(data stored in ACNUC7421 zone)

HOGENOM: ACAM1_1_PE1634

ID   ACAM1_1_PE1634                       STANDARD;      PRT;   250 AA.
AC   ACAM1_1_PE1634; B0CB86;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Cobalamin synthase; EC=2.-.- -; (ACAM1_1.PE1634).
GN   Name=cobS; OrderedLocusNames=AM1_1704;
OS   ACARYOCHLORIS MARINA MBIC11017.
OC   Bacteria; Cyanobacteria; Acaryochloris.
OX   NCBI_TaxID=329726;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACAM1_1.PE1634.
CC       Acaryochloris marina MBIC11017, complete genome.
CC   -!- ANNOTATIONS ORIGIN:B0CB86_ACAM1
CC   -!- FUNCTION: Joins Ado-cobinamide-GDP and alpha-ribazole to generate
CC       adenosylcobalamin (Ado-cobalamin) (By similarity).
CC   -!- CATALYTIC ACTIVITY: GDP-cobinamide + alpha-ribazole = cobalamin +
CC       GMP.
CC   -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis;
CC       adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane
CC       protein (By similarity).
CC   -!- SIMILARITY: Belongs to the CobS family.
CC   -!- GENE_FAMILY: HOG000228087 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B0CB86; -.
DR   EMBL; CP000828; ABW26725.1; -; Genomic_DNA.
DR   RefSeq; YP_001516039.1; NC_009925.1.
DR   STRING; B0CB86; -.
DR   GeneID; 5680520; -.
DR   GenomeReviews; CP000828_GR; AM1_1704.
DR   KEGG; amr:AM1_1704; -.
DR   OMA; RARIFEI; -.
DR   ProtClustDB; PRK00235; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008818; F:cobalamin 5'-phosphate synthase activity; IEA:InterPro.
DR   GO; GO:0015420; F:cobalamin-transporting ATPase activity; IEA:HAMAP.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_00719; CobS; 1; -.
DR   InterPro; IPR003805; Cbl_biosynth_CobS.
DR   Pfam; PF02654; CobS; 1.
DR   TIGRFAMs; TIGR00317; CobS; 1.
DR   HOGENOMDNA; ACAM1_1.PE1634; -.
KW   cobalamin synthase;
KW   Cell inner membrane; Cell membrane; Cobalamin biosynthesis;
KW   Complete proteome; Membrane; Transferase; Transmembrane;
KW   Transmembrane helix.
SQ   SEQUENCE   250 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKHILQQIGG AIAFYSCIPL PSSWPLEFER IARWAPWIGF LLGMGIGTLD YGLALGHMPD
     LTRSALVVAL WIGLTGGLHL DGVMDTADGL AVMEPERRLT VMSDSRTGAF GVMAGTLVLL
     LKVCALSNLS IAHLPALVTA LVWGRIAQVM AIAIFPYLKP EGNNAFHANA FQGLGDLWPS
     VIGVFAIAVC QYYGFPLAWP SVLGGILMAS SLSLGISYWF YYQFKGMTGD VYGAIVEWTE
     ALILCCLTLV
//

If you have problems or comments...

PBIL Back to PBIL home page