(data stored in SCRATCH zone)

HOGENOM: ACIF5_1_PE1008

ID   ACIF5_1_PE1008                       STANDARD;      PRT;   240 AA.
AC   ACIF5_1_PE1008; B5EQ25;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Orotidine 5'-phosphate decarboxylase; EC=4.1.1 23;AltName:
DE   Full=OMP decarboxylase; (ACIF5_1.PE1008).
GN   Name=pyrF; OrderedLocusNames=Lferr_1028;
OS   ACIDITHIOBACILLUS FERROOXIDANS ATCC 53993.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Acidithiobacillales;
OC   Acidithiobacillaceae; Acidithiobacillus.
OX   NCBI_TaxID=380394;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACIF5_1.PE1008.
CC       Acidithiobacillus ferrooxidans ATCC 53993 chromosome, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:B5EQ25_ACIF5
CC   -!- FUNCTION: Catalyzes the decarboxylation of orotidine 5'-
CC       monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By
CC       similarity).
CC   -!- CATALYTIC ACTIVITY: Orotidine 5'-phosphate = UMP + CO(2).
CC   -!- PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo
CC       pathway; UMP from orotate: step 2/2.
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the OMP decarboxylase family.
CC   -!- SIMILARITY: Belongs to the OMP decarboxylase family. Type 1
CC       subfamily.
CC   -!- GENE_FAMILY: HOG000226070 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B5EQ25; -.
DR   EMBL; CP001132; ACH83270.1; -; Genomic_DNA.
DR   RefSeq; YP_002219477.1; NC_011206.1.
DR   STRING; B5EQ25; -.
DR   GeneID; 6876997; -.
DR   GenomeReviews; CP001132_GR; Lferr_1028.
DR   KEGG; afe:Lferr_1028; -.
DR   OMA; TVHAYPQ; -.
DR   ProtClustDB; CLSK2407750; -.
DR   GO; GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
DR   GO; GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.
DR   GO; GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
DR   HAMAP; MF_01200_B; OMPdecase_type1_B; 1; -.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR014732; OMPdecase.
DR   InterPro; IPR018089; OMPdecase_AS.
DR   InterPro; IPR001754; OMPdeCOase_dom.
DR   InterPro; IPR011060; RibuloseP-bd_barrel.
DR   Gene3D; G3DSA:3.20.20.70; Aldolase_TIM; 1.
DR   Pfam; PF00215; OMPdecase; 1.
DR   SMART; SM00934; OMPdecase; 1.
DR   SUPFAM; SSF51366; RibP_bind_barrel; 1.
DR   TIGRFAMs; TIGR01740; PyrF; 1.
DR   PROSITE; PS00156; OMPDECASE; 1.
DR   HOGENOMDNA; ACIF5_1.PE1008; -.
KW   orotidine 5'-phosphate decarboxylase;
KW   Complete proteome; Decarboxylase; Lyase; Pyrimidine biosynthesis.
SQ   SEQUENCE   240 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MISPLIIALD YADERDALIL ADQLDPAQCR VKVGKELFTA SGPSIVERLQ ERGFDVFLDL
     KFHDIPQTVA KACRAASRLG VWMLNVHASG GSAMLRAARE AVEDGGGTRR PLLIAVTVLT
     SMDDDALHEV GVNSSVVEQV GRLATLAAAC ALDGLVCSAL EADRLRNVLP ELLRVTPGIR
     PAQYAEDDQR RIMTPAAALA AGSDFLVVGR PVTAAVDPAR ALGQILNELV AKPGDSREPG
//

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