(data stored in ACNUC7421 zone)

HOGENOM: ACIS3_1_PE1009

ID   ACIS3_1_PE1009                       STANDARD;      PRT;   735 AA.
AC   ACIS3_1_PE1009; D9Q280;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=K(+)-insensitive pyrophosphate-energized proton pump;
DE   EC=3.6.1 1;AltName: Full=Membrane-bound proton-translocating
DE   pyrophosphatase;AltName: Full=Pyrophosphate-energized inorganic
DE   pyrophosphatase; (ACIS3_1.PE1009).
GN   Name=hppA; OrderedLocusNames=ASAC_1013;
OS   ACIDILOBUS SACCHAROVORANS 345-15.
OC   Archaea; Crenarchaeota; Thermoprotei; Acidilobales; Acidilobaceae;
OC   Acidilobus.
OX   NCBI_TaxID=666510;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACIS3_1.PE1009.
CC       Acidilobus saccharovorans 345-15 chromosome, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:D9Q280_ACIS3
CC   -!- FUNCTION: Proton pump that utilizes the energy of pyrophosphate
CC       hydrolysis as the driving force for proton movement across the
CC       membrane. Generates a proton motive force (By similarity).
CC   -!- CATALYTIC ACTIVITY: Diphosphate + H(2)O = 2 phosphate.
CC   -!- COFACTOR: Magnesium (By similarity).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein
CC       (By similarity).
CC   -!- SIMILARITY: Belongs to the H(+)-translocating pyrophosphatase (TC
CC       3.A.10) family. K(+)-insensitive subfamily.
CC   -!- GENE_FAMILY: HOG000007098 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D9Q280; -.
DR   EMBL; CP001742; ADL19418.1; -; Genomic_DNA.
DR   RefSeq; YP_003816449.1; NC_014374.1.
DR   GeneID; 9499255; -.
DR   GenomeReviews; CP001742_GR; ASAC_1013.
DR   KEGG; asc:ASAC_1013; -.
DR   OMA; KVMNTIS; -.
DR   GO; GO:0005887; C:integral to plasma membrane; IEA:HAMAP.
DR   GO; GO:0009678; F:hydrogen-translocating pyrophosphatase activity; IEA:HAMAP.
DR   GO; GO:0004427; F:inorganic diphosphatase activity; IEA:HAMAP.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:HAMAP.
DR   GO; GO:0015992; P:proton transport; IEA:UniProtKB-KW.
DR   HAMAP; MF_01129; PPase_energized_pump; 1; -.
DR   InterPro; IPR004131; PPase-energised_H-pump.
DR   Pfam; PF03030; H_PPase; 1.
DR   PIRSF; PIRSF001265; H+-PPase; 1.
DR   TIGRFAMs; TIGR01104; V_PPase; 1.
DR   HOGENOMDNA; ACIS3_1.PE1009; -.
KW   Proton-translocating pyrophosphatase;
KW   Cell membrane; Complete proteome; Hydrogen ion transport; Hydrolase;
KW   Ion transport; Magnesium; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
SQ   SEQUENCE   735 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKIDLLIASV SAVVGFVSIV IAIWLARWVL SQDPGPENIK FISDAIASGA KAYLFRQYRT
     LSIVLVALAI IIGIGISAVN HSYTLGGSSA AAFIVGALGS MAAGYIGMYV TTRSASRAAM
     AARNSAFASL RVAWRAGAVM GLSLAGIALF LISALYMGFT SIIPSSWALA LVSMAFGASL
     VTLFMRVGGG IYTKAADLGA DLVGKVEKGI PEDDPRNPGV IADNVGDNVG DVAGMAADVF
     ESYIVIVTGA IFLSWIMGWS ATYPQLVVLP LLYGALALIA TFVGISILRL KGSQHPLTAI
     SIDIYETIAI SIALFFIVSV ALLGNLGLKV ALVAPLAASL GAVVAPLVLA LTGYYTHYTY
     KPVKDIANQA LISPATVIVT GYAYGLISAI PVILLIAFVL GLTYALGYFA FSSLVSSSVL
     SGYSGFLAGI YGTALASVGL LSVAGIIITA DSFGPVSDNA AGVAEMASLP EEVRDRLDVL
     DAVGNTTKAT TKGYAISSAA MAALVLFIGF IFEVISVAGK YVADPVDLLN GISVINPNVL
     IGALIGAVVV YVLASRTLGA VGKTAMEIVE EIRRQFRERP GIMEWKEKPD YARVVDIATR
     RALQEFMMPV LVAIIAPVAA GLLLGWQAIA GLIMGAILVG VPRALLMANA GGAWDNAKKY
     IEAGLDPKLG GKGSDAHKAA VVGDTVGDPF KDTTGPSMNP LIKVLNTLSV VFAPMIVAAN
     ASLGVWMLVH GLLAL
//

If you have problems or comments...

PBIL Back to PBIL home page