(data stored in SCRATCH zone)

HOGENOM: ALCBS_1_PE1012

ID   ALCBS_1_PE1012                       STANDARD;      PRT;   909 AA.
AC   ALCBS_1_PE1012; Q0VQT8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA topoisomerase; EC=5.99.1 2; (ALCBS_1.PE1012).
GN   Name=topA; OrderedLocusNames=ABO_1012;
OS   ALCANIVORAX BORKUMENSIS SK2.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales;
OC   Alcanivoracaceae; Alcanivorax.
OX   NCBI_TaxID=393595;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ALCBS_1.PE1012.
CC       Alcanivorax borkumensis SK2, complete genome.
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:Q0VQT8_ALCBS
CC   -!- FUNCTION: The reaction catalyzed by topoisomerases leads to the
CC       conversion of one topological isomer of DNA to another (By
CC       similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-independent breakage of single-stranded
CC       DNA, followed by passage and rejoining.
CC   -!- SIMILARITY: Belongs to the prokaryotic type I/III topoisomerase
CC       family.
CC   -!- SIMILARITY: Contains 1 Toprim domain.
CC   -!- GENE_FAMILY: HOG000004018 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q0VQT8; -.
DR   EMBL; AM286690; CAL16460.1; -; Genomic_DNA.
DR   RefSeq; YP_692732.1; NC_008260.1.
DR   ProteinModelPortal; Q0VQT8; -.
DR   SMR; Q0VQT8; 2-584, 764-881.
DR   STRING; Q0VQT8; -.
DR   GeneID; 4211920; -.
DR   GenomeReviews; AM286690_GR; ABO_1012.
DR   KEGG; abo:ABO_1012; -.
DR   NMPDR; fig|393595.12.peg.1019; -.
DR   eggNOG; COG0550; -.
DR   OMA; EEYWSID; -.
DR   PhylomeDB; Q0VQT8; -.
DR   ProtClustDB; PRK07561; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR000380; Topo_IA.
DR   InterPro; IPR003601; Topo_IA_2.
DR   InterPro; IPR023406; Topo_IA_AS.
DR   InterPro; IPR013497; Topo_IA_cen.
DR   InterPro; IPR013824; Topo_IA_cen_sub1.
DR   InterPro; IPR013825; Topo_IA_cen_sub2.
DR   InterPro; IPR023405; Topo_IA_core_domain.
DR   InterPro; IPR003602; Topo_IA_DNA-bd.
DR   InterPro; IPR013498; Topo_IA_Znf.
DR   InterPro; IPR005733; TopoI_bac-type.
DR   InterPro; IPR013263; TopoI_Znr_bac.
DR   InterPro; IPR006171; Toprim_domain.
DR   Gene3D; G3DSA:1.10.460.10; Topo_IA_cen_sub1; 2.
DR   Gene3D; G3DSA:2.70.20.10; Topo_IA_cen_sub2; 2.
DR   PANTHER; PTHR11390; Topo_IA; 1.
DR   Pfam; PF08272; Topo_Zn_Ribbon; 2.
DR   Pfam; PF01131; Topoisom_bac; 1.
DR   Pfam; PF01751; Toprim; 1.
DR   Pfam; PF01396; zf-C4_Topoisom; 2.
DR   PRINTS; PR00417; PRTPISMRASEI.
DR   SMART; SM00437; TOP1Ac; 1.
DR   SMART; SM00436; TOP1Bc; 1.
DR   SMART; SM00493; TOPRIM; 1.
DR   SUPFAM; SSF56712; Topo_IA_core; 1.
DR   TIGRFAMs; TIGR01051; TopA_bact; 1.
DR   PROSITE; PS00396; TOPOISOMERASE_I_PROK; 1.
DR   HOGENOMDNA; ALCBS_1.PE1012; -.
KW   ATP-binding; Complete proteome; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   909 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MGKSLVIVES PAKAKTINRY LGDDFIVKSS VGHVRDLPVS GGSKKSTPQE RAKEAAYTRS
     LPKEERDAYK KKKAKKQLIN RMGIDPENGW AAHYEVLPGK DKVVDELKRL AAKADRIYLA
     TDLDREGEAI AWHLREVIGG DEERFDRVVF NEITKKAIQA AFEEPGKLDL HRVEAQQARR
     FLDRVVGFMI SPLLWEKIAR GLSAGRVQSV AVELVVERER EIRAFIPEEF WELYSDTHSG
     DGEALRLQVA KHNGLAFRPN NGDDAAAHKQ ALENAGRLTI SQREQRPTRS KPSAPFITST
     LQQAASTRLG FGVKKTMMMA QRLYEAGHIT YMRTDSTNLS SDAVAACREW IGEKLGDKYL
     PDEPLSYSSK EGAQEAHEAI RPSDVRRTSD SLKDMERDAQ RLYELIRRQF IACQMPPAEY
     LSSTLTAIGN GYELKAKGRI MKFDGWTRIQ PPASRKGQED TLLPDVKEGD VLAIDNVDAN
     QHFTKPPARF TEASLVKELE KRGIGRPSTY AAIISTIQDR GYVRQDNRRF YAEKMGDIVT
     DRLVESFPNL MDYGFTASME ETLDEVAEGR RNWQDVLNEF YKDFVSKLDA AQGEGTGKQA
     VGGMRANLPT DTDIECPSCG RPMQIRTGST GVFLGCSGYA LPPKERCTAT LNLLPGEEAE
     AVKTDDDEEA ETNELRSKKR CQKCGTAMEN YLIDEKRKLH ICGNNPDCDG YVIEKGEFRI
     KGYDGPVLEC EKCGNDMQLR TGRFGKFFKC TNDECGNTRK LLKSGEPAPP RADPIPMPHL
     QCQKVDDHYL LRDGASGLFL AASKFPKNRE TRPPLIEEIQ SVAEQLDPKH AYLAQAPATD
     PDGNKGVLRY SRKAKEQYVM SEIDGKATGW MAFYRDGKWV EEQAKKKAPA KKKAAAKKKA
     TKKKAAAKK
//

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