(data stored in ACNUC5448 zone)

HOGENOM: AEDAE_269_PE13

ID   AEDAE_269_PE13                       STANDARD;      PRT;   540 AA.
AC   AEDAE_269_PE13; Q17CE8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=Tyrosine-protein kinase src64b; (AEDAE_269.PE13).
GN   ORFNames=AAEL004592, AaeL_AAEL004592;
OS   AEDES AEGYPTI.
OC   Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera;
OC   Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Culicinae;
OC   Culicini; Aedes.
OX   NCBI_TaxID=7159;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS AEDAE_269.PE13.
CC       Aedes aegypti supercontig supercont1.124 AaegL1  sequence 1..2397010
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:Q17CE8_AEDAE
CC   -!- CATALYTIC ACTIVITY: ATP + a [protein]-L-tyrosine = ADP + a
CC       [protein]-L-tyrosine phosphate.
CC   -!- SIMILARITY: Contains 1 SH2 domain.
CC   -!- SIMILARITY: Contains 1 SH3 domain.
CC   -!- SIMILARITY: Contains 1 protein kinase domain.
CC   -!- GENE_FAMILY: HOG000233858 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Aedes_aegypti;AAEL004592;AAEL004592-RA;AAEL004592-PA.
DR   EMBL; CH477309; - ;
DR   UniProtKB/Swiss-Prot; Q17CE8; -.
DR   EMBL; CH477309; EAT44003.1; -; Genomic_DNA.
DR   RefSeq; XP_001649447.1; XM_001649397.1.
DR   UniGene; Aae.12428; -.
DR   ProteinModelPortal; Q17CE8; -.
DR   EnsemblMetazoa; AAEL004592-RA; AAEL004592-PA; AAEL004592.
DR   GeneID; 5565105; -.
DR   KEGG; aag:AaeL_AAEL004592; -.
DR   VectorBase; AAEL004592; Aedes aegypti.
DR   eggNOG; inNOG05936; -.
DR   GeneTree; EMGT00050000002730; -.
DR   OMA; NALGLCH; -.
DR   OrthoDB; EOG46T1GK; -.
DR   PhylomeDB; Q17CE8; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR011009; Kinase-like_dom.
DR   InterPro; IPR000719; Prot_kinase_cat_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR001245; Ser-Thr/Tyr_kinase.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR001452; SH3_domain.
DR   InterPro; IPR008266; Tyr_kinase_AS.
DR   InterPro; IPR020635; Tyr_kinase_cat_dom.
DR   InterPro; IPR020703; Tyr_kinase_non-rcpt_Src64B.
DR   Gene3D; G3DSA:3.30.505.10; SH2; 1.
DR   PANTHER; PTHR24418:SF147; PTHR24418:SF147; 1.
DR   Pfam; PF07714; Pkinase_Tyr; 1.
DR   Pfam; PF00017; SH2; 1.
DR   Pfam; PF00018; SH3_1; 1.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   PRINTS; PR00109; TYRKINASE.
DR   SMART; SM00252; SH2; 1.
DR   SMART; SM00326; SH3; 1.
DR   SMART; SM00219; TyrKc; 1.
DR   SUPFAM; SSF56112; Kinase_like; 1.
DR   SUPFAM; SSF50044; SH3; 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
DR   PROSITE; PS50001; SH2; 1.
DR   PROSITE; PS50002; SH3; 1.
DR   HOGENOMDNA; AEDAE_269.PE13; -.
KW   AAEL0045923; AAEL004592-PA ; Q17CE8; CH477309;
KW   ATP-binding; Complete proteome; Kinase; Nucleotide-binding;
KW   Reference proteome; SH3 domain; Transferase; Tyrosine-protein kinase.
SQ   SEQUENCE   540 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MGNKCCSKRQ DQELALSYPG GYKKGENSFT SNMSGPKHSN GGGGSLDSRY TPDPNRGQLI
     KGIPKGGVDI IRPRTTPLHP GLSTRRIVVA LYNYNAREET DVSFVKGDRM EVLDDTESDW
     WRVVHLKTRQ EGLIPWNFVA EDRSVNSEDW FFENVSRKEA DKLLLAAENP RGTFLVRPSE
     HNPNGFSLSV KDWEESRGYH VKHYKIKPLD NGGYYIATNQ TFPSLPALVL AYSKNALGLC
     HVLSSPCPKP QPQVWDLGPE LRDKWEINRN EIQLIRKLGH GNFGEVYYGK WRNNIEVAVK
     TLREGTMSTQ AFLQEAAIMK KFRHSRLVAL YAVCSKEEPI YIVQEYMSKG SLLDYLRTGD
     GQFLQFEDLI YIAAQVASGM EYLELKQLIH RDLAARNVLI GENNVAKICD FGLARVIADD
     EYCPKQGSRF PVKWTAPEAI VYGKFSIKSD VWSYGILLME LFTYGQVPYP GMHSREVIEQ
     IERGYRMPKP TNHTLPDDIY SLMLKCWDAI PEKRPTFEFL NHYFQNFTVT SEVPYREVQD
//

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