(data stored in ACNUC7421 zone)

HOGENOM: AERHH_1_PE2096

ID   AERHH_1_PE2096                       STANDARD;      PRT;   715 AA.
AC   AERHH_1_PE2096; A0KK77;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=Fatty oxidation complex, alpha subunit FadJ; EC=1.1.1.35;
DE   EC=4.2.1.17; EC=5.1.2 3; (AERHH_1.PE2096).
GN   Name=fadJ; OrderedLocusNames=AHA_2154;
OS   AEROMONAS HYDROPHILA SUBSP. HYDROPHILA ATCC 7966.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=380703;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS AERHH_1.PE2096.
CC       Aeromonas hydrophila subsp. hydrophila ATCC 7966, complete genome.
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:A0KK77_AERHH
CC   -!- CATALYTIC ACTIVITY: (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-
CC       CoA + H(2)O.
CC   -!- CATALYTIC ACTIVITY: (S)-3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA
CC       + NADH.
CC   -!- CATALYTIC ACTIVITY: (S)-3-hydroxybutanoyl-CoA = (R)-3-
CC       hydroxybutanoyl-CoA.
CC   -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC   -!- SUBUNIT: Heterotetramer of two alpha chains (fadJ) and two beta
CC       chains (fadI) (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000261346 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A0KK77; -.
DR   EMBL; CP000462; ABK39196.1; -; Genomic_DNA.
DR   RefSeq; YP_856678.1; NC_008570.1.
DR   ProteinModelPortal; A0KK77; -.
DR   STRING; A0KK77; -.
DR   GeneID; 4487970; -.
DR   GenomeReviews; CP000462_GR; AHA_2154.
DR   KEGG; aha:AHA_2154; -.
DR   TIGR; AHA_2154; -.
DR   eggNOG; COG1250; -.
DR   OMA; YLAHIEN; -.
DR   PhylomeDB; A0KK77; -.
DR   ProtClustDB; PRK11154; -.
DR   GO; GO:0016507; C:fatty acid beta-oxidation multienzyme complex; IEA:InterPro.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.
DR   GO; GO:0008692; F:3-hydroxybutyryl-CoA epimerase activity; IEA:EC.
DR   GO; GO:0004300; F:enoyl-CoA hydratase activity; IEA:EC.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IEA:InterPro.
DR   InterPro; IPR006180; 3-OHacyl-CoA_DH_CS.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH_C-like.
DR   InterPro; IPR001753; Crotonase_core.
DR   InterPro; IPR013328; DH_multihelical.
DR   InterPro; IPR012802; FadJ.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   Gene3D; G3DSA:1.10.1040.10; Opine_DH; 2.
DR   Pfam; PF00725; 3HCDH; 2.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   Pfam; PF00378; ECH; 1.
DR   SUPFAM; SSF48179; 6DGDH_C_like; 2.
DR   TIGRFAMs; TIGR02440; FadJ; 1.
DR   PROSITE; PS00067; 3HCDH; 1.
DR   HOGENOMDNA; AERHH_1.PE2096; -.
KW   Complete proteome; Cytoplasm; Fatty acid metabolism; Isomerase;
KW   Lipid degradation; Lipid metabolism; Lyase; Multifunctional enzyme;
KW   NAD; Oxidoreductase.
SQ   SEQUENCE   715 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSEKTFSLAV RQDGIGILTM DVPGESMNTL KAAFVEEIRA VLAEVKANKE LIGLVVVSGK
     KDSFIAGADI SMLAACTSAK DAETLSREGQ VIFAEIESLP IPVIAAIHGP CLGGGLELAL
     ACHGRVVTDH GKTVLGLPEV QLGLLPGSGG TQRLPRLIGV AKALDLMLTG KQVRAKQAKK
     LGLVDDVVPP SILLDAAIKL AKKGKPRHEL KRDLQGKLLE TNKLGRKVLF DQARKGVKAK
     TRGNYPAPDL ILEVVRIGVE EGMQAGLAAE SRHFGELVMT AESAALRSIF FATTEMKKEV
     TYQGAEPRKV GHAAVLGGGL MGGGIAFVTA TKAGVPVRIK DVASSGIGNA MRYSYDILAK
     KLKRRQLLRS ELEKQMSLLT GTLDYSGFHR VDMVVEAVFE DLSLKHQMVK DVERECGEHT
     VFASNTSSLP IHQIASVAAH PERVVGLHYF SPVDKMPLAE IIPHAGTSAE TVATTLAFAR
     AQGKTPIVVK DEAGFYVNRI LAPYMNEAAR LVLEGEPVEV LDGALLDFGF PVGPITLLDE
     VGIDVGAKIS PILEKELGGE QFQAPAAFNK LLQNDRKGRK NGKGFYLYGK AAPRSKLTGK
     EGKKMVDESV YGVLGISPQA KLAKTELAER CVLMMLNEAA MALDSGVVAS ARDGDIGAIF
     GIGFPPFLGG PFRYMDSLGI EHLVGRLEHY QKRYGDRFAP CDRLKAMAAE QQRFY
//

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