(data stored in SCRATCH3701 zone)

HOGENOM6: ACTP2_1_PE286

ID   ACTP2_1_PE286                        STANDARD;      PRT;   896 AA.
AC   ACTP2_1_PE286; A3MZ08;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (ACTP2_1.PE286).
GN   Name=gyrA; OrderedLocusNames=APL_0286;
OS   ACTINOBACILLUS PLEUROPNEUMONIAE SEROVAR 5B STR. L20.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Actinobacillus.
OX   NCBI_TaxID=416269;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ACTP2_1.PE286.
CC       Actinobacillus pleuropneumoniae L20, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:A3MZ08_ACTP2
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A3MZ08; -.
DR   EMBL; CP000569; ABN73394.1; -; Genomic_DNA.
DR   RefSeq; YP_001052999.1; NC_009053.1.
DR   ProteinModelPortal; A3MZ08; -.
DR   SMR; A3MZ08; 30-521, 535-873.
DR   STRING; A3MZ08; -.
DR   GeneID; 4848939; -.
DR   GenomeReviews; CP000569_GR; APL_0286.
DR   KEGG; apl:APL_0286; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   PhylomeDB; A3MZ08; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; ACTP2_1.PE286; -.
DR   PRODOM; ACTP2_1_PE286.
DR   SWISS-2DPAGE; ACTP2_1_PE286.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   896 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSELAKDITP VSIEDELKTS YLDYAMSVIV GRALPDVRDG LKPVHRRVLF SMDQNSNTFN
     RPHVKSARVV GDVIGKYHPH GDSAVYDTIV RMAQPFSLRY MLVDGQGNFG SIDGDAPAAM
     RYTEVRMQKI TQELLTDLDK ETVDYSPNYD GKEMIPDVLP TKIPALLVNG SSGIAVGMAT
     NIPPHNLNEV LDGCLAYIEN EQIGIEELMR FIPGPDFPTG AIINGRKGIE EAYRTGRGKV
     YVRAKASVET TEKGREQIVV TELPYQVNKA KLIEKIAELV KDKKIEGISG IQDHSDKKGI
     SIVIEVKRDA VGEVVLNHLY SLTQMQVTFG INMVALDHGQ PKVLNLKQII EAFVKHRREV
     VTRRTIFELR KARERAHILE GLAIALANID PVIELIRNSK TADEAREGLL ARAWALGNVA
     PMLEAAGVDA SRPEDLPENL GVRDGQYYLS EAQARAILEL RLHRLTGLEH EKIVDEYKAL
     LTEIGELLRI LSSAERLMEV IREELEKVKA EFGDERRTEI TAASGDINME DLIAQEDVVV
     TLSHAGYVKY QPLSDYEAQR RGGKGKSATK MKEDDFIEKL LVANTHDTIL CFSSRGRLYQ
     LKVYQLPQAS RGARGTPIVN ILPLVKEENE RITAILPIPN GEFSADKFIF MATASGVVKK
     VSLDAFSNVR SSGLIALKLR EGDELIGVDI TDGESEIMLF SAQGRVVRFA EKAVRAMGRT
     ATGVRGIKLA TTDISSEEIE EAEIVEIENE EADESSVSLD TDRVVSLVIP RTEGDILTVT
     QNGFGKRTVI GEYPVKSRAT KGVVSIKVNE RNGKVVAAVQ VEEADQIMLI TDAGTLVRTR
     VAEVSLVGRN TQGVRIIRTA DDESVVSVER VCEPDDEDEN SEALDNVEST ETSTEA
//

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