(data stored in ACNUC15324 zone)

HOGENOM: ACIBT_3_PE1487

ID   ACIBT_3_PE1487                       STANDARD;      PRT;   253 AA.
AC   ACIBT_3_PE1487; A3M4Z0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=3-deoxy-manno-octulosonate cytidylyltransferase; EC=2.7.7
DE   38;AltName: Full=CMP-2-keto-3-deoxyoctulosonic acid synthase; Short=CKS;
DE   Short=CMP-KDO synthase; (ACIBT_3.PE1487).
GN   Name=kdsB; OrderedLocusNames=A1S_1557;
OS   ACINETOBACTER BAUMANNII ATCC 17978.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Moraxellaceae; Acinetobacter; Acinetobacter calcoaceticus/baumannii
OC   complex.
OX   NCBI_TaxID=400667;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACIBT_3.PE1487.
CC       Acinetobacter baumannii ATCC 17978, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:KDSB_ACIBT
CC   -!- FUNCTION: Activates KDO (a required 8-carbon sugar) for
CC       incorporation into bacterial lipopolysaccharide in Gram-negative
CC       bacteria (By similarity).
CC   -!- CATALYTIC ACTIVITY: CTP + 3-deoxy-D-manno-octulosonate =
CC       diphosphate + CMP-3-deoxy-D-manno-octulosonate.
CC   -!- PATHWAY: Nucleotide-sugar biosynthesis; CMP-3-deoxy-D-manno-
CC       octulosonate biosynthesis; CMP-3-deoxy-D-manno-octulosonate from
CC       3-deoxy-D-manno-octulosonate and CTP: step 1/1.
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; lipopolysaccharide
CC       biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- SIMILARITY: Belongs to the kdsB family.
CC   -!- GENE_FAMILY: HOG000007602 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A3M4Z0; -.
DR   EMBL; CP000521; ABO11984.2; -; Genomic_DNA.
DR   RefSeq; YP_001084586.2; NC_009085.1.
DR   PDB; 3POL; X-ray; 2.30 A; A=1-253.
DR   PDBsum; 3POL; -.
DR   ProteinModelPortal; A3M4Z0; -.
DR   STRING; A3M4Z0; -.
DR   GeneID; 4918839; -.
DR   GenomeReviews; CP000521_GR; A1S_1557.
DR   KEGG; acb:A1S_1557; -.
DR   NMPDR; fig|400667.4.peg.1615; -.
DR   eggNOG; COG1212; -.
DR   ProtClustDB; PRK05450; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008690; F:3-deoxy-manno-octulosonate cytidylyltransferase activity; IEA:EC.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_00057; CMP-KDO_synth; 1; -.
DR   InterPro; IPR003329; Cytidylyl_trans.
DR   InterPro; IPR004528; KdsB.
DR   Pfam; PF02348; CTP_transf_3; 1.
DR   TIGRFAMs; TIGR00466; KdsB; 1.
DR   HOGENOMDNA; ACIBT_3.PE1487; -.
KW   3-deoxy-manno-octulosonate cytidylyltransferase;
KW   3D-structure; Complete proteome; Cytoplasm;
KW   Lipopolysaccharide biosynthesis; Nucleotidyltransferase; Transferase.
SQ   SEQUENCE   253 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKHIVIPARF SSSRLPGKPL LLIHDRPMIL RVVDQAKKVE GFDDLCVATD DERIAEICRA
     EGVDVVLTSA DHPSGTDRLS EVARIKGWDA DDIIVNVQGD EPLLPAQLVQ QVAKLLVDKP
     NCSMSTLCEP IHALDEFQRD SIVKVVMSKQ NEALYFSRAT IPYDRDGAKR DEPTLHTQAF
     RHLGLYAYRV SLLQEYVTWE MGKLEKLESL EQLRVLENGH RIAIAVAEAN LPPGVDTQAD
     LDRLNNMPVE SFE
//

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