gcagctgtta ccgcgtcaca tgagggaggc cggcggccac tcggcggggg aggggaccgt       600
     ggctggagcc cggggcgggg ccgcgcggca ggcggggcgg gagccggggg gcgcagctag       660
     agagccccgg agccgcggcg ggagaggaac gcgcagccag ccttgggaag cccaggtgag       720
     gccgcgggga cccggcggac ttcggcgcgg gctgggagag accacccgca gtcccttcct       780
     ccagggctcg ccccaggccc gcggagactc gtccggcgct ctccagccgc cctggagcaa       840
     ctttgcttcg aagttccctg ggcccgggca gggtgtggcg ggggtgctgg ctgcactttt       900
     tttttttttg gtgggcgggg aggtcagagc ccaggggaaa ggggctgggg cgggggtcgg       960
     ggttgggctg aagaccgttt ctccaggctg ggtgttgggt ggggaaaggg tgtttgacgc      1020
     ccggagactg gcgggccgag ggtcggcgtc aggctcaagc ccctgccggc gcccttggat      1080
     ctgtcctggg ccccagaggc ggcggggcgg ggtccgggct tcgcggccgt cgcccccacc      1140
     cctctcctgc gggtaaagag ggggctggga gacgtggatc cgaccgcggg tttccgggtg      1200
     ggaggggccg ggaatcgggg ccgtgaaggg aagccctcga gggccggccg ggagcccgga      1260
     aaccgaggtc ccccttcggc cagttttaat ccccccgccc tcccctctgc cccaggcccg      1320
     gcagccatgg cggtggaagg aggaatgaaa tgtgtgaagt tcttgctcta cgtcctcctg      1380
     ctggcctttt gcgtgagtgg cgaggggtcc tggggggcgc gccggcaggg tgcggggaga      1440
     cctggctcca cagtggtgag ggctgaggga atgagaatta aggcagctgg agaccagatg      1500
     tggaaagaaa gccagggaaa gacagcgcag ccactccctc ctccagtttt cctggacacc      1560
     tgaggcttgt ttccaccgag aatggccatc ctgggtgtgc agcaacccct acccccatcc      1620
     ctcctggccc ttcctgtctg gtgacccaac cacttgtgat atggggcagt ggggcaacca      1680
     gccaaccgcc tgatgctatc gccatggggc ttcccttcgc tctcccttct cccctctctc      1740
     cctccccaac cctctcatcc ctgtccagcc cctctccccc tttccctcct cccagcgctt      1800
     gggggtgagg aagggctctg cccacttcaa tttgctcctg ccctgggctc ctggcttgag      1860
     aggctactgt ttgtataggg agggacacat cactcttgct cccttttcct cttcccttct      1920
     cctggcctaa ctggccagag gaaccttagt cacagctgat gcgcgcgtgg atgtgcactg      1980
     gaggatagtg agggggcagt tctgggcgcg aattgagctg ggagccctgg aggcctgtag      2040
     aaagcattat tctaggtcag aaatacgtgt cttgaggtca aggctttctg ggaggttttt      2100
     gaatttggtc atgtccctga ttaaagagcc gggaggggat caggggaggt aggggcaggc      2160
     aaggatgggt catcccccta ccccacagcc aaagaaattc cctagaggtg tgagaatctc      2220
     tcttggggat ggggtcaagt ctgtgtccta ggtgtacccc ctgccctcca ccatggaggg      2280
     ccactgtgtt gtggatatgg cctaatcctc acctgatttt ctcttaggcc tgtgcagtgg      2340
     gactgattgc cgtgggtgtc ggggcacagc ttgtcctgag tcagaccata atccaggggg      2400
     ctacccctgg ctctctgttg ccagtggtca tcatcgcagt gggtgtcttc ctcttcctgg      2460
     tggcttttgt gggctgctgc ggggcctgca aggagaacta ttgtcttatg atcacggtgc      2520
     gttggggcgg accaacatgg gcggtctggg actgccagag cagcttggtt cgggctcagg      2580
     aaggtgggtg aggtgggtgg gtgaggaaga cctttgtgag tgtccaggga ccggctgtgc      2640
     caaaacgggc ccctgtaatg catagactcc aaacttgact tctgtccttt gctcctgcag      2700
     tttgccatct ttctgtctct tatcatgttg gtggaggtgg ccgcagccat tgctggctat      2760
     gtgtttagag ataaggtaag cagggaataa tgggaagggc ctgcctcagc cgggtctggg      2820
     accctggtgc ttgaattctg actgcaacag tgctcctccg tactctcagg tgatgtcaga      2880
     gtttaataac aacttccggc agcagatgga gaattacccg aaaaacaacc acactgcttc      2940
     gatcctggac aggatgcagg cagatgtgag tggggttgct gggagcaggg gtggtgggaa      3000
     tagagaattc tcatctccaa ggctgggtgt ggtgactcac gcctgtaatc tcagcacttt      3060
     tgaaggccga ggtgggcaga tcacctgagg tcagaagttc aagactagcc tggccaacgt      3120
     ggtgaaaccc tgtctctact aaaaatacaa aaattagcca ggtgtggtgg tgagtgcctg      3180
     taatcccacc tactcaggag ggtgaggcag gagaatcgct tgaacccggg aggcggaggt      3240
     tgcagtgagc cgagattgag ccaccgctgg gcacttgtct gggcaacaga gcaagtctct      3300
     gtctcaaaaa aaaaaaaaaa aaaaaaaaag aattctcatc tccatattga aggtgaaggt      3360
     tcacttaaca accttcttct ccatatttct tccctccccc agtttaagtg ctgtggggct      3420
     gctaactaca cagattggga gaaaatccct tccatgtcga agaaccgagt ccccgactcc      3480
     tgctgcatta atgttactgt gggctgtggg attaatttca acgagaaggc gatccataag      3540
     gaggtaggga ggagactgtg tatgggactt gggaaacctg ggaaatgttt tagaatgcaa      3600
     gagacccagg atggaggtgg acagggtcag ggatggggag gggatctgga aatgctaagg      3660
     gtggggtgaa aggtacaggg gcagggaaga gactgatgga ccaagggagg gggttggggt      3720
     gggaagtttc tgatggtgct tttgtccttt gtgcctgcca ccttcagggc tgtgtggaga      3780
     agattggggg ctggctgagg aaaaatgtgc tggtggtagc tgcagcagcc cttggaattg      3840
     cttttgtcga ggtaagagat aaccctgagc aggggctggg actctgtcca gggtgcctgg      3900
     agggaagggg ctgaggggag gagggtgctg aacaggaggt actggcctgg gagtgtgtgt      3960
     ttggagtctc ttgcatgggt ctgaggtagc tagcccttct gactcctctc cacccctgtc      4020
     cccatcgggc cttctaggtt ttgggaattg tctttgcctg ctgcctcgtg aagagtatca      4080
     gaagtggcta cgaggtgatg taggggtctg gtctcctcag cctcctcatc tgggggagtg      4140
     gaatagtatc ctccaggttt ttcaattaaa cggattattt tttcagaccg aaaagagatg      4200
     gtctgagttt gtcttagagt gatgcttgat tccttccttt ccttactgat gttccctgtc      4260
     ctctgggacc ttaatgcatg tgtacttcga ggtctatttt ggggggtgtt tgggaaagga      4320
     ggactttgcg aaggtgttgg ttgggcaggc agtgggagaa gtgaggatcc                 4370
//

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