(data stored in ACNUC5448 zone)

HOGENOM: AEDAE_213_PE28

ID   AEDAE_213_PE28                       STANDARD;      PRT;   1210 AA.
AC   AEDAE_213_PE28; Q17CT3;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=Phospholipase c gamma; (AEDAE_213.PE28).
GN   ORFNames=AAEL004431, AaeL_AAEL004431;
OS   AEDES AEGYPTI.
OC   Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera;
OC   Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Culicinae;
OC   Culicini; Aedes.
OX   NCBI_TaxID=7159;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS AEDAE_213.PE28.
CC       Aedes aegypti supercontig supercont1.119 AaegL1  sequence 1..2438940
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:Q17CT3_AEDAE
CC   -!- SIMILARITY: Contains 1 C2 domain.
CC   -!- SIMILARITY: Contains 1 PI-PLC X-box domain.
CC   -!- SIMILARITY: Contains 1 PI-PLC Y-box domain.
CC   -!- SIMILARITY: Contains 1 SH3 domain.
CC   -!- GENE_FAMILY: HOG000230864 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Aedes_aegypti;AAEL004431;AAEL004431-RA;AAEL004431-PA.
DR   EMBL; CH477304; - ;
DR   UniProtKB/Swiss-Prot; Q17CT3; -.
DR   EMBL; CH477304; EAT44189.1; -; Genomic_DNA.
DR   RefSeq; XP_001649138.1; XM_001649088.1.
DR   UniGene; Aae.7652; -.
DR   ProteinModelPortal; Q17CT3; -.
DR   SMR; Q17CT3; 787-842.
DR   STRING; Q17CT3; -.
DR   EnsemblMetazoa; AAEL004431-RA; AAEL004431-PA; AAEL004431.
DR   GeneID; 5564766; -.
DR   KEGG; aag:AaeL_AAEL004431; -.
DR   VectorBase; AAEL004431; Aedes aegypti.
DR   eggNOG; inNOG09034; -.
DR   GeneTree; EMGT00050000003934; -.
DR   OMA; YRSLMYS; -.
DR   OrthoDB; EOG4V9S5F; -.
DR   PhylomeDB; Q17CT3; -.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:InterPro.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0009395; P:phospholipid catabolic process; IEA:InterPro.
DR   InterPro; IPR000008; C2_Ca-dep.
DR   InterPro; IPR008973; C2_Ca/lipid-bd_dom_CaLB.
DR   InterPro; IPR018029; C2_membr_targeting.
DR   InterPro; IPR011992; EF-hand-like_dom.
DR   InterPro; IPR011993; PH_type.
DR   InterPro; IPR015359; Phospholipase_C_EF-hand-like.
DR   InterPro; IPR001711; Phospholipase_C_Pinositol-sp_Y.
DR   InterPro; IPR001192; Pinositol_Phospholipase-C.
DR   InterPro; IPR016279; PLC-gamma.
DR   InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR   InterPro; IPR001849; Pleckstrin_homology.
DR   InterPro; IPR000909; PLipase_C_PInositol-sp_X_dom.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR001452; SH3_domain.
DR   Gene3D; G3DSA:1.10.238.10; EF-Hand_type; 2.
DR   Gene3D; G3DSA:2.30.29.30; PH_type; 3.
DR   Gene3D; G3DSA:3.20.20.190; PLC-like_Pdiesterase_TIM-brl; 2.
