(data stored in SCRATCH3701 zone)

HOGENOM6: AKKM8_1_PE1264

ID   AKKM8_1_PE1264                       STANDARD;      PRT;   873 AA.
AC   AKKM8_1_PE1264; B2URM6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (AKKM8_1.PE1264).
GN   OrderedLocusNames=Amuc_1286;
OS   AKKERMANSIA MUCINIPHILA ATCC BAA-835.
OC   Bacteria; Verrucomicrobia; Verrucomicrobiae; Verrucomicrobiales;
OC   Verrucomicrobiaceae; Akkermansia.
OX   NCBI_TaxID=349741;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS AKKM8_1.PE1264.
CC       Akkermansia muciniphila ATCC BAA-835, complete genome.
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:B2URM6_AKKM8
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B2URM6; -.
DR   EMBL; CP001071; ACD05111.1; -; Genomic_DNA.
DR   RefSeq; YP_001877892.1; NC_010655.1.
DR   ProteinModelPortal; B2URM6; -.
DR   STRING; B2URM6; -.
DR   GeneID; 6275539; -.
DR   GenomeReviews; CP001071_GR; Amuc_1286.
DR   KEGG; amu:Amuc_1286; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; AKKM8_1.PE1264; -.
DR   PRODOM; AKKM8_1_PE1264.
DR   SWISS-2DPAGE; AKKM8_1_PE1264.
KW   DNA gyrase, A subunit;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   873 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MENNRIKPVD VASELSTSFL DYSMSVIISR ALPDVRDGLK PSQRRILYAM KELNLSPGGK
     TRKCSKIVGD TMGNYHPHGD AAIYGTLVNM AQDWSMRDIL VIGQGNFGTP DGDPPAAARY
     TEAKLSGMGV ALMADLDKDT VDFVPTYDNE HTEPTVFPSA FPNLLVNGGT GIAVGMATNM
     PPHNLGEVVD GICAVIDNPH MTVEELRQYI KGPDFPTGGD VLGFSGIDNY FRTGRGSVRI
     RGKIDMEVTD SGKDLLIIRE VPYGVNRAAL QERIAELYKD KILTDISGIR DLSDEKTCIE
     IELKRDARPQ VVMNQLYKLT SMETSFAVNM LAIHDNRPKT LAMMDAINFY IEHRREVVVR
     RTRYLLGDAE KDAERLEAFL LALHHMDDFI SIIRDSKNRD EARERLQNYT FSTQTAESLG
     ILIRSQASIQ GDRYVFTERQ VNSILDLRLY QLTALENDKI SGEYAELLVR IKDYLDILAN
     ESRVLGIVKD ELKAIKDKYA TPRVTRIIPF SGDMAIEDLI PNDTMIVTIT HSGYIKRTNS
     AEYRVQARGG KGVKAATTRG AKKDAEADFI EHLFAAQNHD YLMFFTNTGR VYVDRVYEID
     EAARSAQGRN IKNLLDLQPE EAIAAILRLE RRVDEKGNDI TFAEGSGNVV FATKDGTVKK
     TSLNDFANYR KAGIIAINLE EGNSLVNAEL TSGADEIVLV THDGMSIRFP EEDLRTQGRN
     TIGVRGIRPR AGDYVVALAI VDPQKTLLVA SENGLGKRTS FDEYRTQGRG GTGIKTMNCT
     DKTGKVVSAT VVSDEDELML MTTAGQSVRI KVATVRETGR ATQGVKLMTL NEGESIQDIS
     IVIPDDEDEE APAETEDAGA GEVSGEMEAP AEE
//

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