(data stored in SCRATCH zone)

HOGENOM: ALCBS_1_PE1009

ID   ALCBS_1_PE1009                       STANDARD;      PRT;   204 AA.
AC   ALCBS_1_PE1009; Q0VQU1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=LexA repressor; EC=3.4.21 88; (ALCBS_1.PE1009).
GN   Name=lexA; OrderedLocusNames=ABO_1009;
OS   ALCANIVORAX BORKUMENSIS SK2.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales;
OC   Alcanivoracaceae; Alcanivorax.
OX   NCBI_TaxID=393595;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ALCBS_1.PE1009.
CC       Alcanivorax borkumensis SK2, complete genome.
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:LEXA_ALCBS
CC   -!- FUNCTION: Represses a number of genes involved in the response to
CC       DNA damage (SOS response), including recA and lexA. In the
CC       presence of single-stranded DNA, recA interacts with lexA causing
CC       an autocatalytic cleavage which disrupts the DNA-binding part of
CC       lexA, leading to derepression of the SOS regulon and eventually
CC       DNA repair (By similarity).
CC   -!- CATALYTIC ACTIVITY: Hydrolysis of Ala-|-Gly bond in repressor
CC       lexA.
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the peptidase S24 family.
CC   -!- GENE_FAMILY: HOG000232167 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q0VQU1; -.
DR   EMBL; AM286690; CAL16457.1; -; Genomic_DNA.
DR   RefSeq; YP_692729.1; NC_008260.1.
DR   ProteinModelPortal; Q0VQU1; -.
DR   STRING; Q0VQU1; -.
DR   MEROPS; S24.001; -.
DR   GeneID; 4211543; -.
DR   GenomeReviews; AM286690_GR; ABO_1009.
DR   KEGG; abo:ABO_1009; -.
DR   NMPDR; fig|393595.12.peg.1016; -.
DR   eggNOG; COG1974; -.
DR   OMA; THRHSPS; -.
DR   PhylomeDB; Q0VQU1; -.
DR   BioCyc; ABOR393595:ABO_1009-MON; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
DR   HAMAP; MF_00015; LexA; 1; -.
DR   InterPro; IPR006199; LexA_DNA-bd_dom.
DR   InterPro; IPR006200; Pept_S24_LexA.
DR   InterPro; IPR006197; Peptidase_S24_LexA.
DR   InterPro; IPR019759; Peptidase_S24_S26.
DR   InterPro; IPR015927; Peptidase_S24_S26A/B/C.
DR   InterPro; IPR011056; Peptidase_S24_S26A/B/C_b-rbn.
DR   InterPro; IPR011991; WHTH_trsnscrt_rep_DNA-bd.
DR   Gene3D; G3DSA:2.10.109.10; Pept_S24_S26_C; 1.
DR   Gene3D; G3DSA:1.10.10.10; Wing_hlx_DNA_bd; 1.
DR   Pfam; PF01726; LexA_DNA_bind; 1.
DR   Pfam; PF00717; Peptidase_S24; 1.
DR   PRINTS; PR00726; LEXASERPTASE.
DR   SUPFAM; SSF51306; Pept_S24_S26_C; 1.
DR   TIGRFAMs; TIGR00498; LexA; 1.
DR   HOGENOMDNA; ALCBS_1.PE1009; -.
KW   Autocatalytic cleavage; Complete proteome; DNA damage; DNA repair;
KW   DNA replication; DNA-binding; Hydrolase; Repressor; SOS response;
KW   Transcription; Transcription regulation.
SQ   SEQUENCE   204 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSSKLTDRQQ QVLDCIRECL KDNGMAPTRA EIADIMGFQS KNAASDHLRA LERKGYIKLH
     SDRSRGIQLL DHAYWGEEEL PVVGKVAAGI PIEAIENVER TVPVPQGLFK QRPTYLLKVQ
     GDSMVDAGIF DGDLIAVRKS NVARSGEIVV ARIDEEVTVK TLKLNKSSAT LLPANEAYEP
     IKVPADQLII EGIFVGLIRD PNSF
//

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