DR   Gene3D; G3DSA:3.30.505.10; SH2; 2.
DR   Pfam; PF00168; C2; 1.
DR   Pfam; PF09279; efhand_like; 1.
DR   Pfam; PF00388; PI-PLC-X; 1.
DR   Pfam; PF00387; PI-PLC-Y; 1.
DR   Pfam; PF00017; SH2; 2.
DR   Pfam; PF00018; SH3_1; 1.
DR   PIRSF; PIRSF000952; PLC-gamma; 1.
DR   PRINTS; PR00390; PHPHLIPASEC.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   SMART; SM00239; C2; 1.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00148; PLCXc; 1.
DR   SMART; SM00149; PLCYc; 1.
DR   SMART; SM00252; SH2; 2.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF49562; C2_CaLB; 1.
DR   SUPFAM; SSF51695; PLC-like_Pdiesterase_TIM-brl; 1.
DR   SUPFAM; SSF50044; SH3; 1.
DR   PROSITE; PS50004; C2; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50007; PIPLC_X_DOMAIN; 1.
DR   PROSITE; PS50008; PIPLC_Y_DOMAIN; 1.
DR   PROSITE; PS50001; SH2; 2.
DR   PROSITE; PS50002; SH3; 1.
DR   HOGENOMDNA; AEDAE_213.PE28; -.
KW   AAEL0044313; AAEL004431-PA ; Q17CT3; CH477304;
KW   Complete proteome; Reference proteome; SH3 domain; Transducer.
SQ   SEQUENCE   1210 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSFSSSVSLP GLGEMEQIIC SLERGTLIQK FYPRRKPEKK TLMLRRETRQ ITWSSPSQNS
     RANFEDFLEL REVKEVRLGK SSKDFEKWPE ETKKIELRKC FVVFYGSEFK LRSLSVVALS
     EKECDMWIKG LKYMVADTIN APYWLQVERW LRKEFYAMEN PRETVTLKEV KSFLPKVNCK
     ITTAKLNETF HEVDCRRRNE LGFDDFTRLY QKLMTSPNTD YFEGSMPCSN GQTVTLKEFQ
     KFLLKVQNDP LGNDEKATSN FIREYVQDPI RDVQEPYLKI QEFIDFLFSR QNEVWNSDCD
     QVYQDMNRPL AHYWISSSHN TYLTGDQFSS ESSVEAYARA LRMGCRCIEL DCWDGPDNMP
     LIFHGHTFTT KIKFKDVIKT IKEHAFVTSE YPVILSIEQN CSLTQQRKMA YAMQEVFGDM
     LLTQQVEKNE LQLPTPYQLR RKIILKHKKL PENGGKFEDG AVPNDGALVR ADETELDIRN
     TVKNGILFLE DPVDKVWNPH FFVLTQNKLF YTDSQKTERE DVRDDEFESS FSRPKESVTN
     DELHFGENWF HGKLSGGREE AENLLRQYAH LGDGTFLVRE SVTFVGDYCL SFWRQGKPNH
     CRIKLKQDKG VTKYYLMENN LFDSLYSLII YYRQNPLRSS EFYITLKEPV PQPNKHESKE
     WYHQNTTREQ SEIILHQIQT DGAFLVRPSD KGPNAFVISF RAHKKIKHCR IKVEGRLYGV
     GGMDFESLID LVNFYMKHPL YKKVKLTHPI PKDMLKRINT MNVRDFYCEE IGPKIYEIIK
     PLVLQVTVKA LYDYKARRED ELSFCKHAII TNVKKSNEQW WTGDYGGKKQ HYFPANYVQE
     ISTSDGNSDD SGSDCLMLGS LQKGSLDVHG AVVDLTYGPM PELERVLRIQ NPSMQNVFEV
     GVQTQAQAIE WMCAIKEAAQ NASALEDERK KMERNSRVAK EMSDMIIYCR SVPFKNSGWV
     FYEMSSFPET KAEKYFLQQE TKLFVRYHRN QISRVYPKGQ RLDSSNYNPV PLWNTGSQMI
     ALNYQTPDKN MQLNQAKFRD NGACGYILKP DFMFRDEFDP NDPNTLIGVE EKVIEIRIIG
     ARHLCKGGRN ITSPLVEIDL IGASFDSGIK HRTRAVADNG FNPIWDEICE FRVINPYFAL
     LRFEVQDEDM FGEPNFIGQA IFPVNALRTG YRSVPLRNKY SEELELATLL VHIRIRTQEQ
     NGSERLSLLS
//

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