(data stored in SCRATCH3701 zone)

HOGENOM6: ACIFD_1_PE6

ID   ACIFD_1_PE6                          STANDARD;      PRT;   816 AA.
AC   ACIFD_1_PE6; C7M119;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (ACIFD_1.PE6).
GN   OrderedLocusNames=Afer_0006;
OS   ACIDIMICROBIUM FERROOXIDANS DSM 10331.
OC   Bacteria; Actinobacteria; Acidimicrobidae; Acidimicrobiales;
OC   Acidimicrobineae; Acidimicrobiaceae; Acidimicrobium.
OX   NCBI_TaxID=525909;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACIFD_1.PE6.
CC       Acidimicrobium ferrooxidans DSM 10331, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:C7M119_ACIFD
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C7M119; -.
DR   EMBL; CP001631; ACU52981.1; -; Genomic_DNA.
DR   RefSeq; YP_003108654.1; NC_013124.1.
DR   STRING; C7M119; -.
DR   GeneID; 8322052; -.
DR   GenomeReviews; CP001631_GR; Afer_0006.
DR   KEGG; afo:Afer_0006; -.
DR   OMA; QRENVIV; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; ACIFD_1.PE6; -.
DR   PRODOM; ACIFD_1_PE6.
DR   SWISS-2DPAGE; ACIFD_1_PE6.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   816 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MPDEPTPDAS NVELIELQEE MERSFLEYSL SVIIARALPD ARDGLKPVHR RILYSMYDAG
     YRPDRPHVKC AKVVGDVMSR FHPHGDAAIY DALVRMAQDF SLLHPLIDGH GNFGSPDPST
     GPAASRYTEC RLAPIALELL AGIDEDTVDF VPNYDSQTVE PSVLPARFPN LLVNGSQGIA
     VGMATQIPSH NLGEVVDAIA YLIDHPEATV DELMRFVPGP DFPTGGIILG RDGIRDAYRT
     GRGSVKLRAV ATIEEARSGY QIVVTEIPFQ TSVEVIADKI RHLVEEKLLE GIRDMKNFSA
     GSETRFVIEL KRDANPNVVL NNLYRLTPLQ TSFPIQMLAL VDGAPRTLNL LGLCQIYVDH
     QREVIRRRSE FRLGKARERL HIVEGLLSCI DQLDAVIATI RASEDRAAAR AALMAEPFGF
     SELQANHILD MTLGRLTRLG REELEEEAAT LRATIAELEA ILADAQRLSA VVKDEMLAAT
     AEYRQARRTR FEVDPGDFAA EDLIEDEPIV VLISRSGYIK AVPESSFKAQ GRGGRGVVGA
     RVKDEDEIAH VISSSMLSRL LVFSSRGRVY QLRGYELPKL ERSARGTALV NLVPLADDER
     ITSVMGTKDF PEDADLVFFT RNGMVKRTAM AEYARSRRDG IIAIDVRGDD ELVSVVVATE
     EHDGVVFTKR GQVLRFPLAE VRRTGRATAG VRSIRRADGD WIVAGGLIED GVEVLLVTSR
     GYGKRTPLDS FPVHHRGGAG IRGIGLTERK GELVAAAFVR PEDEVLIVSS QGQMIRVRIG
     DISNQGRYAT GVKLISLQAE ESVASVGVVP ESGTDA
//

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