(data stored in SCRATCH3701 zone)

HOGENOM6: ACIF2_1_PE857

ID   ACIF2_1_PE857                        STANDARD;      PRT;   845 AA.
AC   ACIF2_1_PE857; B7J6V0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (ACIF2_1.PE857).
GN   Name=gyrA; OrderedLocusNames=AFE_0894;
OS   ACIDITHIOBACILLUS FERROOXIDANS ATCC 23270.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Acidithiobacillales;
OC   Acidithiobacillaceae; Acidithiobacillus.
OX   NCBI_TaxID=243159;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACIF2_1.PE857.
CC       Acidithiobacillus ferrooxidans ATCC 23270, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:B7J6V0_ACIF2
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B7J6V0; -.
DR   EMBL; CP001219; ACK78946.1; -; Genomic_DNA.
DR   RefSeq; YP_002425372.1; NC_011761.1.
DR   STRING; B7J6V0; -.
DR   GeneID; 7137036; -.
DR   GenomeReviews; CP001219_GR; AFE_0894.
DR   KEGG; afr:AFE_0894; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; ACIF2_1.PE857; -.
DR   PRODOM; ACIF2_1_PE857.
DR   SWISS-2DPAGE; ACIF2_1_PE857.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   845 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MIEFAKETIP VSLEKEMRQS YLDYAMSVIV GRALPDARDG LKPVHRRVLF AMHEMSNDWN
     KPYKKSARVV GDVIGKYHPH GDTAVYDTMV RMAQDFSMRY PLIDGQGNFG SVDGDSPAAM
     RYTEVRMSRI AHEMLADLEK ETVDFGPNYD EKEMEPLVMP ARIPNLLING SAGIAVGMAT
     NIPPHNLTEV ISACLALVDD PETPDEDLFT LVPAPDFPTA GFIHGRAGSI EAYRTGRGRV
     VMRARCEFET DKKSNRQSII VTELPYQVNK AKLIERIAEM VKEKRLEGIS DLRDESDKSG
     MRIAIELKRD ANADVVLNNL YQHTVMQSVF NINMVALLDG APRTLGLRDL LQAFIQHRRE
     VVTRRTVFEL KKARDRAHIL EGLAVALVNL DPLISLIRAA ASPAEAKAQM LAKSWEPGMV
     AALLVERGEP SEGMHADGYH LSELQAQAIL DLRLHRLTGL EQDKIRDEYL ALLDRIRELL
     EILGSKTRLM EVIREELVAI RDQYGDARRS EIVADTGDIS TEDLITEEEM VVTFTHAGYI
     KAQPVTVFNA QRRGGKGKMA TTTKEEDFVE RMFCASTHAY CLFFSNLGKV FWQKVYQLPQ
     AGRGAKGKPI VNMLSLAPTE RITAVLPVRD FTEGQFVCMV TSLGVVKKTP VMEYSRPRSQ
     GINAINLDPG DRLVAVGLSD GQREFMLFTR HGMAVRFPEA KVRAMGRNAR GVRGISLEEN
     DRVISAQWVD SSQVILTTTA NGYGKLTKVD EYRRTNRGGK GVIAIQTNER NGDVVGALAV
     TERDELMLVS DHGTLIRIAV NSIRRTGRNA QGVRLINLGE GEQLAGLALI ADTDEEEGEQ
     TDLPQ
//

If you have problems or comments...

PBIL Back to PBIL home page