(data stored in ACNUC14238 zone)

HOGENOM: ACISD_1_PE760

ID   ACISD_1_PE760                        STANDARD;      PRT;   216 AA.
AC   ACISD_1_PE760; D8JDM6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Ribosomal RNA large subunit methyltransferase E; EC=2.1.1
DE   166;AltName: Full=23S rRNA Um2552 methyltransferase;AltName: Full=rRNA
DE   (ACISD_1.PE760) (uridine-2'-O-)-methyltransferase; .
GN   Name=rlmE; Synonyms=ftsJ, rrmJ; OrderedLocusNames=AOLE_03830;
OS   ACINETOBACTER SP. DR1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Moraxellaceae; Acinetobacter.
OX   NCBI_TaxID=436717;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACISD_1.PE760.
CC       Acinetobacter sp. DR1 chromosome, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:D8JDM6_ACISD
CC   -!- FUNCTION: Specifically methylates the uridine in position 2552 of
CC       23S rRNA at the 2'-O position of the ribose in the fully assembled
CC       50S ribosomal subunit (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + uridine(2552) in 23S
CC       rRNA = S-adenosyl-L-homocysteine + 2'-O-methyluridine(2552) in 23S
CC       rRNA.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. RlmE
CC       family.
CC   -!- GENE_FAMILY: HOG000162366 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D8JDM6; -.
DR   EMBL; CP002080; ADI89663.1; -; Genomic_DNA.
DR   RefSeq; YP_003731036.1; NC_014259.1.
DR   GeneID; 9381182; -.
DR   GenomeReviews; CP002080_GR; AOLE_03830.
DR   KEGG; acd:AOLE_03830; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008650; F:rRNA (uridine-2'-O-)-methyltransferase activity; IEA:HAMAP.
DR   HAMAP; MF_01547; 23SrRNA_methyltr_E; 1; -.
DR   InterPro; IPR015507; rRNA-MeTfrase_E.
DR   InterPro; IPR002877; rRNA_MeTrfase_RrmJ/FtsJ.
DR   PANTHER; PTHR10920; rRNA-MeTfrase_J; 1.
DR   Pfam; PF01728; FtsJ; 1.
DR   PIRSF; PIRSF005461; 23S_rRNA_mtase; 1.
DR   HOGENOMDNA; ACISD_1.PE760; -.
KW   FtsJ-like methyltransferase family protein;
KW   Complete proteome; Cytoplasm; Methyltransferase; rRNA processing;
KW   S-adenosyl-L-methionine; Transferase.
SQ   SEQUENCE   216 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MATRITNQKL SKSSRAWMRE HLDDPFVKKA QKEGYRARAA YKLLEIQEKY KLIKPGMTVV
     DLGAAPGSWS QIAGKLVGSK GLVIASDILP MDALPDVSFL QGDFREEDVF EKLLNILNGR
     QVDIVISDMA PNTSGNRAVD QPRQIYLCEL ALDFAQKVLG PNGQLVVKVF QGAGFDEFRK
     QVVDSFDVLK TVKPAASRAR SKEVFLVGQG RKKALQ
//

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