(data stored in SCRATCH zone)

GenBank: X68776

LOCUS       X68776                   993 bp    DNA     linear   BCT 15-MAY-1998
DEFINITION  E.coli (c-167) dhps gene for dihydropteroate synthase.
ACCESSION   X68776
VERSION     X68776.1
KEYWORDS    dihydropteroate synthase; sulfonamide resistance.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 993)
  AUTHORS   Swedberg,G., Fermer,C. and Skold,O.
  TITLE     Point mutations in the dihydropteroate synthase gene causing
            sulfonamide resistance
  JOURNAL   Adv. Exp. Med. Biol. 338, 555-558 (1993)
   PUBMED   8304179
REFERENCE   2  (bases 1 to 993)
  AUTHORS   Swedberg,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-SEP-1992) G. Swedberg, Uppsala, Dept of
            Pharmaceutical, Div of Microbiol, Biomedical Center, PO Box 581,
            751 23 Uppsala, SWEDEN
FEATURES             Location/Qualifiers
     source          1..993
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="c-167"
                     /db_xref="taxon:562"
     gene            91..939
                     /gene="dhps"
     CDS_pept        91..939
                     /gene="dhps"
                     /EC_number="2.5.1.15"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="CAA48676.1"
                     /db_xref="GOA:P0AC13"
                     /db_xref="InterPro:IPR000489"
                     /db_xref="InterPro:IPR006390"
                     /db_xref="InterPro:IPR011005"
                     /db_xref="PDB:1AJ0"
                     /db_xref="PDB:1AJ2"
                     /db_xref="PDB:1AJZ"
                     /db_xref="UniProtKB/Swiss-Prot:P0AC13"
                     /translation="MKLFAQGTSLDLSHPHVMGILNVTPDSFSDGGTHNSLIDAVKHA
                     NLMINAGATIIDVGGESTRPGAAEVSVEEELQRVIPVVEAIAQRFEVWISVDTSKPEV
                     IRESAKVGAHIINDIRSLSEPGALEAAAETGLPVCLMHMQGNPKTMQEAPKYDDVFAE
                     VNRYFIEQIARCEQAGIAKEKLLLDPGFGFGKNLSHNYSLLARLAEFHHFNLPLLVGM
                     SRKSMIGQLLNVGPSERLSGSLACAVIAAMQGAHIIRVHDVKETVEAMRVVEATLSAK
                     ENKRYE"
ORIGIN
        1 taagttcccg catcagatga ctatttgtac cgaaaacccc ggggcgtgct ccggggtttt
       61 ttcttatcaa ttcataccag ggataacatc atgaaacttt ttgcccaggg tacttcactg
      121 gaccttagcc atcctcacgt aatggggatc ctcaacgtca cgcctgattc cttttcggat
      181 ggtggcacgc ataactcgct gatagatgcg gtgaaacatg cgaatctgat gatcaacgct
      241 ggcgcgacga tcattgacgt tggtggcgag tccacgcgcc caggggcggc ggaagttagc
      301 gttgaagaag agttgcaacg tgttattcct gtggttgagg caattgctca acgcttcgaa
      361 gtctggatct cagtcgatac atccaaacca gaagtcatcc gtgagtcagc gaaagttggc
      421 gctcacatta ttaatgatat ccgctccctt tccgaacctg gcgctctgga ggcggctgca
      481 gaaaccggtt taccggtttg tctgatgcat atgcagggaa atccaaaaac catgcaggaa
      541 gctccgaagt atgacgatgt ctttgcagaa gtgaatcgct actttattga gcaaatagca
      601 cgttgcgagc aggcgggtat cgcaaaagag aaattgttgc tcgaccccgg attcggtttc
      661 ggtaaaaatc tctcccataa ctattcatta ctggcgcgcc tggctgaatt tcaccatttc
      721 aacctgccgc tgttggtggg tatgtcacga aaatcgatga ttgggcagct gctgaacgtg
      781 gggccgtccg agcgcctgag cggtagtctg gcctgtgcgg tcattgccgc aatgcaaggc
      841 gcgcacatca ttcgtgttca tgacgtcaaa gaaaccgtag aagcgatgcg ggtggtggaa
      901 gccactctgt ctgcaaagga aaacaaacgc tatgagtaat cgtaaatatt tcggtaccga
      961 tgggattcgt ggtcgtgtag gggatgcgcc gat
//

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