(data stored in ACNUC30567 zone)

HOGENOM: ACIFV_1_PE1758

ID   ACIFV_1_PE1758                       STANDARD;      PRT;   379 AA.
AC   ACIFV_1_PE1758; P11570; D2RM66;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=(R)-2-hydroxyglutaryl-CoA dehydratase subunit beta;
DE   EC=4.2.1 -; (ACIFV_1.PE1758).
GN   Name=hgdB; OrderedLocusNames=Acfer_1814;
OS   ACIDAMINOCOCCUS FERMENTANS DSM 20731.
OC   Bacteria; Firmicutes; Negativicutes; Selenomonadales; Acidaminococcaceae;
OC   Acidaminococcus.
OX   NCBI_TaxID=591001;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACIFV_1.PE1758.
CC       Acidaminococcus fermentans DSM 20731, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:HGDB_ACIFV
CC   -!- FUNCTION: Catalyzes the reversible dehydration of 2-
CC       hydroxyglutaryl-CoA to glutaconyl-CoA. This is a key step in the
CC       fermentation of glutamate.
CC   -!- COFACTOR: Binds 1 4Fe-4S cluster.
CC   -!- COFACTOR: FMN.
CC   -!- COFACTOR: Riboflavin.
CC   -!- COFACTOR: Magnesium.
CC   -!- ENZYME REGULATION: Activated by the hgdC protein.
CC   -!- PATHWAY: Amino-acid degradation; L-glutamate degradation via
CC       hydroxyglutarate pathway; crotonoyl-CoA from L-glutamate: step
CC       4/5.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta subunit.
CC   -!- GENE_FAMILY: HOG000058635 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; P11570; D2RM66; -.
DR   EMBL; X14252; CAA32466.1; -; Genomic_DNA.
DR   EMBL; CP001859; ADB48168.1; -; Genomic_DNA.
DR   PIR; S04478; DWDXBF.
DR   RefSeq; YP_003399483.1; NC_013740.1.
DR   GeneID; 8738317; -.
DR   GenomeReviews; CP001859_GR; Acfer_1814.
DR   KEGG; afn:Acfer_1814; -.
DR   ProtClustDB; CLSK900138; -.
DR   BioCyc; MetaCyc:MONOMER-1044; -.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR010327; HGD-D.
DR   Pfam; PF06050; HGD-D; 1.
DR   HOGENOMDNA; ACIFV_1.PE1758; -.
KW   4Fe-4S; Complete proteome; Direct protein sequencing; FMN; Iron;
KW   Iron-sulfur; Lyase; Magnesium; Metal-binding.
SQ   SEQUENCE   379 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAISALIEEF QKVSASPKTM LAKYKAQGKK AIGCLPYYVP EELVYAAGMV PMGVWGCNGK
     QEVRSKEYCA SFYCTIAQQS LEMLLDGTLD GLDGIITPVL CDTLRPMSQN FKVAMKDKMP
     VIFLAHPQVR QNAAGKQFTY DAYSEVKGHL EEICGHEITN DAILDAIKVY NKSRAARREF
     CKLANEHPDL IPASVRATVL RAAYFMLKDE YTEKLEELNK ELAAAPAGKF DGHKVVVSGI
     IYNMPGILKA MDDNKLAIAA DDCAYESRSF AVDAPEDLDN GLQALAVQFS KQKNDVLLYD
     PEFAKNTRSE HVCNLVKESG AEGLIVFMMQ FCDPEEMEYP DLKKALDAHH IPHVKIGVDQ
     MTRDFGQAQT ALEAFAESL
//

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