(data stored in ACNUC30567 zone)

HOGENOM: AEDAE_4703_PE7

ID   AEDAE_4703_PE7                       STANDARD;      PRT;   278 AA.
AC   AEDAE_4703_PE7; Q16HW7; Q16HW8; Q16HW9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Glucosamine-6-phosphate isomerase; EC=3.5.99 6;AltName:
DE   Full=Glucosamine-6-phosphate deaminase; Short=GNPDA; Short=GlcN6P
DE   deaminase; (AEDAE_4703.PE7).
GN   Name=Gnpda1; ORFNames=AAEL013877;
OS   AEDES AEGYPTI.
OC   Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera;
OC   Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Culicinae;
OC   Culicini; Aedes.
OX   NCBI_TaxID=7159;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS AEDAE_4703.PE7.
CC       Aedes aegypti supercontig supercont1.949 AaegL1 full sequence 1..346927
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:GNPI_AEDAE
CC   -!- CATALYTIC ACTIVITY: D-glucosamine 6-phosphate + H(2)O = D-fructose
CC       6-phosphate + NH(3).
CC   -!- SUBUNIT: Homohexamer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=3;
CC       Name=E; Synonyms=F, G;
CC         IsoId=Q16HW7-1; Sequence=Displayed;
CC         Note=No experimental confirmation available;
CC       Name=B; Synonyms=C, D;
CC         IsoId=Q16HW7-2; Sequence=VSP_032747;
CC         Note=No experimental confirmation available;
CC       Name=A;
CC         IsoId=Q16HW7-3; Sequence=VSP_032746;
CC         Note=No experimental confirmation available;
CC   -!- SIMILARITY: Belongs to the glucosamine/galactosamine-6-phosphate
CC       isomerase family.
CC   -!- GENE_FAMILY: HOG000064979 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Aedes_aegypti;AAEL013877;AAEL013877-RF;AAEL013877-PF.
DR   EMBL; CH478133; - ;
DR   UniProtKB/Swiss-Prot; Q16HW7; Q16HW8; Q16HW9; -.
DR   EMBL; CH478133; EAT33845.1; -; Genomic_DNA.
DR   EMBL; CH478133; EAT33846.1; -; Genomic_DNA.
DR   EMBL; CH478133; EAT33847.1; -; Genomic_DNA.
DR   EMBL; CH478133; EAT33848.1; -; Genomic_DNA.
DR   EMBL; CH478133; EAT33849.1; -; Genomic_DNA.
DR   EMBL; CH478133; EAT33850.1; -; Genomic_DNA.
DR   EMBL; CH478133; EAT33851.1; -; Genomic_DNA.
DR   RefSeq; XP_001657190.1; XM_001657140.1.
DR   RefSeq; XP_001657191.1; XM_001657141.1.
DR   RefSeq; XP_001657192.1; XM_001657142.1.
DR   RefSeq; XP_001657193.1; XM_001657143.1.
DR   RefSeq; XP_001657194.1; XM_001657144.1.
DR   RefSeq; XP_001657195.1; XM_001657145.1.
DR   RefSeq; XP_001657196.1; XM_001657146.1.
DR   UniGene; Aae.14907; -.
DR   ProteinModelPortal; Q16HW7; -.
DR   SMR; Q16HW7; 1-267.
DR   STRING; Q16HW7; -.
DR   EnsemblMetazoa; AAEL013877-RE; AAEL013877-PE; AAEL013877.
DR   EnsemblMetazoa; AAEL013877-RF; AAEL013877-PF; AAEL013877.
DR   EnsemblMetazoa; AAEL013877-RG; AAEL013877-PG; AAEL013877.
DR   GeneID; 5578837; -.
DR   KEGG; aag:AaeL_AAEL013877; -.
DR   VectorBase; AAEL013877; Aedes aegypti.
DR   eggNOG; inNOG06888; -.
DR   GeneTree; EMGT00050000011484; -.
DR   OMA; HSFMYNN; -.
DR   OrthoDB; EOG43XSK9; -.
DR   PhylomeDB; Q16HW7; -.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0004342; F:glucosamine-6-phosphate deaminase activity; ISS:UniProtKB.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; ISS:UniProtKB.
DR   GO; GO:0006043; P:glucosamine catabolic process; ISS:UniProtKB.
DR   GO; GO:0006044; P:N-acetylglucosamine metabolic process; IEA:InterPro.
DR   InterPro; IPR006148; Glc/Gal-6P_isomerase.
DR   InterPro; IPR004547; Glucosamine6P_isomerase.
DR   InterPro; IPR018321; Glucosamine6P_isomerase_CS.
DR   PANTHER; PTHR11280; NagB; 1.
DR   Pfam; PF01182; Glucosamine_iso; 1.
DR   TIGRFAMs; TIGR00502; NagB; 1.
DR   PROSITE; PS01161; GLC_GALNAC_ISOMERASE; 1.
DR   HOGENOMDNA; AEDAE_4703.PE7; -.
KW   AAEL0138773; AAEL013877-PF ; Q16HW7; CH478133;
KW   Alternative splicing; Carbohydrate metabolism; Cytoplasm; Hydrolase.
SQ   SEQUENCE   278 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MRLIILDTSD YVGEWSAKYV MKRINDFKPG PSRFFTLGLP TGSTPLGLYR NLIKFHQEGK
     ISFKYVKTFN MDEYVDLPRD HPESYHYFMW HNFFKHIDID PVNVHILDGN APDLVAECNA
     FEDKIKAAGG IELFIGGIGP DGHIAFNEPG SSLVSRTRVK TLAQDTLEAN ARFFGNDISK
     VPKQALTVGV GTVMDAREVM ILIIGAHKAF ALYKAIEEGV NHMWTVSAFQ QHPHTIMICD
     EDATLELRVK TVKYFKALSN VHHKLIEEGS TDVRKLCK
//

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