(data stored in ACNUC7421 zone)

HOGENOM: AEPER1_1_PE1015

ID   AEPER1_1_PE1015                      STANDARD;      PRT;   578 AA.
AC   AEPER1_1_PE1015; Q9YBQ2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Acylamino-acid-releasing enzyme; Short=AARE; EC=3.4.19
DE   1;AltName: Full=Acyl-peptide hydrolase; Short=APH;AltName:
DE   Full=Acylaminoacyl-peptidase; (AEPER1_1.PE1015).
GN   OrderedLocusNames=APE_1547.1;
OS   AEROPYRUM PERNIX K1.
OC   Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales;
OC   Desulfurococcaceae; Aeropyrum.
OX   NCBI_TaxID=272557;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS AEPER1_1.PE1015.
CC       Aeropyrum pernix K1, complete genome.
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:APEH_AERPE
CC   -!- FUNCTION: This enzyme catalyzes the hydrolysis of the N-terminal
CC       peptide bond of an N-acetylated peptide to generate an N-
CC       acetylated amino acid and a peptide with a free N-terminus.
CC   -!- CATALYTIC ACTIVITY: Cleavage of an N-acetyl or N-formyl amino acid
CC       from the N-terminus of a polypeptide.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the peptidase S9C family.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA80546.2; Type=Erroneous initiation;
CC   -!- GENE_FAMILY: HOG000115412 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q9YBQ2; -.
DR   EMBL; BA000002; BAA80546.2; ALT_INIT; Genomic_DNA.
DR   PIR; D72636; D72636.
DR   RefSeq; NP_148014.2; NC_000854.2.
DR   PDB; 1VE6; X-ray; 2.10 A; A/B=1-582.
DR   PDB; 1VE7; X-ray; 2.70 A; A/B=1-582.
DR   PDB; 2HU5; X-ray; 2.00 A; A/B=1-582.
DR   PDB; 2HU7; X-ray; 2.01 A; A/B=1-582.
DR   PDB; 2HU8; X-ray; 2.40 A; A/B=1-582.
DR   PDB; 2QR5; X-ray; 2.20 A; A/B=1-582.
DR   PDB; 2QZP; X-ray; 2.70 A; A/B=21-582.
DR   PDB; 3O4G; X-ray; 2.50 A; A/B/C/D=1-582.
DR   PDB; 3O4H; X-ray; 1.82 A; A/B/C/D=1-582.
DR   PDB; 3O4I; X-ray; 2.70 A; A/B=1-582.
DR   PDB; 3O4J; X-ray; 2.50 A; A/B/C/D=1-582.
DR   PDBsum; 1VE6; -.
DR   PDBsum; 1VE7; -.
DR   PDBsum; 2HU5; -.
DR   PDBsum; 2HU7; -.
DR   PDBsum; 2HU8; -.
DR   PDBsum; 2QR5; -.
DR   PDBsum; 2QZP; -.
DR   PDBsum; 3O4G; -.
DR   PDBsum; 3O4H; -.
DR   PDBsum; 3O4I; -.
DR   PDBsum; 3O4J; -.
DR   ProteinModelPortal; Q9YBQ2; -.
DR   SMR; Q9YBQ2; 8-582.
DR   DisProt; DP00248; -.
DR   MEROPS; S09.070; -.
DR   GeneID; 1446086; -.
DR   GenomeReviews; BA000002_GR; APE_1547.1.
DR   KEGG; ape:APE_1547.1; -.
DR   NMPDR; fig|272557.1.peg.1122; -.
DR   OMA; GESYWIY; -.
DR   ProtClustDB; CLSK270850; -.
DR   BioCyc; APER272557:APE1547-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR001375; Peptidase_S9.
DR   InterPro; IPR004106; Peptidase_S9A_B_C_N.
DR   Gene3D; G3DSA:2.120.10.30; 6-blade_b-propeller_TolB-like; 1.
DR   Pfam; PF00326; Peptidase_S9; 1.
DR   SUPFAM; SSF50993; Peptidase_S9A_N; 1.
DR   PROSITE; PS00708; PRO_ENDOPEP_SER; FALSE_NEG.
DR   HOGENOMDNA; AEPER1_1.PE1015; -.
KW   acylamino-acid-releasing enzyme;
KW   3D-structure; Complete proteome; Cytoplasm; Hydrolase.
SQ   SEQUENCE   578 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MPVEFSRIVR DVERLIAVEK YSLQGVVDGD KLLVVGFSEG SVNAYLYDGG ETVKLNREPI
     NSVLDPHYGV GRVILVRDVS KGAEQHALFK VNTSRPGEEQ RLEAVKPMRI LSGVDTGEAV
     VFTGATEDRV ALYALDGGGL RELARLPGFG FVSDIRGDLI AGLGFFGGGR VSLFTSNLSS
     GGLRVFDSGE GSFSSASISP GMKVTAGLET AREARLVTVD PRDGSVEDLE LPSKDFSSYR
     PTAITWLGYL PDGRLAVVAR REGRSAVFID GERVEAPQGN HGRVVLWRGK LVTSHTSLST
     PPRIVSLPSG EPLLEGGLPE DLRRSIAGSR LVWVESFDGS RVPTYVLESG RAPTPGPTVV
     LVHGGPFAED SDSWDTFAAS LAAAGFHVVM PNYRGSTGYG EEWRLKIIGD PCGGELEDVS
     AAARWARESG LASELYIMGY SYGGYMTLCA LTMKPGLFKA GVAGASVVDW EEMYELSDAA
     FRNFIEQLTG GSREIMRSRS PINHVDRIKE PLALIHPQND SRTPLKPLLR LMGELLARGK
     TFEAHIIPDA GHAINTMEDA VKILLPAVFF LATQRERR
//

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