(data stored in ACNUC5340 zone)

HOGENOM: AEDAE_1158_PE13

ID   AEDAE_1158_PE13                      STANDARD;      PRT;   321 AA.
AC   AEDAE_1158_PE13; P18153; O96364; Q0IF92;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=37 kDa salivary gland allergen Aed a 2;AltName:
DE   Full=Protein D7;AltName: Allergen=Aed a 2;Flags: Precursor;
DE   (AEDAE_1158.PE13).
GN   Name=D7; ORFNames=AAEL006424;
OS   AEDES AEGYPTI.
OC   Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera;
OC   Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Culicinae;
OC   Culicini; Aedes.
OX   NCBI_TaxID=7159;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS AEDAE_1158.PE13.
CC       Aedes aegypti supercontig supercont1.204 AaegL1  sequence 1..1827752
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:ALL2_AEDAE
CC   -!- FUNCTION: Thought to be involved in blood-feeding.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=A;
CC         IsoId=P18153-1; Sequence=Displayed;
CC       Name=B;
CC         IsoId=P18153-2; Sequence=VSP_034863, VSP_034864, VSP_034865;
CC   -!- TISSUE SPECIFICITY: Expressed in the distal-lateral and medial
CC       lobes of the adult female salivary gland.
CC   -!- ALLERGEN: Causes an allergic reaction in human.
CC   -!- GENE_FAMILY: HOG000033906 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Aedes_aegypti;AAEL006424;AAEL006424-RA;AAEL006424-PA.
DR   EMBL; AF027814; - ;
DR   EMBL; CH477389; - ;
DR   EMBL; EF173376; - ;
DR   EMBL; M33156; - ;
DR   EMBL; M33157; - ;
DR   UniProtKB/Swiss-Prot; P18153; O96364; Q0IF92; -.
DR   EMBL; M33156; AAA29347.1; -; Genomic_DNA.
DR   EMBL; M33157; AAA29348.1; -; mRNA.
DR   EMBL; EF173376; ABM68616.1; -; Genomic_DNA.
DR   EMBL; CH477389; EAT41994.1; -; Genomic_DNA.
DR   EMBL; AF027814; AAD01849.1; -; mRNA.
DR   RefSeq; XP_001657779.1; XM_001657729.1.
DR   UniGene; Aae.21977; -.
DR   UniGene; Aae.5737; -.
DR   PDB; 3DXL; X-ray; 1.30 A; A=20-321.
DR   PDB; 3DY9; X-ray; 1.70 A; A=20-321.
DR   PDB; 3DYE; X-ray; 1.75 A; A=20-321.
DR   PDB; 3DZT; X-ray; 1.80 A; A=20-321.
DR   PDBsum; 3DXL; -.
DR   PDBsum; 3DY9; -.
DR   PDBsum; 3DYE; -.
DR   PDBsum; 3DZT; -.
DR   ProteinModelPortal; P18153; -.
DR   Allergome; 3540; Aed a 2.0101.
DR   Allergome; 4; Aed a 2.
DR   EnsemblMetazoa; AAEL006424-RA; AAEL006424-PA; AAEL006424.
DR   GeneID; 5567958; -.
DR   KEGG; aag:AaeL_AAEL006424; -.
DR   GeneTree; EMGT00050000012178; -.
DR   InParanoid; P18153; -.
DR   OMA; TRCMEDN; -.
DR   OrthoDB; EOG431ZFP; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005549; F:odorant binding; IEA:InterPro.
DR   InterPro; IPR006625; Insect_phero_odorant-bd.
DR   InterPro; IPR006170; PBP_GOBP.
DR   InterPro; IPR023316; PBP_GOBP_dom.
DR   Gene3D; G3DSA:1.10.238.20; PBP_GOBP; 2.
DR   Pfam; PF01395; PBP_GOBP; 2.
DR   SMART; SM00708; PhBP; 2.
DR   SUPFAM; SSF47565; PBP_GOBP; 1.
DR   HOGENOMDNA; AEDAE_1158.PE13; -.
KW   AAEL0064243; AAEL006424-PA ; P18153; AF027814; CH477389; EF173376;
KW   M33157;
KW   3D-structure; Allergen; Alternative splicing; Secreted; Signal.
SQ   SEQUENCE   321 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKLPLLLAIV TTFSVVASTG PFDPEEMLFT FTRCMEDNLE DGPNRLPMLA KWKEWINEPV
     DSPATQCFGK CVLVRTGLYD PVAQKFDASV IQEQFKAYPS LGEKSKVEAY ANAVQQLPST
     NNDCAAVFKA YDPVHKAHKD TSKNLFHGNK ELTKGLYEKL GKDIRQKKQS YFEFCENKYY
     PAGSDKRQQL CKIRQYTVLD DALFKEHTDC VMKGIRYITK NNELDAEEVK RDFMQVNKDT
     KALEKVLNDC KSKEPSNAGE KSWHYYKCLV ESSVKDDFKE AFDYREVRSQ IYAFNLPKKQ
     VYSKPAVQSQ VMEIDGKQCP Q
//

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