(data stored in ACNUC9306 zone)

HOGENOM: AEDAE_2090_PE1

ID   AEDAE_2090_PE1                       STANDARD;      PRT;   583 AA.
AC   AEDAE_2090_PE1; Q170J7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Moesin/ezrin/radixin homolog 1; (AEDAE_2090.PE1).
GN   Name=Moe; ORFNames=AAEL007915;
OS   AEDES AEGYPTI.
OC   Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera;
OC   Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Culicinae;
OC   Culicini; Aedes.
OX   NCBI_TaxID=7159;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS AEDAE_2090.PE1.
CC       Aedes aegypti supercontig supercont1.288 AaegL1  sequence 1..1557290
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:MOEH_AEDAE
CC   -!- FUNCTION: Involved in connections of major cytoskeletal structures
CC       to the plasma membrane (By similarity).
CC   -!- SUBUNIT: Interacts with cytoskeletal actin (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell junction, adherens junction (By
CC       similarity). Cell membrane; Peripheral membrane protein;
CC       Cytoplasmic side (By similarity). Cytoplasm, cytoskeleton (By
CC       similarity).
CC   -!- SIMILARITY: Contains 1 FERM domain.
CC   -!- GENE_FAMILY: HOG000007113 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Aedes_aegypti;AAEL007915;AAEL007915-RA;AAEL007915-PA.
DR   EMBL; CH477473; - ;
DR   UniProtKB/Swiss-Prot; Q170J7; -.
DR   EMBL; CH477473; EAT40344.1; -; Genomic_DNA.
DR   RefSeq; XP_001652975.1; XM_001652925.1.
DR   UniGene; Aae.18514; -.
DR   ProteinModelPortal; Q170J7; -.
DR   SMR; Q170J7; 11-583.
DR   STRING; Q170J7; -.
DR   EnsemblMetazoa; AAEL007915-RA; AAEL007915-PA; AAEL007915.
DR   GeneID; 5569750; -.
DR   KEGG; aag:AaeL_AAEL007915; -.
DR   VectorBase; AAEL007915; Aedes aegypti.
DR   eggNOG; inNOG09212; -.
DR   GeneTree; EMGT00050000000862; -.
DR   OMA; METANDK; -.
DR   OrthoDB; EOG49KD5K; -.
DR   PhylomeDB; Q170J7; -.
DR   GO; GO:0005912; C:adherens junction; ISS:UniProtKB.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0019898; C:extrinsic to membrane; IEA:InterPro.
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; ISS:UniProtKB.
DR   InterPro; IPR019749; Band_41_domain.
DR   InterPro; IPR019750; Band_41_fam.
DR   InterPro; IPR011174; ERM.
DR   InterPro; IPR011259; ERM_C.
DR   InterPro; IPR000798; Ez/rad/moesin.
DR   InterPro; IPR014352; FERM/acyl-CoA-bd_prot_3-hlx.
DR   InterPro; IPR019748; FERM_central.
DR   InterPro; IPR019747; FERM_CS.
DR   InterPro; IPR000299; FERM_domain.
DR   InterPro; IPR018979; FERM_N.
DR   InterPro; IPR018980; FERM_PH-like_C.
DR   InterPro; IPR008954; Moesin.
DR   InterPro; IPR011993; PH_type.
DR   Gene3D; G3DSA:1.20.80.10; ACBP; 1.
DR   Gene3D; G3DSA:2.30.29.30; PH_type; 1.
DR   Pfam; PF00769; ERM; 1.
DR   Pfam; PF09380; FERM_C; 1.
DR   Pfam; PF00373; FERM_M; 1.
DR   Pfam; PF09379; FERM_N; 1.
DR   PIRSF; PIRSF002305; ERM; 1.
DR   PRINTS; PR00935; BAND41.
DR   PRINTS; PR00661; ERMFAMILY.
DR   SMART; SM00295; B41; 1.
DR   SUPFAM; SSF47031; FERM_3-hlx; 1.
DR   SUPFAM; SSF48678; Moesin; 1.
DR   PROSITE; PS00660; FERM_1; 1.
DR   PROSITE; PS00661; FERM_2; 1.
DR   PROSITE; PS50057; FERM_3; 1.
DR   HOGENOMDNA; AEDAE_2090.PE1; -.
KW   AAEL0079153; AAEL007915-PA ; Q170J7; CH477473;
KW   Actin-binding; Cell junction; Cell membrane; Cytoplasm; Cytoskeleton;
KW   Membrane.
SQ   SEQUENCE   583 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MGRPRTARVF MNVRVTTMDA ELEFAIQQST TGKQLFDQVV KTIGLREVWF FGLQYTDSKG
     DLTWIKLYKK VMSQDVQKGD PLQFKFRAKF YPEDVAEELI QDITLRLFYL QVKNAILSDE
     IYCPPETSVL LASYAVQARH GDYNKTTHVP GFLVNDRLLP QRVIDQHKMS KDEWENSITT
     WWQEHRGMLR EDAMMEYLKI AQDLEMYGVN YFEIRNKKGT ELWLGVDALG LNIYEKDDRL
     TPKIGFPWSE IRNISFNDRK FIIKPIDKKA PDFVFFAPRV RINKRILALC MGNHELYMRR
     RKPDTIDVQQ MKAQAREEKN AKQQEREKLQ LALAARERAE KKQQEYEDRL RTMQEEMERS
     QANLIEAQEM IRRLEDQLKQ LQFAKDELEA RQNELQVMIK RLEESKNMEV AERQKLEDEI
     RAKQEEVQKI QEEVSVKDTE TKRLQEEVEE ARRKQNEAAA ALLAATTTPN HHHVDEEEED
     NEEELTNGAE NGTSRDYSKD FDTDEHIKDP VEERRTLAER NERLHDQLKA LKQDLALSRD
     DTMETANDKI HRENVRQGRD KYKTLREIRK GNTKRRVDQF ENM
//

If you have problems or comments...

PBIL Back to PBIL home page