(data stored in ACNUC7421 zone)

HOGENOM: ACHXA_1_PE3608

ID   ACHXA_1_PE3608                       STANDARD;      PRT;   706 AA.
AC   ACHXA_1_PE3608; E3HM92;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=Enoyl-CoA hydratase/3,2-trans-enoyl-CoA
DE   isomerase/3-hydroxyacyl-CoA dehydrogenase; EC=1.1.1.35; EC=4.2.1.17;
DE   EC=5.3.3 8; (ACHXA_1.PE3608).
GN   OrderedLocusNames=AXYL_03650;
OS   ACHROMOBACTER XYLOSOXIDANS A8.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Achromobacter.
OX   NCBI_TaxID=762376;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACHXA_1.PE3608.
CC       Achromobacter xylosoxidans A8 chromosome, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:E3HM92_ACHXA
CC   -!- CATALYTIC ACTIVITY: (S)-3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA
CC       + NADH.
CC   -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC   -!- GENE_FAMILY: HOG000261347 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E3HM92; -.
DR   EMBL; CP002287; ADP16970.1; -; Genomic_DNA.
DR   RefSeq; YP_003979685.1; NC_014640.1.
DR   GeneID; 9897982; -.
DR   GenomeReviews; CP002287_GR; AXYL_03650.
DR   KEGG; axy:AXYL_03650; -.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.
DR   GO; GO:0050662; F:coenzyme binding; IEA:InterPro.
DR   GO; GO:0004165; F:dodecenoyl-CoA delta-isomerase activity; IEA:EC.
DR   GO; GO:0004300; F:enoyl-CoA hydratase activity; IEA:EC.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH_C-like.
DR   InterPro; IPR001753; Crotonase_core.
DR   InterPro; IPR013328; DH_multihelical.
DR   InterPro; IPR018376; Enoyl-CoA_hyd/isom_CS.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   Gene3D; G3DSA:1.10.1040.10; Opine_DH; 2.
DR   Pfam; PF00725; 3HCDH; 2.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   Pfam; PF00378; ECH; 1.
DR   SUPFAM; SSF48179; 6DGDH_C_like; 2.
DR   PROSITE; PS00166; ENOYL_COA_HYDRATASE; 1.
DR   HOGENOMDNA; ACHXA_1.PE3608; -.
KW   Complete proteome; Fatty acid metabolism; Isomerase; Lipid metabolism;
KW   Lyase; NAD; Oxidoreductase.
SQ   SEQUENCE   706 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDSASTGAA NTRRYDDILV VTIDHPPVNA LSAAVRADLA AAIRDAQADP QVRAILLLGA
     GKNFIAGADI REFGKPPQPP ILPEVCNQIE ASAKPVVAAL HGAALGGGLE VALAAHYRVA
     LAGARLGLPE VNLGLLPGAG GTQRAPRLMG AQAALDLMLS GKHLTAGSAR EAGLVDALSD
     EADPLDAGLA YTRQLLALGA GPRRTRDAGA LEDRVAALAQ VDAAAERVAR TTRGLYSPAK
     IVEAVRAAIE QPFEEGLRTE RALFLQCLDS PQRAGLVHAF FAERDTAKMP GQEPARPRRL
     ERIGIVGGGT MGAGIAVSAL DAGFPVTMVE QDEAALERGR GRVAQVYELL VKKGRIGADE
     RDARMARYTG STRYEALDDA DLIIEAVFED MAVKQTVFAQ LDRVAKPGAV LATNTSYLDV
     NLIAAATRGP ADVLGLHFFS PANIMKLLEV VVGDHTAPDT VATGFELARR LRKIPVRAGV
     CDGFIGNRIL AVHRQAADMM MEDGASPYEI DAAVRAFGYP MGPYQMADLA GGDIGWATRK
     RRAPTRDPAL RYVQIPDRLC ERGWFGQKTG RGFYLYPDGA RQGEQDPEVL ALIDAERARA
     GVTPHAYTQE DIQRRYLAAM INEAANVLHQ GIAQRPSDID VVFLSGYGFP RYRGGPMHYA
     DSVGLNRVLA DIRGYAQEDP AFWKPSPLLV QLAESGRNFA TLNPSA
//

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