(data stored in ACNUC30567 zone)

HOGENOM: ACAM1_1_PE1202

ID   ACAM1_1_PE1202                       STANDARD;      PRT;   1198 AA.
AC   ACAM1_1_PE1202; B0C433;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=Methionine synthase; (ACAM1_1.PE1202).
GN   Name=metH; OrderedLocusNames=AM1_1256;
OS   ACARYOCHLORIS MARINA MBIC11017.
OC   Bacteria; Cyanobacteria; Acaryochloris.
OX   NCBI_TaxID=329726;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACAM1_1.PE1202.
CC       Acaryochloris marina MBIC11017, complete genome.
CC   -!- ANNOTATIONS ORIGIN:B0C433_ACAM1
CC   -!- COFACTOR: Binds 1 zinc ion per subunit (By similarity).
CC   -!- GENE_FAMILY: HOG000251408 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B0C433; -.
DR   EMBL; CP000828; ABW26293.1; -; Genomic_DNA.
DR   RefSeq; YP_001515607.1; NC_009925.1.
DR   ProteinModelPortal; B0C433; -.
DR   STRING; B0C433; -.
DR   GeneID; 5680079; -.
DR   GenomeReviews; CP000828_GR; AM1_1256.
DR   KEGG; amr:AM1_1256; -.
DR   OMA; ADCIAMS; -.
DR   ProtClustDB; CLSK893539; -.
DR   GO; GO:0005622; C:intracellular; IEA:InterPro.
DR   GO; GO:0031419; F:cobalamin binding; IEA:UniProtKB-KW.
DR   GO; GO:0008898; F:homocysteine S-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008705; F:methionine synthase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0042558; P:pteridine-containing compound metabolic process; IEA:InterPro.
DR   InterPro; IPR006158; Cobalamin-bd.
DR   InterPro; IPR011005; Dihydropteroate_synth-like.
DR   InterPro; IPR003759; Met_synth_Cbl-bd.
DR   InterPro; IPR011822; MetH.
DR   InterPro; IPR000489; Pterin-binding.
DR   InterPro; IPR003726; S_MeTrfase.
DR   InterPro; IPR004223; VitB12-dep_Met_synth_activ_dom.
DR   Gene3D; G3DSA:3.40.50.280; B12_bd; 1.
DR   Gene3D; G3DSA:3.20.20.20; Dhdropt_synth; 1.
DR   Gene3D; G3DSA:3.10.196.10; Met_synth_B12; 2.
DR   Gene3D; G3DSA:1.10.1240.10; Met_synth_B12_bd; 1.
DR   Gene3D; G3DSA:3.20.20.330; S_methyl_trans; 1.
DR   Pfam; PF02310; B12-binding; 1.
DR   Pfam; PF02607; B12-binding_2; 1.
DR   Pfam; PF02965; Met_synt_B12; 1.
DR   Pfam; PF00809; Pterin_bind; 1.
DR   Pfam; PF02574; S-methyl_trans; 1.
DR   PIRSF; PIRSF000381; MetH; 1.
DR   SUPFAM; SSF52242; Cbl-bd; 1.
DR   SUPFAM; SSF51717; DHP_synth_like; 1.
DR   SUPFAM; SSF56507; Met_synth_B12; 1.
DR   SUPFAM; SSF47644; Met_synth_Cbl-bd; 1.
DR   SUPFAM; SSF82282; S_methyl_trans; 1.
DR   TIGRFAMs; TIGR02082; MetH; 1.
DR   PROSITE; PS50974; ADOMET_ACTIVATION; 1.
DR   PROSITE; PS51332; B12_BINDING; 1.
DR   PROSITE; PS51337; B12_BINDING_NTER; 1.
DR   PROSITE; PS50970; HCY; 1.
DR   PROSITE; PS50972; PTERIN_BINDING; 1.
DR   HOGENOMDNA; ACAM1_1.PE1202; -.
KW   methionine synthase;
KW   Cobalamin; Cobalt; Complete proteome; Metal-binding;
KW   S-adenosyl-L-methionine; Zinc.
SQ   SEQUENCE   1198 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKSVFLDRLH SPERPVIVFD GAMGTSLQMQ NLTAEDFGGP EYEGCNEYLI QTKPGAVATV
     HRNFLKAGAD VIETDTFGAT SIVLAEYDLA DQAYELNKAA AELAKQVTAE FSTPEKPRFV
     AGSMGPGTKL PTLGHIDFDT LKAAYVEQAQ GLYDGGADLL LVETCQDVLQ IKAALNAIEV
     VFAEKGARLP LMVSVTVENF GTMLVGSEIG AALTVLEPYP IDILGLNCAT GPDLMKEHIK
     YLSEQSPFIV SCIPNAGLPE NVGGQAHYLL TPMELRMALM HFIEDLGVQV IGGCCGTRPD
     HIQQLAEMSQ DLKPKAREIG SRQSLPPYAP LPFVPAAASI MTTQSYDQDN SFLIVGERLN
     ASGSKKCRET LNAEDWDGLV SLARSQVKEG AHVLDVNVDY VGRDGERDMR ELASRLVNTV
     SLPLMLDSTE WTKMEAGLKV AGGKCILNST NYEDGEERFY KVLELAKTYG AGVVVGTIDE
     DGMARTAEKK FEIAKRAYDD AINYGIPAYE IFFDPLALPA STGIEEDRNN ANATISAIWQ
     IRDELPGCHI ILGVSNVSFG LNPAARVTLN SVFLHEAMAV GMDAAIVSAS KILPLAKIEE
     EHKQVCLDLI YDRRQFDGEV CTYDPLTKLT TLFEGKTTKR DRSVDTSLPV EERLKNHIID
     GERIGLEEQL DIALKDHAPL AIINTFLLDG MKVVGELFGS GQMQLPFVLQ SAQTMKAAVA
     YLEPMMDKEE ADDSGKGTVV IATVKGDVHD IGKNLVDIIL SNNGYQVINL GIKQPVDTII
     AAYREHNADC IAMSGLLVKS TAFMKDNLET FNQEGITVPV ILGGAALTPK FVNQDCQNTY
     NGQVIYGKDA FADLHFMDKL MPAKTEGQWD NLKGFLNEQD EVPESVSTNG SQPQENAAEA
     ATAAMPVDTR RSEAVDIDIE RPTPPFWGTT ILQPEDLPFD ELFWHLDLQA LIAGQWQFRK
     PKDQSREDYD AFLDQKVYPI LNQWKQRIVA EKLLHPQAIY GYFPCLAEEN SLHIYDPKVA
     ENPGDTLPEP VTTFTFPRQK SMRRLCIADF FLPKEQGIAQ KRFDVFPMQA VTVGDIATEF
     AQKLFAGDEY TEYLYFHGLA VQTAEAIAEW THARIRRELG YGESEPDNIR DMLAQRYQGS
     RYSFGYPACP NMQDQYKQLD LLQTDRINLH MDESEQLYPE QSTTAIMVYH PVAKYFSA
//

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