(data stored in SCRATCH3701 zone)

HOGENOM6: ACIC1_1_PE6

ID   ACIC1_1_PE6                          STANDARD;      PRT;   834 AA.
AC   ACIC1_1_PE6; A0LQS2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (ACIC1_1.PE6).
GN   OrderedLocusNames=Acel_0006;
OS   ACIDOTHERMUS CELLULOLYTICUS 11B.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Frankineae;
OC   Acidothermaceae; Acidothermus.
OX   NCBI_TaxID=351607;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACIC1_1.PE6.
CC       Acidothermus cellulolyticus 11B, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:A0LQS2_ACIC1
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A0LQS2; -.
DR   EMBL; CP000481; ABK51782.1; -; Genomic_DNA.
DR   RefSeq; YP_871768.1; NC_008578.1.
DR   ProteinModelPortal; A0LQS2; -.
DR   STRING; A0LQS2; -.
DR   GeneID; 4484715; -.
DR   GenomeReviews; CP000481_GR; Acel_0006.
DR   KEGG; ace:Acel_0006; -.
DR   eggNOG; COG0188; -.
DR   OMA; QRENVIV; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; ACIC1_1.PE6; -.
DR   PRODOM; ACIC1_1_PE6.
DR   SWISS-2DPAGE; ACIC1_1_PE6.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   834 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTQDTTLPPE GGRIEPVDLQ VEMQRSYLDY AMSVIVGRAL PDVRDGLKPV HRRVLYAMYD
     GGYRPDRGYV KCARVVGDVI GSYHPHGDAA VYDTLVRLAQ PWVMRHPLVD GQGNFGSPGN
     DPAAAMRYTE CRLTPLAMEM LRDIGKETVD FVPNYDGRQM EPVILPARFP NLLVNGSAGI
     AVGMATNIPP HNLREVAAGA QWALEHPDAT REELLAALLE RIKGPDFPTG GVIVGHAGIE
     EAYRTGRGSI VMRAVVEVEE DARGRQSLVV TQLPYQVNPD NLAVRIAELV SEGRIPGIAD
     IRDDSSSRTG QRLVISLKRD AVPKVVLANL YKHTQLQDTF GANMVALVDN VPRTLSLDAF
     IRHWVAHQID VIVRRTRYDL REAERRAHIL RGLVKALDQL DAVIALIRGS ASADEARSGL
     MELLDVDEVQ ATAILDMQLR KLAALERQAI IDDLAKHEAE IADLNDILAN ESRQRAIVSE
     ELKEIVDKYG DERRTAIVPA DGDVSIEDLI AEEDVVVTIT RGGYAKRTKT SLYRSQRRGG
     KGIQGAQLRQ DDVVEHFFVT TTHHWLLFFT DKGRVYRLKA YEIPEAARSA RGQHVANLLA
     FQPDEKIAQV LALRDYDAAP YLVLATRSGL VKKTALREFD SNRTGGIIAI NLRDDDVVIG
     ARLVSPDDEL LLVSRKAQAI RFRADDEALR PMGRATSGVI GMRFHDDDAL LAMMVVRPQA
     YVFVATTKGY AKRTPIEEYP LQGRGGYGVI TAKITAERGD LVGALMVDEE DEVLAITVLG
     GVIRTRVSEV RPTSRATMGV RLMDLAENDA LVAITRNAER GGDAGIGEEE SPAR
//

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