(data stored in SCRATCH3701 zone)

HOGENOM6: AGGAN_1_PE336

ID   AGGAN_1_PE336                        STANDARD;      PRT;   885 AA.
AC   AGGAN_1_PE336; C6ALH9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; (AGGAN_1.PE336).
GN   OrderedLocusNames=NT05HA_0358;
OS   AGGREGATIBACTER APHROPHILUS NJ8700.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Aggregatibacter.
OX   NCBI_TaxID=634176;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS AGGAN_1.PE336.
CC       Aggregatibacter aphrophilus NJ8700, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:C6ALH9_AGGAN
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C6ALH9; -.
DR   EMBL; CP001607; ACS96785.1; -; Genomic_DNA.
DR   RefSeq; YP_003006872.1; NC_012913.1.
DR   STRING; C6ALH9; -.
DR   GeneID; 8123063; -.
DR   GenomeReviews; CP001607_GR; NT05HA_0358.
DR   KEGG; aap:NT05HA_0358; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; AGGAN_1.PE336; -.
DR   PRODOM; AGGAN_1_PE336.
DR   SWISS-2DPAGE; AGGAN_1_PE336.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   885 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDLVQDITP VSIEEELKSS YLDYAMSVIV GRALPDVRDG LKPVHRRVLF AMHEGGNAYN
     KPYRKSARIV GDVIGKYHPH GDSAVYDTLV RMAQPFSLRY MLVDGQGNFG SVDGDAPAAM
     RYTEARMTKI AHELLADLDK ETVNFVPNYD GSEQIPEVLP TKVPALLVNG SSGIAVGMAT
     NIPPHNLGEV LDGCLAYIEN NDITIDELMS HIPGPDFPTA ALINGRKGIE EAYKTGRGKI
     YVRAKAEIET DEKGRETIIV NEIPYQVNKA KLIEKIAEFV KEKKIEGISG LRDESDKDGM
     RIVIEIKRDA VGEVVLNNLY ALTQMQVTFG INIVALDHGQ PKLLNLKQLI EAFVLHRREV
     VTRRTIFELR KARERTHILE GLAIALANVD PIIELIRQAP NPETAKRELI ARPWQLGHVA
     DMLAAAGVDA ARPEDLDEQY GIRDGLYYLT EVQAQAILDL RLQKLTNLGH DEILDEYKKL
     LEAIGELLHI LRSPERLMEV IREELEQIRE QFNDPRRTEI TAASGDINLE DLIAQEDVVV
     TLSHEGYVKY QPITDYEAQR RGGKGKSATK MKEEDFIEKL LVANTHDTIL CFSSRGRLYW
     LKVYQLPQAS RGSRGRPIVN ILPLGENERI TAILPVTAYE EDKFVIMATA GGVVKKIALT
     EFSRPRSSGI IALNLRDEDE LIGVDITDGS NEIMLFSSQG RVVRFSETAV RAMGRLATGV
     RGIKLALTND LSDDESAVEI EDVSDDNAEE TLDLNIDKVV SLVVPKNNGE ILTATQNGYG
     KRTKLEEYPT KSRNTKGVIS IKVSERNGKV VAATQVIDTD QIMLITDAGT LVRTRVSEVS
     IIGRNTQGVR LIRTSEDEHV VSLERICDVD DEEGEQESAV ENTEE
//

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