(data stored in ACNUC5448 zone)

HOGENOM: ACAM1_1_PE1016

ID   ACAM1_1_PE1016                       STANDARD;      PRT;   310 AA.
AC   ACAM1_1_PE1016; B0C1U1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Quinolinate synthase A; EC=2.5.1 72; (ACAM1_1.PE1016).
GN   Name=nadA; OrderedLocusNames=AM1_1068;
OS   ACARYOCHLORIS MARINA MBIC11017.
OC   Bacteria; Cyanobacteria; Acaryochloris.
OX   NCBI_TaxID=329726;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACAM1_1.PE1016.
CC       Acaryochloris marina MBIC11017, complete genome.
CC   -!- ANNOTATIONS ORIGIN:B0C1U1_ACAM1
CC   -!- FUNCTION: Catalyzes the condensation of iminoaspartate with
CC       dihydroxyacetone phosphate to form quinolinate (By similarity).
CC   -!- CATALYTIC ACTIVITY: Glycerone phosphate + iminosuccinate =
CC       pyridine-2,3-dicarboxylate + 2 H(2)O + phosphate.
CC   -!- COFACTOR: Binds 1 4Fe-4S cluster per subunit (By similarity).
CC   -!- PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate
CC       from iminoaspartate: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the quinolinate synthase A family. Type 2
CC       subfamily.
CC   -!- GENE_FAMILY: HOG000222769 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B0C1U1; -.
DR   EMBL; CP000828; ABW26107.1; -; Genomic_DNA.
DR   RefSeq; YP_001515421.1; NC_009925.1.
DR   ProteinModelPortal; B0C1U1; -.
DR   STRING; B0C1U1; -.
DR   GeneID; 5679893; -.
DR   GenomeReviews; CP000828_GR; AM1_1068.
DR   KEGG; amr:AM1_1068; -.
DR   OMA; IAHPECE; -.
DR   ProtClustDB; PRK09375; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008987; F:quinolinate synthetase A activity; IEA:HAMAP.
DR   GO; GO:0016765; F:transferase activity, transferring alkyl or aryl (other than methyl) groups; IEA:InterPro.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00568; NadA_type2; 1; -.
DR   InterPro; IPR003473; NadA.
DR   InterPro; IPR023066; Quinolinate_synth_type2.
DR   Pfam; PF02445; NadA; 1.
DR   TIGRFAMs; TIGR00550; NadA; 1.
DR   HOGENOMDNA; ACAM1_1.PE1016; -.
KW   quinolinate synthetase;
KW   4Fe-4S; Complete proteome; Cytoplasm; Iron; Iron-sulfur;
KW   Metal-binding; Pyridine nucleotide biosynthesis; Transferase.
SQ   SEQUENCE   310 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSTPHDLVGA INDLKKDLNA IVLAHYYQEP EIQDVADYLG DSLGLSRQAA DTNAEVIVFA
     GVHFMAETAK ILNPDKLVLL PDVDAGCSLA DSCPPDQFAA FKAAHPDHLV ISYINCTAEI
     KAMSDIICTS SNAVHIVNQI PADRPIIFAP DQNLGRYVMA ETGRDLVLWQ GSCIVHETFS
     ERRLIELKTK NPQAEVIAHP ECEATILRHA SFIGSTTALL KYTQTSPLDT FIVATESGIL
     HQMEKQAPGK QFIPAPPTGN CACNECPYMR LNTLEKLYVS MRDRKPEITM PADIRQAALH
     PIQRMLEMSV
//

If you have problems or comments...

PBIL Back to PBIL home page