(data stored in ACNUC30567 zone)

HOGENOM: ACAM1_1_PE4558

ID   ACAM1_1_PE4558                       STANDARD;      PRT;   191 AA.
AC   ACAM1_1_PE4558; B0C0F3;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Non-canonical purine NTP pyrophosphatase; EC=3.6.1
DE   19;AltName: Full=Non-standard purine NTP pyrophosphatase;AltName:
DE   Full=Nucleoside-triphosphate diphosphatase;AltName:
DE   Full=Nucleoside-triphosphate pyrophosphatase; (ACAM1_1.PE4558).
GN   Name=ham1; OrderedLocusNames=AM1_4672;
OS   ACARYOCHLORIS MARINA MBIC11017.
OC   Bacteria; Cyanobacteria; Acaryochloris.
OX   NCBI_TaxID=329726;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACAM1_1.PE4558.
CC       Acaryochloris marina MBIC11017, complete genome.
CC   -!- ANNOTATIONS ORIGIN:B0C0F3_ACAM1
CC   -!- FUNCTION: Pyrophosphatase that hydrolyzes non-canonical purine
CC       nucleotides such as XTP and ITP/dITP to their respective
CC       monophosphate derivatives. Might exclude non-canonical purines
CC       from DNA precursor pool, thus preventing their incorporation into
CC       DNA and avoiding chromosomal lesions (By similarity).
CC   -!- CATALYTIC ACTIVITY: A nucleoside triphosphate + H(2)O = a
CC       nucleotide + diphosphate.
CC   -!- COFACTOR: Binds 1 divalent metal cation ion per subunit; can use
CC       either magnesium or manganese (By similarity).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the HAM1 NTPase family.
CC   -!- GENE_FAMILY: HOG000293319 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B0C0F3; -.
DR   EMBL; CP000828; ABW29645.1; -; Genomic_DNA.
DR   RefSeq; YP_001518963.1; NC_009925.1.
DR   ProteinModelPortal; B0C0F3; -.
DR   STRING; B0C0F3; -.
DR   GeneID; 5683473; -.
DR   GenomeReviews; CP000828_GR; AM1_4672.
DR   KEGG; amr:AM1_4672; -.
DR   OMA; GEAHNDA; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0047429; F:nucleoside-triphosphate diphosphatase activity; IEA:HAMAP.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0006163; P:purine nucleotide metabolic process; IEA:HAMAP.
DR   HAMAP; MF_01405; Nucleoside_triphosp; 1; -.
DR   InterPro; IPR002637; Ham1p-like.
DR   InterPro; IPR020922; Nucleoside-triphosphatase.
DR   PANTHER; PTHR11067; Ham1p_like; 1.
DR   Pfam; PF01725; Ham1p_like; 1.
DR   TIGRFAMs; TIGR00042; TIGR00042; 1.
DR   HOGENOMDNA; ACAM1_1.PE4558; -.
KW   Complete proteome; Hydrolase; Magnesium; Manganese; Metal-binding;
KW   Nucleotide metabolism; Nucleotide-binding.
SQ   SEQUENCE   191 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MPPLIVATQN PGKLKEMQQH LADLPWELQL MPPDLEIEET GTTFRENAIL KATQVAKHLG
     QWAIADDSGL EVMALDGAPG LYSARYGKTD IDRIQRLLTE LQGKTDRSAQ FVCVIALARP
     DGSVACQAKG VCPGEILQAP QGEGGFGYDP IFYVPSQQQT FAELSATAKR QISHRGEAIK
     VLMPQLLALE T
//

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