(data stored in ACNUC7421 zone)

HOGENOM: ACAM1_1_PE1371

ID   ACAM1_1_PE1371                       STANDARD;      PRT;   235 AA.
AC   ACAM1_1_PE1371; B0C7S1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Phosphoribosylformylglycinamidine synthase 1; EC=6.3.5
DE   3;AltName: Full=Phosphoribosylformylglycinamidine synthase I; Short=FGAM
DE   synthase I; (ACAM1_1.PE1371).
GN   Name=purQ; OrderedLocusNames=AM1_1434;
OS   ACARYOCHLORIS MARINA MBIC11017.
OC   Bacteria; Cyanobacteria; Acaryochloris.
OX   NCBI_TaxID=329726;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACAM1_1.PE1371.
CC       Acaryochloris marina MBIC11017, complete genome.
CC   -!- ANNOTATIONS ORIGIN:PURQ_ACAM1
CC   -!- CATALYTIC ACTIVITY: ATP + N(2)-formyl-N(1)-(5-phospho-D-
CC       ribosyl)glycinamide + L-glutamine + H(2)O = ADP + phosphate + 2-
CC       (formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate.
CC   -!- PATHWAY: Purine metabolism; IMP biosynthesis via de novo pathway;
CC       5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-
CC       phospho-D-ribosyl)glycinamide: step 1/2.
CC   -!- SUBUNIT: Heterodimer of two subunits, purQ and purL (By
CC       similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Contains 1 glutamine amidotransferase type-1 domain.
CC   -!- GENE_FAMILY: HOG000238240 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B0C7S1; -.
DR   EMBL; CP000828; ABW26462.1; -; Genomic_DNA.
DR   RefSeq; YP_001515776.1; NC_009925.1.
DR   ProteinModelPortal; B0C7S1; -.
DR   STRING; B0C7S1; -.
DR   GeneID; 5680254; -.
DR   GenomeReviews; CP000828_GR; AM1_1434.
DR   KEGG; amr:AM1_1434; -.
DR   OMA; FPGTNCD; -.
DR   ProtClustDB; CLSK2316661; -.
DR   BioCyc; AMAR329726:AM1_1434-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004642; F:phosphoribosylformylglycinamidine synthase activity; IEA:EC.
DR   GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:InterPro.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_00421; PurQ; 1; -.
DR   InterPro; IPR017926; GATASE_1.
DR   InterPro; IPR011698; GATase_3.
DR   InterPro; IPR010075; PRibForGlyAmidine_synth_I.
DR   Pfam; PF07685; GATase_3; 1.
DR   PIRSF; PIRSF001586; FGAM_synth_I; 1.
DR   TIGRFAMs; TIGR01737; FGAM_synth_I; 1.
DR   PROSITE; PS51273; GATASE_TYPE_1; 1.
DR   HOGENOMDNA; ACAM1_1.PE1371; -.
KW   phosphoribosylformylglycinamidine synthase I;
KW   ATP-binding; Complete proteome; Cytoplasm; Glutamine amidotransferase;
KW   Ligase; Nucleotide-binding; Purine biosynthesis.
SQ   SEQUENCE   235 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKFGVLVFPG SNCDRDVVLV TRDLLKQPTR MVWHQETDIS DLDVVVIPGG FSYGDYLRCG
     AISRFSPAMQ ATMAHAEQGK LVLGICNGFQ VLTESGLLPG ALVRNRDLHF ICDRVPVRVE
     RTNLPWTQAY QAGQVITLPI AHGEGCYYAD PETLKQLQAN QQILFRYCQP NGEITPDSNP
     NGSVENIAGI CNRQGNVVGM MPHPERASDP TLGYTDGLLL FQGVLNSLMA QGVTA
//

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