(data stored in ACNUC30567 zone)

HOGENOM: ACEP3_1_PE61

ID   ACEP3_1_PE61                         STANDARD;      PRT;   199 AA.
AC   ACEP3_1_PE61; C7JAU3;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Non-canonical purine NTP pyrophosphatase; EC=3.6.1
DE   19;AltName: Full=Non-standard purine NTP pyrophosphatase;AltName:
DE   Full=Nucleoside-triphosphate diphosphatase;AltName:
DE   Full=Nucleoside-triphosphate pyrophosphatase; (ACEP3_1.PE61).
GN   OrderedLocusNames=APA01_00620;
OS   ACETOBACTER PASTEURIANUS IFO 3283-01.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Acetobacter.
OX   NCBI_TaxID=634452;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACEP3_1.PE61.
CC       Acetobacter pasteurianus IFO 3283-01, complete genome.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:C7JAU3_ACEP3
CC   -!- FUNCTION: Pyrophosphatase that hydrolyzes non-canonical purine
CC       nucleotides such as XTP and ITP/dITP to their respective
CC       monophosphate derivatives. Might exclude non-canonical purines
CC       from DNA precursor pool, thus preventing their incorporation into
CC       DNA and avoiding chromosomal lesions (By similarity).
CC   -!- CATALYTIC ACTIVITY: A nucleoside triphosphate + H(2)O = a
CC       nucleotide + diphosphate.
CC   -!- COFACTOR: Binds 1 divalent metal cation ion per subunit; can use
CC       either magnesium or manganese (By similarity).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the HAM1 NTPase family.
CC   -!- GENE_FAMILY: HOG000293319 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C7JAU3; -.
DR   EMBL; AP011121; BAH98219.1; -; Genomic_DNA.
DR   RefSeq; YP_003186599.1; NC_013209.1.
DR   ProteinModelPortal; C7JAU3; -.
DR   STRING; C7JAU3; -.
DR   GeneID; 8434358; -.
DR   GenomeReviews; AP011121_GR; APA01_00620.
DR   KEGG; apt:APA01_00620; -.
DR   OMA; GVYTADW; -.
DR   ProtClustDB; PRK00120; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0047429; F:nucleoside-triphosphate diphosphatase activity; IEA:HAMAP.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0006163; P:purine nucleotide metabolic process; IEA:HAMAP.
DR   HAMAP; MF_01405; Nucleoside_triphosp; 1; -.
DR   InterPro; IPR002637; Ham1p-like.
DR   InterPro; IPR020922; Nucleoside-triphosphatase.
DR   PANTHER; PTHR11067; Ham1p_like; 1.
DR   Pfam; PF01725; Ham1p_like; 1.
DR   TIGRFAMs; TIGR00042; TIGR00042; 1.
DR   HOGENOMDNA; ACEP3_1.PE61; -.
KW   Complete proteome; Hydrolase; Magnesium; Manganese; Metal-binding;
KW   Nucleotide metabolism; Nucleotide-binding.
SQ   SEQUENCE   199 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MNSIKLERGS TLVLATHNAG KLAEFATLLA DFGIKVVSAG ELNLPEPEET ATTFAGNAAI
     KALAAAKAAN LPALADDSGL CVAALDGAPG IYSARWAGPN KDFAGAMARI EKEIGQGERN
     AWFICVLCLA LPDGRTESFE GRIDGQIVWP PRGTQGHGYD PIFAPEGETR TFAEMADAEK
     NAISHRARAF DTFKNACLS
//

If you have problems or comments...

PBIL Back to PBIL home page