(data stored in ACNUC7421 zone)

HOGENOM: ACAM1_1_PE4510

ID   ACAM1_1_PE4510                       STANDARD;      PRT;   324 AA.
AC   ACAM1_1_PE4510; B0C0A5;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Protoheme IX farnesyltransferase; EC=2.5.1 -;AltName:
DE   Full=Heme B farnesyltransferase;AltName: Full=Heme O synthase;
DE   (ACAM1_1.PE4510).
GN   Name=ctaB; OrderedLocusNames=AM1_4623;
OS   ACARYOCHLORIS MARINA MBIC11017.
OC   Bacteria; Cyanobacteria; Acaryochloris.
OX   NCBI_TaxID=329726;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACAM1_1.PE4510.
CC       Acaryochloris marina MBIC11017, complete genome.
CC   -!- ANNOTATIONS ORIGIN:COXX_ACAM1
CC   -!- FUNCTION: Converts heme B (protoheme IX) to heme O by substitution
CC       of the vinyl group on carbon 2 of heme B porphyrin ring with a
CC       hydroxyethyl farnesyl side group (By similarity).
CC   -!- PATHWAY: Porphyrin metabolism; heme O biosynthesis; heme O from
CC       protoheme: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane
CC       protein (Potential).
CC   -!- MISCELLANEOUS: Carbon 2 of the heme B porphyrin ring is defined
CC       according to the Fischer nomenclature (By similarity).
CC   -!- SIMILARITY: Belongs to the UbiA prenyltransferase family.
CC       Protoheme IX farnesyltransferase subfamily.
CC   -!- GENE_FAMILY: HOG000237291 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B0C0A5; -.
DR   EMBL; CP000828; ABW29597.1; -; Genomic_DNA.
DR   RefSeq; YP_001518915.1; NC_009925.1.
DR   STRING; B0C0A5; -.
DR   GeneID; 5683425; -.
DR   GenomeReviews; CP000828_GR; AM1_4623.
DR   KEGG; amr:AM1_4623; -.
DR   OMA; SSALNHY; -.
DR   ProtClustDB; CLSK2475865; -.
DR   BioCyc; AMAR329726:AM1_4623-MON; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008495; F:protoheme IX farnesyltransferase activity; IEA:InterPro.
DR   GO; GO:0048034; P:heme O biosynthetic process; IEA:InterPro.
DR   HAMAP; MF_00154; CyoE_CtaB; 1; -.
DR   InterPro; IPR006369; Protohaem_IX_farnesylTrfase.
DR   InterPro; IPR000537; UbiA_prenyltransferase.
DR   Pfam; PF01040; UbiA; 1.
DR   TIGRFAMs; TIGR01473; CyoE_ctaB; 1.
DR   PROSITE; PS00943; UBIA; 1.
DR   HOGENOMDNA; ACAM1_1.PE4510; -.
KW   protoheme IX farnesyltransferase;
KW   Cell inner membrane; Cell membrane; Complete proteome;
KW   Heme biosynthesis; Membrane; Transferase; Transmembrane;
KW   Transmembrane helix.
SQ   SEQUENCE   324 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MQKTIWAEVP WLHPGFAQTC IDFYQLTKPR LILLFLITTA AAMWVASSGQ VGPRLFLTTL
     LAGACAAGSA NTINCIYDRD IDYIMERTRH RPLPSGRIQV WQASVFAASL ALTAFFLLAF
     GANLLSACLA MAGIAVYIGV YTYWLKRSST QNIVIGGAAG AIPPLVGWAA VTGELSWAAW
     VLFAIIFIWT PPHFWPLAMM IEEDYSKVGV PMMPVVNGMA TTANQTFIYT LLLLPVTLLL
     VYPLKVSGAL YASIAIVLWV QFIHKAWQLT QTPDDKQMAR SVFKFSILYM MLLCAGMGVD
     SLPWTQQIWH HSTHILQAWI PSIG
//

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