(data stored in ACNUC14238 zone)

HOGENOM: ACIB5_2_PE3003

ID   ACIB5_2_PE3003                       STANDARD;      PRT;   216 AA.
AC   ACIB5_2_PE3003; B7I636;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Ribosomal RNA large subunit methyltransferase E; EC=2.1.1
DE   166;AltName: Full=23S rRNA Um2552 methyltransferase;AltName: Full=rRNA
DE   (ACIB5_2.PE3003) (uridine-2'-O-)-methyltransferase; .
GN   Name=rlmE; Synonyms=ftsJ, rrmJ; OrderedLocusNames=AB57_3097;
OS   ACINETOBACTER BAUMANNII AB0057.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Moraxellaceae; Acinetobacter; Acinetobacter calcoaceticus/baumannii
OC   complex.
OX   NCBI_TaxID=480119;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACIB5_2.PE3003.
CC       Acinetobacter baumannii AB0057, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:RLME_ACIB5
CC   -!- FUNCTION: Specifically methylates the uridine in position 2552 of
CC       23S rRNA at the 2'-O position of the ribose in the fully assembled
CC       50S ribosomal subunit (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + uridine(2552) in 23S
CC       rRNA = S-adenosyl-L-homocysteine + 2'-O-methyluridine(2552) in 23S
CC       rRNA.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. RlmE
CC       family.
CC   -!- GENE_FAMILY: HOG000162366 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B7I636; -.
DR   EMBL; CP001182; ACJ41682.1; -; Genomic_DNA.
DR   RefSeq; YP_002320418.1; NC_011586.1.
DR   ProteinModelPortal; B7I636; -.
DR   SMR; B7I636; 34-212.
DR   STRING; B7I636; -.
DR   GeneID; 7045139; -.
DR   GenomeReviews; CP001182_GR; AB57_3097.
DR   KEGG; abn:AB57_3097; -.
DR   OMA; WSQIAAK; -.
DR   ProtClustDB; CLSK830698; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0001510; P:RNA methylation; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   HAMAP; MF_01547; 23SrRNA_methyltr_E; 1; -.
DR   InterPro; IPR015507; rRNA-MeTfrase_E.
DR   InterPro; IPR002877; rRNA_MeTrfase_RrmJ/FtsJ.
DR   PANTHER; PTHR10920; rRNA-MeTfrase_J; 1.
DR   Pfam; PF01728; FtsJ; 1.
DR   PIRSF; PIRSF005461; 23S_rRNA_mtase; 1.
DR   HOGENOMDNA; ACIB5_2.PE3003; -.
KW   ribosomal RNA large subunit methyltransferase J;
KW   Complete proteome; Cytoplasm; Methyltransferase; rRNA processing;
KW   S-adenosyl-L-methionine; Transferase.
SQ   SEQUENCE   216 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MATRITNQKL SKSSRAWMRE HLDDPFVKKA QKEGYRARAA YKLLEIQEKY KLIKPGMTVV
     DLGAAPGSWS QIAGKLVGSK GLVIASDILP MDALPDVTFL QGDFREEAVF EKLLNILNGR
     QVDIVISDMA PNTSGNRAVD QPRQIYLCEL ALDFAQKVLG PNGQFVVKVF QGAGFDEFRK
     QVVDSFDVLK TAKPAASRAR SKEVFLVGQG RKKALQ
//

If you have problems or comments...

PBIL Back to PBIL home page