(data stored in ACNUC30567 zone)

HOGENOM: ACHXA_1_PE3307

ID   ACHXA_1_PE3307                       STANDARD;      PRT;   207 AA.
AC   ACHXA_1_PE3307; E3HHW9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Non-canonical purine NTP pyrophosphatase; EC=3.6.1
DE   19;AltName: Full=Non-standard purine NTP pyrophosphatase;AltName:
DE   Full=Nucleoside-triphosphate diphosphatase;AltName:
DE   Full=Nucleoside-triphosphate pyrophosphatase; (ACHXA_1.PE3307).
GN   Name=rdgB; OrderedLocusNames=AXYL_03349;
OS   ACHROMOBACTER XYLOSOXIDANS A8.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Achromobacter.
OX   NCBI_TaxID=762376;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACHXA_1.PE3307.
CC       Achromobacter xylosoxidans A8 chromosome, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:E3HHW9_ACHXA
CC   -!- FUNCTION: Pyrophosphatase that hydrolyzes non-canonical purine
CC       nucleotides such as XTP and ITP/dITP to their respective
CC       monophosphate derivatives. Might exclude non-canonical purines
CC       from DNA precursor pool, thus preventing their incorporation into
CC       DNA and avoiding chromosomal lesions (By similarity).
CC   -!- CATALYTIC ACTIVITY: A nucleoside triphosphate + H(2)O = a
CC       nucleotide + diphosphate.
CC   -!- COFACTOR: Binds 1 divalent metal cation ion per subunit; can use
CC       either magnesium or manganese (By similarity).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the HAM1 NTPase family.
CC   -!- GENE_FAMILY: HOG000293319 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E3HHW9; -.
DR   EMBL; CP002287; ADP16669.1; -; Genomic_DNA.
DR   RefSeq; YP_003979384.1; NC_014640.1.
DR   GeneID; 9897681; -.
DR   GenomeReviews; CP002287_GR; AXYL_03349.
DR   KEGG; axy:AXYL_03349; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0047429; F:nucleoside-triphosphate diphosphatase activity; IEA:HAMAP.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0006163; P:purine nucleotide metabolic process; IEA:HAMAP.
DR   HAMAP; MF_01405; Nucleoside_triphosp; 1; -.
DR   InterPro; IPR002637; Ham1p-like.
DR   InterPro; IPR020922; Nucleoside-triphosphatase.
DR   PANTHER; PTHR11067; Ham1p_like; 1.
DR   Pfam; PF01725; Ham1p_like; 1.
DR   TIGRFAMs; TIGR00042; TIGR00042; 1.
DR   HOGENOMDNA; ACHXA_1.PE3307; -.
KW   nucleoside-triphosphatase;
KW   Complete proteome; Hydrolase; Magnesium; Manganese; Metal-binding;
KW   Nucleotide metabolism; Nucleotide-binding.
SQ   SEQUENCE   207 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTAPKIPDSL RRVVLASNNP GKLREFSALF APLGMELVPQ GELGVPEAEE PHVTFVENAL
     AKARHASRLT GLPALADDSG LCVAALGGAP GVYSARYAKM HGGEKSDQAN NELLVRKLAG
     VADRSAWYVA VLALVRAEND PRPLIGEGLW HGEIIDQPEG ANGFGYDPHF YLPDQALTAA
     ALDPEEKNRL SHRARALREL LSKLSQA
//

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