(data stored in ACNUC30567 zone)

HOGENOM: ACEAZ_1_PE1537

ID   ACEAZ_1_PE1537                       STANDARD;      PRT;   145 AA.
AC   ACEAZ_1_PE1537; D9QRE8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Deoxyuridine 5'-triphosphate nucleotidohydrolase;
DE   Short=dUTPase; EC=3.6.1 23;AltName: Full=dUTP pyrophosphatase;
DE   (ACEAZ_1.PE1537).
GN   Name=dut; OrderedLocusNames=Acear_1583;
OS   ACETOHALOBIUM ARABATICUM DSM 5501.
OC   Bacteria; Firmicutes; Clostridia; Halanaerobiales; Halobacteroidaceae;
OC   Acetohalobium.
OX   NCBI_TaxID=574087;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACEAZ_1.PE1537.
CC       Acetohalobium arabaticum DSM 5501 chromosome, complete genome.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:D9QRE8_ACEAZ
CC   -!- FUNCTION: This enzyme is involved in nucleotide metabolism: it
CC       produces dUMP, the immediate precursor of thymidine nucleotides
CC       and it decreases the intracellular concentration of dUTP so that
CC       uracil cannot be incorporated into DNA (By similarity).
CC   -!- CATALYTIC ACTIVITY: dUTP + H(2)O = dUMP + diphosphate.
CC   -!- COFACTOR: Magnesium (By similarity).
CC   -!- PATHWAY: Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP
CC       (dUTP route): step 2/2.
CC   -!- SIMILARITY: Belongs to the dUTPase family.
CC   -!- GENE_FAMILY: HOG000028966 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D9QRE8; -.
DR   EMBL; CP002105; ADL13089.1; -; Genomic_DNA.
DR   RefSeq; YP_003828154.1; NC_014378.1.
DR   GeneID; 9513640; -.
DR   GenomeReviews; CP002105_GR; Acear_1583.
DR   KEGG; aar:Acear_1583; -.
DR   GO; GO:0004170; F:dUTP diphosphatase activity; IEA:HAMAP.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:HAMAP.
DR   GO; GO:0046080; P:dUTP metabolic process; IEA:InterPro.
DR   HAMAP; MF_00116; dUTPase_bact; 1; -.
DR   InterPro; IPR008180; dUTP_pyroPase.
DR   InterPro; IPR008181; dUTP_pyroPase_sf.
DR   Pfam; PF00692; dUTPase; 1.
DR   TIGRFAMs; TIGR00576; Dut; 1.
DR   HOGENOMDNA; ACEAZ_1.PE1537; -.
KW   deoxyuridine 5'-triphosphate nucleotidohydrolase;
KW   Complete proteome; Hydrolase; Magnesium; Metal-binding;
KW   Nucleotide metabolism.
SQ   SEQUENCE   145 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MEIEIKRLDD SLPLPEYKHR GEDAGMDLYS REEGVLKPGK YGLFKTGIAI ALPRGYAGFI
     NPRSGLAVDY GVTVLNADGV IDPGYRGEIG VPLINHGAEE FKVKKKTRIA QLVVQKYEEV
     EWKEVEELST TDRGEGGFGH TGLRD
//

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