(data stored in ACNUC5340 zone)

HOGENOM: AEDAE_2680_PE6

ID   AEDAE_2680_PE6                       STANDARD;      PRT;   272 AA.
AC   AEDAE_2680_PE6; Q16Y34; Q16Y33;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Alpha-tubulin N-acetyltransferase; Short=Alpha-TAT;
DE   Short=TAT; EC=2.3.1 108;AltName: Full=Acetyltransferase MEC-17;
DE   (AEDAE_2680.PE6).
GN   ORFNames=AAEL008679;
OS   AEDES AEGYPTI.
OC   Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera;
OC   Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Culicinae;
OC   Culicini; Aedes.
OX   NCBI_TaxID=7159;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS AEDAE_2680.PE6.
CC       Aedes aegypti supercontig supercont1.341 AaegL1  sequence 1..1236773
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:ATAT_AEDAE
CC   -!- FUNCTION: Specifically acetylates 'Lys-40' in alpha-tubulin on the
CC       lumenal side of microtubules. May affect microtubule stability and
CC       regulate microtubule dynamics. May be involved in neuron
CC       development (By similarity).
CC   -!- CATALYTIC ACTIVITY: Acetyl-CoA + [alpha-tubulin]-L-lysine = CoA +
CC       [alpha-tubulin]-N(6)-acetyl-L-lysine.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=B;
CC         IsoId=Q16Y34-1; Sequence=Displayed;
CC       Name=A;
CC         IsoId=Q16Y34-2; Sequence=VSP_040230, VSP_040231;
CC   -!- SIMILARITY: Belongs to the acetyltransferase ATAT1 family.
CC   -!- GENE_FAMILY: HOG000257795 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Aedes_aegypti;AAEL008679;AAEL008679-RB;AAEL008679-PB.
DR   EMBL; CH477526; - ;
DR   UniProtKB/Swiss-Prot; Q16Y34; Q16Y33; -.
DR   EMBL; CH477526; EAT39526.1; -; Genomic_DNA.
DR   EMBL; CH477526; EAT39527.1; -; Genomic_DNA.
DR   EMBL; CH477526; EAT39525.1; -; Genomic_DNA.
DR   RefSeq; XP_001653412.1; XM_001653362.1.
DR   RefSeq; XP_001653413.1; XM_001653363.1.
DR   RefSeq; XP_001653414.1; XM_001653364.1.
DR   UniGene; Aae.23504; -.
DR   EnsemblMetazoa; AAEL008679-RB; AAEL008679-PB; AAEL008679.
DR   GeneID; 5570947; -.
DR   KEGG; aag:AaeL_AAEL008679; -.
DR   VectorBase; AAEL008679; Aedes aegypti.
DR   GeneTree; EMGT00050000002048; -.
DR   OMA; FMLQHKN; -.
DR   PhylomeDB; Q16Y34; -.
DR   GO; GO:0019799; F:tubulin N-acetyltransferase activity; IEA:EC.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR007965; Touch_recpt_neuron_Mec-17.
DR   Gene3D; G3DSA:3.40.630.30; Acyl_CoA_acyltransferase; 1.
DR   PANTHER; PTHR12327; DUF738; 1.
DR   Pfam; PF05301; Mec-17; 1.
DR   HOGENOMDNA; AEDAE_2680.PE6; -.
KW   AAEL0086793; AAEL008679-PB ; Q16Y34; CH477526;
KW   Alternative splicing; Transferase.
SQ   SEQUENCE   272 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MEFRFNCHPL FRQRIVRINN SLLPTGFVAQ HRREALDATA QISEIINFVG QLSAQAQGLS
     NPVTTSQKLR NSDHHIYLMF ESNQKHGLVV GILKVGRKSL YVFDQNGETV NVTAPCVLDF
     YVHESRQRGG LGRELFDHML KEENIHPEEM AIDRPSEKLL GFLQKHYGLY KKIPQMNNFV
     VYEGFFANKH HASDIDGRRM HITASPNTNL FGPTFTTVGE QRRSSSQTRQ QVVSPPVVQQ
     PPVGRYAAKR PSCSMAQIIH NSPTTVSTEP NR
//

If you have problems or comments...

PBIL Back to PBIL home page